Results 71 to 80 of about 10,287 (223)

Anshen Jieyu Decoction: A Promising Remedy for Depression via AKT/mTOR Pathway Modulation in CUMS Rats

Brain and Behavior, Volume 16, Issue 4, April 2026.
An Shen Jie Yu Tang ameliorates depression‐like behaviors in chronically stressed rats. Its mechanism involves suppressing HPA axis hyperactivity and activating the hippocampal AKT/mTOR signaling pathway, leading to neuroprotective effects. ABSTRACT Objective To investigate the effects of An Shen Jie Yu Tang (ASJYD) on hippocampal morphology, AKT/mTOR ...
Zhen Li, Zijun Ji, Zehao Zhang, Xuzhang Wang, Hongyue Yu, Dongrun Yang, Huijin Zhang, Yongsheng Liu, Zhuxin Sui   +8 more
wiley   +1 more source

Case Report: Scar‐Like Alterations of the Gastric Mucosa Observed Under Endoscopy in Collagenous Gastritis

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Collagenous gastritis (CG) is an uncommon disorder of the digestive system, characterized by marked thickening of the subepithelial collagen band and infiltration of inflammatory cells within the lamina propria. The etiology and pathogenesis of CG remain not fully understood, and its diagnosis is contingent upon histopathological evaluation ...
Qian Luo, Yujie Li, Jiemin Liu, Xiaoyuan Lin, Sainan Zhou   +4 more
wiley   +1 more source

Genome resequencing reveals the genetic basis of population evolution, local adaptation, and rewiring of the rhizome metabolome in Atractylodes lancea

Horticulture Research
The formation of high-quality Chinese medicinal materials is a micro-evolutionary process of multiple genes involving quantitative inheritance under environmental stress.
Cheng-cai Zhang, Sheng Wang, Jiahui Sun, Xiangkong Li, Hongyang Wang, Xiuzhi Guo, Yuefeng Wang, Daiquan Jiang, Chaogeng Lyu, Chuanzhi Kang, Yan Zhang, Zengxu Xiang, Qingjun Yuan, Binbin Yan, Ming Qin, Luqi Huang, Lanping Guo   +16 more
semanticscholar   +1 more source

Atractylodes Macrocephala Polysaccharides Ameliorate Diabetic Hepatorenal Injury and Remodel Gut Microbiota in Mice

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Atractylodes macrocephala polysaccharides alleviate diabetic liver and kidney injury in HFD/STZ‐induced mice by improving gut microbiota composition, restoring intestinal barrier function, and partially correcting disturbed unsaturated fatty acid metabolism.
Jiali Wu, Xuenan Liu, Yangpeng Li, Jing Liu, Biao Jia, Hongye Peng, Qin Yuan, Wen Liu, Shengpeng Wang, Duosheng Luo, Xianglu Rong, Wenliang Lv, Jiao Guo   +12 more
wiley   +1 more source

A systematic review on the application, phytochemistry and pharmacological activities of the genus Atractylodes

Chinese Medicine
The genus Atractylodes (Asteraceae) is widely distributed and utilized in East and Southeast Asia, particularly in China, Japan, Korea and Thailand. In traditional Chinese medicine, representative species such as A. lancea and A.
Siwei Luo, Jiameng Jiang, Dongmei Zhang, Ligen Lin, Qingwen Zhang   +4 more
doaj   +1 more source

Phytochemistry and Pharmacology of Sesquiterpenoids from Atractylodes DC. Genus Rhizomes

Molecules
The rhizomes of the genus Atractylodes DC. consist of various bioactive components, including sesquiterpenes, which have attracted a great deal of research interest in recent years.
Zhengyi Qu, Hongqun Liu, Zhenghai Zhang, Peihe Zheng, Shuting Zhao, Wei Hou   +5 more
doaj   +1 more source

The Bufei Nashen Pill Alleviates COPD by Targeting Endoplasmic Reticulum Stress Through the PERK/eIF2α Signaling Pathway

Immunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
ABSTRACT Background Evidence supporting the therapeutic efficacy of Bufei Nashen pill (BFNSP) for chronic obstructive pulmonary disease (COPD) is currently limited. We evaluated BFNSP's effects on COPD progression and elucidated its potential mechanisms through LC/MS analysis of its active components.
Tengfei He, Anni Zhang, Changxi Zhang
wiley   +1 more source

Protective effects of Atractylodes macrocephala polysaccharides on acetaminophen-induced liver injury

Frontiers in Pharmacology
Background Drug-induced liver injury (DILI) is a major clinical concern due to its unpredictable nature and lack of effective therapeutic options. Methods This study investigated the hepatoprotective effects of Atractylodes macrocephala polysaccharides ...
Jiali Wu, Biao Jia, Shuai Gong, Yangpeng Li, Jiaqi Wang, Yuqiao Huang, Jiao Guo   +6 more
semanticscholar   +1 more source

Research progress on extraction, separation, structure, and biological activities of polysaccharides from the genus Atractylodes: A review.

International Journal of Biological Macromolecules
Plants of the genus Atractylodes are perennial herbaceous plants in the family Asteraceae, whose rhizome is often used in the production of medicines and health products. There are 6 main species in this genus, namely A. macrocephala, A.
Fei Lin, Yang Xu, Bin Liu, Hua Li, Lixia Chen   +4 more
semanticscholar   +1 more source

The effects of Atractylodes macrocephala extract BZEP self-microemulsion based on gut-liver axis HDL/LPS signaling pathway to ameliorate metabolic dysfunction-associated fatty liver disease in rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
OBJECTIVES To elucidate the therapeutic effects and mechanisms of Atractylodes macrocephala extract crystallize (BZEP) and BZEP self-microemulsion (BZEPWR) on metabolic dysfunction-associated fatty liver disease (MAFLD) induced by "high sugar, high fat ...
Bo Li, Xiaofeng Jiang, Ying-Jie Dong, Yi-Piao Zhang, Xinglishang He, Cheng-liang Zhou, Yan-Yan Ding, Ning Wang, Yi-bin Wang, Wang Cheng, Ning Jiang, Jie Su, Guiyuan Lv, Suhong Chen   +13 more
semanticscholar   +1 more source