Results 1 to 10 of about 698,332 (299)

Usefulness of the Kyoto Classification Score for Prediction of Current Helicobacter pylori Infection [PDF]

The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2022
Background/Aims: Based on the Kyoto classification of gastritis, mucosal atrophy, endoscopic intestinal metaplasia, fold enlargement, nodularity, and diffuse redness may be associated with gastric cancer and Helicobacter pylori (H. pylori) infection.
Heejun Kang, Chul-Hyun Lim, Sukil Kim, Arum Choi, Jung-Hwan Oh   +4 more
doaj   +1 more source

Mitochondrial dysfunction: roles in skeletal muscle atrophy

Journal of Translational Medicine, 2023
Mitochondria play important roles in maintaining cellular homeostasis and skeletal muscle health, and damage to mitochondria can lead to a series of pathophysiological changes.
Xin Chen, Yi Ji, Ruiqi Liu, Xucheng Zhu, Kexin Wang, Xiaoming Yang, Boya Liu, Zihui Gao, Yan Huang, Yuntian Shen, Hua Liu, Hualin Sun   +11 more
semanticscholar   +1 more source

The Movement Disorder Society Criteria for the Diagnosis of Multiple System Atrophy

Movement Disorders, 2022
The second consensus criteria for the diagnosis of multiple system atrophy (MSA) are widely recognized as the reference standard for clinical research, but lack sensitivity to diagnose the disease at early stages.
G. Wenning, I. Stanković, L. Vignatelli, A. Fanciulli, G. Calandra-Buonaura, K. Seppi, J. Palma, W. Meissner, F. Krismer, D. Berg, P. Cortelli, R. Freeman, G. Halliday, Günter U. Höglinger, A. Lang, H. Ling, I. Litvan, P. Low, Y. Miki, J. Panicker, M. T. Pellecchia, N. Quinn, R. Sakakibara, M. Stamelou, E. Tolosa, S. Tsuji, T. Warner, W. Poewe, H. Kaufmann   +28 more
semanticscholar   +1 more source

Advances and limitations for the treatment of spinal muscular atrophy

BMC Pediatrics, 2022
Spinal muscular atrophy (5q-SMA; SMA), a genetic neuromuscular condition affecting spinal motor neurons, is caused by defects in both copies of the SMN1 gene that produces survival motor neuron (SMN) protein.
John W. Day, Kelly Howell, Amy Place, Kimberly Long, Jose Rossello, Nathalie Kertesz, George Nomikos   +6 more
doaj   +1 more source

Mesenchymal stromal cells ameliorate diabetes‐induced muscle atrophy through exosomes by enhancing AMPK/ULK1‐mediated autophagy

Journal of Cachexia, Sarcopenia and Muscle, 2023
Diabetes and obesity are associated with muscle atrophy that reduces life quality and lacks effective treatment. Mesenchymal stromal cell (MSC)‐based therapy can ameliorate high fat‐diet (HFD) and immobilization (IM)‐induced muscle atrophy in mice ...
Jia Song, Jidong Liu, C. Cui, Huiqing Hu, N. Zang, Mengmeng Yang, Jingwen Yang, Ying Zou, Jinquan Li, Lingshu Wang, Qin He, Xinghong Guo, Ruxing Zhao, Fei Yan, Fuqiang Liu, X. Hou, Zheng Sun, Li Chen   +17 more
semanticscholar   +1 more source

Reliability and Validity of an Ultrasound-Based Protocol for Measurement of Quadriceps Muscle Thickness in Children

Frontiers in Physiology, 2022
Introduction and aims: Accurate determination of skeletal muscle size is of great importance in multiple settings including resistance exercise, aging, disease, and disuse.
Emil Rydell Högelin, Emil Rydell Högelin, Kajsa Thulin, Kajsa Thulin, Ferdinand von Walden, Ferdinand von Walden, Lotta Fornander, Lotta Fornander, Piotr Michno, Piotr Michno, Björn Alkner, Björn Alkner   +11 more
doaj   +1 more source

Preliminary Observations on Skeletal Muscle Adaptation and Plasticity in Homer 2^-/- Mice

Metabolites, 2021
Homer represents a diversified family of scaffold and transduction proteins made up of several isoforms. Here, we present preliminary observations on skeletal muscle adaptation and plasticity in a transgenic model of Homer 2-/- mouse using a multifaceted
Paola Lorenzon, Sandra Furlan, Barbara Ravara, Alessandra Bosutti, Gabriele Massaria, Annalisa Bernareggi, Marina Sciancalepore, Gabor Trautmann, Katharina Block, Dieter Blottner, Paul F. Worley, Sandra Zampieri, Michele Salanova, Pompeo Volpe   +13 more
doaj   +1 more source

Mechanisms of muscle atrophy and hypertrophy: implications in health and disease

Nature Communications, 2021
Skeletal muscle is the protein reservoir of our body and an important regulator of glucose and lipid homeostasis. Consequently, the growth or the loss of muscle mass can influence general metabolism, locomotion, eating and respiration.
R. Sartori, V. Romanello, M. Sandri
semanticscholar   +1 more source

Changes in Behaviour and Proxies of Physiology Suggest Individual Variation in the Building of Migratory Phenotypes in Preparation for Long-Distance Flights

Frontiers in Ecology and Evolution, 2022
Long-distance migration in birds is a complex syndrome that involves high energy costs and, in some species, substantial physiological re-organisation.
Tess Handby, Julia Slezacek, Sara Lupi, Kendrew Colhoun, Xavier A. Harrison, Stuart Bearhop   +5 more
doaj   +1 more source

Risdiplam in Type 1 Spinal Muscular Atrophy.

New England Journal of Medicine, 2021
BACKGROUND Type 1 spinal muscular atrophy is a rare, progressive neuromuscular disease that is caused by low levels of functional survival of motor neuron (SMN) protein. Risdiplam is an orally administered, small molecule that modifies SMN2 pre-messenger
G. Baranello, B. Darras, J. Day, N. Deconinck, A. Klein, R. Masson, E. Mercuri, K. Rose, M. El-Khairi, M. Gerber, K. Gorni, O. Khwaja, Heidemarie Kletzl, R. Scalco, T. Seabrook, P. Fontoura, L. Servais   +16 more
semanticscholar   +1 more source