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Receptors of Atrial Natriuretic Factor
Annual Review of Physiology, 1992Atrial natriuretic factor (ANF) is a polypeptide hormone that is secreted mainly by the heart atria in response to increases in atrial pressure or atrial stretch. ANF has multiple actions in the kidney that lead to increases in glomerular filtration rate and excretion of fluid and electrolytes, modulation of renal vascular resistance, decreases in ...
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1986
Various groups have recently reported on the existence of atrial natriuretic peptides (ANP) in secretorylike granules present in the myocytes of mammalian atria. These newly isolated peptides include the atrial natriuretic factors (ANF) (Grammer et al., 1983; Thibault et al., 1983a,b, 1984; Lazure et al., 1984; Napier et al., 1984a; Seidah et al., 1984)
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Various groups have recently reported on the existence of atrial natriuretic peptides (ANP) in secretorylike granules present in the myocytes of mammalian atria. These newly isolated peptides include the atrial natriuretic factors (ANF) (Grammer et al., 1983; Thibault et al., 1983a,b, 1984; Lazure et al., 1984; Napier et al., 1984a; Seidah et al., 1984)
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Release of atrial natriuretic factor
Scandinavian Journal of Clinical and Laboratory Investigation, 1993The cardiac atria synthesize and store a hormone termed atrial natriuretic factor (ANF). ANF is released into the systemic circulation, and the circulating 28 amino acid peptide can be measured by radioimmunoassay. The hormone participates in body fluid homeostasis through its effect on renal sodium excretion and by inducing a shift of circulating ...
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Annales francaises d'anesthesie et de reanimation, 1990
Although ANF research started 30 years ago, the atrial natriuretic factor (ANF) was only discovered recently (1981). The presence of such a factor has been suspected for many years because of histological and physiological arguments. In 1956, Kish found "dense granules" in the atrial walls of guinea pigs.
A, Mebazaa, D, Payen
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Although ANF research started 30 years ago, the atrial natriuretic factor (ANF) was only discovered recently (1981). The presence of such a factor has been suspected for many years because of histological and physiological arguments. In 1956, Kish found "dense granules" in the atrial walls of guinea pigs.
A, Mebazaa, D, Payen
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Atrial Natriuretic Factor In Edematous Disorders
Annual Review of Medicine, 1990This article provides a brief overview of atrial natriuretic factor (ANF). Considered by many investigators to be the putative "third factor" governing sodium excretion, ANF is a peptide actively secreted by the heart, with multiple target organ effectors. As such, ANF represents the first clearly documented cardiac hormone.
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Renal Effects Of Atrial Natriuretic Factor
Annual Review of Physiology, 1990A prominent effect of atrial natriuretic factor (ANF), indeed that for which it is named, is the ability to effect a solute and water diuresis. The renal mechanisms responsible for this natriuresis and diuresis have been subjects of intensive inquiry since the hormone's discovery in 1981.
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Atrial natriuretic factor—a circulating hormone stimulated by volume loading
Nature, 1985R. Lang +5 more
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Atrial natriuretic factor: a hormone produced by the heart.
Science, 1985A. J. Bold
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Physiological role of silent receptors of atrial natriuretic factor.
Science, 1987T. Maack +6 more
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The heart and the atrial natriuretic factor.
Endocrine reviews, 1985M. Cantin, J. Genest
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