Results 31 to 40 of about 142,764 (336)

Regulated Inositol‐Requiring Protein 1‐Dependent Decay as a Mechanism of Corin RNA and Protein Deficiency in Advanced Human Systolic Heart Failure [PDF]

, 2014
BACKGROUND: The compensatory actions of the endogenous natriuretic peptide system require adequate processing of natriuretic peptide pro‐hormones into biologically active, carboxyl‐terminal fragments.
Barton, P, Dries, DL, Felkin, LE, Lee, R, Rame, JE, Xu, B   +5 more
core   +1 more source

Plasma natriuretic peptides in children and adolescents with obstructive sleep apnoea and their changes following intervention

Frontiers in Pediatrics, 2014
Objective: This study aimed to evaluate circulating natriuretic peptides (NP) concentration in obese and non-obese children and adolescents with and without OSA, and their levels following OSA treatment.Methods: Subjects with habitual snoring and ...
Albert Martin Li, Chun T eAu, Jodie eZhu, Kate eChan, Michael eChan, Dennis eLee, Yun K eWing   +6 more
doaj   +1 more source

Signs of left atrial disease and 10-year risk of atrial fibrillation.

PLoS ONE, 2022
BackgroundThe contribution of left atrial disease and excessive supraventricular ectopic activity (ESVEA) to the risk for incident atrial fibrillation (AF) is incompletely understood.ObjectiveTo analyse the ten-year risk to develop AF in patients with ...
Tobias Uhe, Tina Stegmann, Romy Langhammer, Nikolaos Dagres, Ulrich Laufs, Rolf Wachter   +5 more
doaj   +1 more source

Different behaviour of the N-terminal and C-terminal fragment of proatrial natriuretic factor in plasma of healthy subjects as well as of patients with cirrhosis [PDF]

, 1990
N-terminal (atrial natriuretic factor (ANF) 1-98) and C-terminal (ANF 99-126) fragments of proatrial natriuretic factor (NTA and CTA, respectively) were determined in plasma of healthy subjects adopting different postures and in patients with cirrhosis ...
Arendt, Rainer M., Cantin, M., Gerbes, Alexander L., Paumgartner, Gustav, Thibault, G., Vollmar, Angelika M.   +5 more
core   +1 more source

Biomarkers for predicting atrial fibrillation: An explorative sub-analysis of the randomised SCREEN-AF trial

European Journal of General Practice
Background Atrial fibrillation (AF) is a common treatable risk factor for stroke. Screening for paroxysmal AF in general practice is difficult, but biomarkers might help improve screening strategies.Objectives We investigated six blood biomarkers for ...
Katharina Schmalstieg-Bahr, David J. Gladstone, Eva Hummers, Johanna Suerbaum, Jeff S. Healey, Antonia Zapf, Denise Köster, Stefanie M. Werhahn, Rolf Wachter   +8 more
doaj   +1 more source

Programmed Exercise Attenuates Familial Hypertrophic Cardiomyopathy in Transgenic E22K Mice via Inhibition of PKC-α/NFAT Pathway

Frontiers in Cardiovascular Medicine, 2022
Familial hypertrophic cardiomyopathy (FHCM), an autosomal dominant disease, is caused by mutations in genes encoding cardiac sarcomeric proteins. E22K, a mutation in the myosin regulatory light chain sarcomere gene, is associated with the development of ...
Haiying Wang, Yuedong Lin, Ran Zhang, Yafen Chen, Wei Ji, Shenwei Li, Li Wang, Rubin Tan, Jinxiang Yuan   +8 more
doaj   +1 more source

Atrial Natriuretic Peptide, a Regulator of Nuclear Factor-κB Activation in Vivo [PDF]

, 2007
Natriuretic peptides (NPs) comprise a family of vasoactive hormones that play important roles in the regulation of cardiovascular and renal homeostasis.
Keller, Melanie, Kiemer, Alexandra K., Koch, Elke, Ladetzki-Baehs, Kathrin, Vollmar, Angelika M., Wendel, Albrecht, Zahler, Stefan   +6 more
core   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

Plasma Biomarkers Associated With Heart Failure Hospitalization Among Patients With Atrial Fibrillation and Subtypes of Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Atrial fibrillation is associated with heart failure (HF) through a complex cause‐and‐effect relationship. We performed multiplex screening of plasma proteins in patients with atrial fibrillation to identify biomarkers and pathways associated ...
Tymon Pol, Johan Lindbäck, Jonas Oldgren, John H. Alexander, Agneta Siegbahn, Lars Wallentin, Ziad Hijazi   +6 more
doaj   +1 more source

The Relationship Between Atrial Cardiopathy Biomarkers and Prognosis of Patients With Embolic Stroke of Undetermined Source

Frontiers in Cardiovascular Medicine, 2022
ObjectiveTo compare the proportion of atrial cardiopathy in patients with embolic stroke of undetermined source (ESUS) and other non-cardiac strokes, and to evaluate the prognostic value of atrial cardiopathy biomarkers in patients with ESUS.MethodsThis ...
Yuye Ning, Meng Wei, Wenfeng Song, Guogang Luo   +3 more
doaj   +1 more source