Results 1 to 10 of about 738,883 (337)

N-Chlorotaurine Reduces the Lung and Systemic Inflammation in LPS-Induced Pneumonia in High Fat Diet-Induced Obese Mice

Metabolites, 2022
Lung infection can evoke pulmonary and systemic inflammation, which is associated with systemic severe symptoms, such as skeletal muscle wasting. While N-chlorotaurine (also known as taurine chloramine; TauCl) has anti-inflammatory effects in cells, its ...
Nguyen Khanh Hoang, Eiji Maegawa, Shigeru Murakami, Stephen W. Schaffer, Takashi Ito   +4 more
doaj   +1 more source

Determining the role of tumor-derived leukemia inhibitory factor in cancer cachexia using a genetic approach [PDF]

, 2018
Cachexia is a multifactorial metabolic wasting syndrome that affects a large percentage of cancer patients and results in the involuntary loss of skeletal muscle and adipose tissue.
Ganey, John
core  

Metabolic Pathways and Ion Channels Involved in Skeletal Muscle Atrophy: A Starting Point for Potential Therapeutic Strategies

Cells, 2022
Skeletal muscle tissue has the important function of supporting and defending the organism. It is the largest apparatus in the human body, and its function is important for contraction and movements.
Ileana Canfora, Nancy Tarantino, Sabata Pierno   +2 more
doaj   +1 more source

Normal aging and Alzheimer's disease : hippocampal and episodic memory differences [PDF]

, 2016
Alzheimer’s Disease (AD) and normal aging (NA) are characterized by structural brain changes as well as cognitive changes that appear over the lifespan.
Marnell, Ashley Michele
core   +1 more source

Ultrasound Evaluation of Testicular Volume in Patients with Testicular Microlithiasis

Ultrasound International Open, 2018
Purpose Ultrasonography is a useful tool to measure testicular volume. According to the European Society of Urogenital Radiology, the combination of testicular atrophy and testicular microlithiasis (TML) is a risk factor for testicular cancer ...
Malene Roland Pedersen, Palle Jørn Sloth Osther, Søren Rafael Rafaelsen   +2 more
doaj   +1 more source

Qualitative and Quantitative Comparison of Hippocampal Volumetric Software Applications: Do All Roads Lead to Rome?

Biomedicines, 2022
Brain volumetric software is increasingly suggested for clinical routine. The present study quantifies the agreement across different software applications.
Stephanie Mangesius, Lukas Haider, Lukas Lenhart, Ruth Steiger, Ferran Prados Carrasco, Christoph Scherfler, Elke R. Gizewski   +6 more
doaj   +1 more source

Prostatic atrophy: clinicopathological significance

International Brazilian Journal of Urology, 2010
Prostatic atrophy is a benign lesion that may mimic adenocarcinoma histologically and on imaging. It is more frequent in the peripheral zone and has gained importance with the increasing use of needle biopsies.
Athanase Billis
doaj   +1 more source

PD-1 Alleviates Cisplatin-Induced Muscle Atrophy by Regulating Inflammation and Oxidative Stress

Antioxidants, 2022
Skeletal muscle atrophy is an important characteristic of cachexia, which can be induced by chemotherapy and significantly contributes to functional muscle impairment.
Xiaoguang Liu, Miaomiao Xu, Yang Yu, Yingjie Chen, Xinyu Weng, Lin Zhu   +5 more
doaj   +1 more source

Kufor-Rakeb syndrome, pallido-pyramidal degeneration with supranuclear upgaze paresis and dementia, maps to 1p36 [PDF]

, 2001
Kufor-Rakeb syndrome is an autosomal recessive nigro-striatal-pallidal-pyramidal neurodegeneration. The onset is in the teenage years with clinical features of Parkinson’s disease plus spasticity, supranuclear upgaze paresis, and dementia.
Al-Din, A., Bond, J., Crow, Y., Hampshire, D.J., Mubaidin, A., Roberts, E., Woods, C.G., Wriekat, A.L.   +7 more
core   +2 more sources

mTOR as a Key Regulator in Maintaining Skeletal Muscle Mass

Frontiers in Physiology, 2017
Maintenance of skeletal muscle mass is regulated by the balance between anabolic and catabolic processes. Mammalian target of rapamycin (mTOR) is an evolutionarily conserved serine/threonine kinase, and is known to play vital roles in protein synthesis ...
Mee-Sup Yoon
doaj   +1 more source