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Decomposing the effect of normal aging and Alzheimer's disease in brain morphological changes via learned aging templates. [PDF]
Sci Rep, 2023 Alzheimer's Disease and normal aging are both characterized by brain atrophy. The question of whether AD-related brain atrophy represents accelerated aging or a neurodegeneration process distinct from that in normal aging remains unresolved. Moreover, precisely disentangling AD-related brain atrophy from normal aging in a clinical context is complex ...
Fu J, Ferreira D, Smedby Ö, Moreno R.
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Frontiers in Bioengineering and Biotechnology, 2021 Mesenchymal stromal cells (MSCs) are multipotent cells found in different tissues: bone marrow, peripheral blood, adipose tissues, skeletal muscle, perinatal tissues, and dental pulp.
Martina Sandonà +8 more
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Репродуктивная эндокринология, 2021 Cervical cancer (CC) screening is a major component of secondary prevention of CC and involves screening all women at risk of developing this disease, most of whom are asymptomatic.
O.A. Burka +3 more
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Advances and limitations for the treatment of spinal muscular atrophy
BMC Pediatrics, 2022 Spinal muscular atrophy (5q-SMA; SMA), a genetic neuromuscular condition affecting spinal motor neurons, is caused by defects in both copies of the SMN1 gene that produces survival motor neuron (SMN) protein.
John W. Day +6 more
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Frontiers in Cell and Developmental Biology, 2022 Germinal matrix-intraventricular hemorrhage (GM-IVH) is the most frequent intracranial hemorrhage in the preterm infant (PT). Long-term GM-IVH-associated sequelae include cerebral palsy, sensory and motor impairment, learning disabilities, or ...
Pilar Alves-Martinez +19 more
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Muscle metabolic stress determines cancer cachexia severity in mice
Frontiers in Physiology, 2022 Objectives: To determine the metabolic effects of cancer-conditioned media on myotube metabolism and to understand whether the variability of these effects is associated with cancer cachexia progression.Materials and methods: We established single-cell ...
Christiano Alves +3 more
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Dermatology Online Journal, 2013 We report the case of a 44-year-old woman with a one-year history of en coup de sabre morphea and progressive hemifacial atrophy with ipsilateral hemifacial neuralgia, migraine, and contralateral neurologic abnormalities. While rare, Parry-Romberg syndrome typically presents in the first or second decade of life; this patient's case is unusual in that ...
Vedvyas, Chetan, Urbanek, Richard W
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Cerebellar atrophy with long-term phenytoin (PHT) use: Case report [PDF]
Romanian Journal of Neurology, 2017 Cerebellar atrophy can be found with long-term phenytoin (PHT) use or acute phenytoin intoxication. PHT may cause cerebellar symptoms, such as nystagmus, diplopia, dysarthria and ataxia. Clinical manifestations may be persistent. We report a case of a 41-
Jamir P. Rissardo +2 more
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Withaferin A and Ovarian Cancer Antagonistically Regulate Skeletal Muscle Mass
Frontiers in Cell and Developmental Biology, 2021 Cachexia is a complex wasting syndrome that overwhelmingly affects the majority of late-stage cancer patients. Additionally, there are currently no efficacious therapeutic agents to treat the muscle atrophy induced by the cancer.
Alex R. Straughn +3 more
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Is neutral zone, patients comfort zone? A feedback review
Journal of Pharmacy and Bioallied Sciences, 2020 The technique of neutral zone is useful. It is the convergence of many concepts and ideas into a feasible and functional method. The technique aims to build a denture in accordance with the underlying oral structures that are formed by muscle function ...
V Beenu +5 more
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