Results 41 to 50 of about 63,852 (318)

Programmed Exercise Attenuates Familial Hypertrophic Cardiomyopathy in Transgenic E22K Mice via Inhibition of PKC-α/NFAT Pathway

Frontiers in Cardiovascular Medicine, 2022
Familial hypertrophic cardiomyopathy (FHCM), an autosomal dominant disease, is caused by mutations in genes encoding cardiac sarcomeric proteins. E22K, a mutation in the myosin regulatory light chain sarcomere gene, is associated with the development of ...
Haiying Wang, Yuedong Lin, Ran Zhang, Yafen Chen, Wei Ji, Shenwei Li, Li Wang, Rubin Tan, Jinxiang Yuan   +8 more
doaj   +1 more source

Causal Effects of Hydrophilic Bile Acids on Carfilzomib‐Related Cardiovascular Events in Multiple Myeloma: A Mendelian Randomization Study

Clinical Pharmacology &Therapeutics, EarlyView.
Carfilzomib is highly effective in the treatment of multiple myeloma, but it has been associated with cardiovascular adverse events that impact patient outcomes. Our prior global metabolomic analyses indicated an association between hydrophilic bile acids and carfilzomib‐cardiotoxicity risk, although a causal relationship remained to be determined ...
Samia Shabnaz, Eric Farber‐Eger, Marwa Tantawy, Neyousha Shahisavandi, Timothy J. Garrett, Samuel M. Rubinstein, Michael G. Fradley, Mohammed E. Alomar, Danny DeAvila, Kenneth H Shain, R. Frank Cornell, Daniel Lenihan, Qing Lu, Quinn S Wells, Rachid C. Baz, Yan Gong   +15 more
wiley   +1 more source

Novel biomarkers for risk stratification in pulmonary arterial hypertension

ERJ Open Research, 2015
Risk stratification in pulmonary arterial hypertension (PAH) is paramount to identifying individuals at highest risk of death. So far, there are only limited parameters for prognostication in patients with PAH.
Thomas Zelniker, Lorenz Uhlmann, Sebastian Spaich, Jörg Friedrich, Michael R. Preusch, Franz J. Meyer, Hugo A. Katus, Evangelos Giannitsis   +7 more
doaj   +1 more source

Atrial fibrillation impairs the diagnostic performance of cardiac natriuretic peptides in dyspneic patients. results from the BACH Study (Biomarkers in ACute Heart Failure) [PDF]

, 2013
Objectives: The purpose of this study was to assess the impact of atrial fibrillation (AF) on the performance of mid-region amino terminal pro-atrial natriuretic peptide (MR-proANP) in comparison with the B-type peptides (BNP and NT-proBNP) for diagnosis
Anand I, Anker SD, Christenson R, Clopton P, Daniels LB, DI SOMMA, Salvatore, Filippatos GS, Hartmann O, Hogan C, Maisel A., Mockel M, Mueller C, Neath SX, Ng L, Nowak R, Peacock WF, Ponikowski P, Richards M, Shah K, Wu AH   +19 more
core   +1 more source

Progression and prognostic significance of electrocardiographic findings in patients with cardiac amyloidosis

ESC Heart Failure, Volume 12, Issue 2, Page 809-818, April 2025.
Abstract Aims This study aimed to evaluate the change of the main electrocardiographic (ECG) characteristics and their prognostic role across the main subtypes of cardiac amyloidosis [light‐chain amyloidosis (AL) and hereditary (ATTRv) and wild‐type transthyretin amyloidosis (ATTRwt)].
Alessia Argirò, Mattia Zampieri, Carlotta Mazzoni, Carlo Fumagalli, Michela Baccini, Alessandra Mattei, Alberto Cipriani, Laura De Michieli, Aldostefano Porcari, Gianfranco Sinagra, Marco Merlo, Giacomo Tini, Beatrice Musumeci, Domitilla Russo, Pier Filippo Vianello, Marco Canepa, Roberto Licordari, Gianluca di Bella, Claudio Rapezzi, Federico Perfetto, Francesco Cappelli   +20 more
wiley   +1 more source

Atrial natriuretic peptide and feeding activity patterns in rats

Brazilian Journal of Medical and Biological Research, 1997
This review presents historical data about atrial natriuretic peptide (ANP) from its discovery as an atrial natriuretic factor (ANF) to its role as an atrial natriuretic hormone (ANH).
Oliveira M.H.A., Antunes-Rodrigues J., Gutkowska J., Leal A.M.O., Elias L.L.K., Moreira A.C.   +5 more
doaj  

Natriuretic Peptides, Diagnostic and Prognostic Biomarkers [PDF]

, 2010
In humans, the natriuretic peptide family consists of three different types of peptides: atrial natriuretic peptide (synonym: atrial natriuretic factor), B-type natriuretic peptide (synonym: brain natriuretic peptide) and C-natriuretic peptide.1 ...
Rutten, J.H.W. (Joost)
core  

Estimated central blood volume in cirrhosis [PDF]

, 1992
The estimated central blood volume (i.e., blood volume in the heart cavities, lungs and central arterial tree) was determined by multiplying cardiac output by circulatory mean transit time in 19 patients with cirrhosis and compared with sympathetic ...
Arendt, Arroyo, Bendtsen, Bichet, Bichet, Bonkovsky, Bosch, Campbell, Christensen, Epstein, Gerbes, Gerbes, Gerbes, Gerbes, Goetz, Gossmann, Groszmann, Henriksen, Henriksen, Henriksen, Henriksen, Henriksen, Henriksen, Keller, Kopp, Kostreva, Lassen, Liebermann, Nicholls, Panos, Rector, Rector, Ring-Larsen, Rodriguez-Roisin, Rowell, Sagawa, Salerno, Schlant, Schrier, Sherlock   +39 more
core   +1 more source

Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.
Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu, Zhenbang Gu, Wengen Zhu, Shenghui Feng   +3 more
wiley   +1 more source

The Relationship Between Atrial Cardiopathy Biomarkers and Prognosis of Patients With Embolic Stroke of Undetermined Source

Frontiers in Cardiovascular Medicine, 2022
ObjectiveTo compare the proportion of atrial cardiopathy in patients with embolic stroke of undetermined source (ESUS) and other non-cardiac strokes, and to evaluate the prognostic value of atrial cardiopathy biomarkers in patients with ESUS.MethodsThis ...
Yuye Ning, Meng Wei, Wenfeng Song, Guogang Luo   +3 more
doaj   +1 more source