Results 21 to 30 of about 698,332 (299)

A Rare Case of Familial Progressive Ataxia with Palatal Tremors [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2022
A 25-year-old female patient presented with insidious onset progressive difficulties of gait and balance. Onset of these symptoms first appeared nine years prior and evolved to include changes in speech, increased occurrence of falls and spastic ...
Abhilash Mishra   +4 more
doaj   +1 more source

Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy

open access: yesNature Communications, 2021
The thrombospondin (Thbs) family of secreted matricellular proteins are stress- and injury-induced mediators of cellular attachment dynamics and extracellular matrix protein production.
D. Vanhoutte   +8 more
semanticscholar   +1 more source

Sodium deoxycholate - mechanism of action, application technique, indications, and adverse effects [PDF]

open access: yesSurgical & Cosmetic Dermatology
Techniques for removing adipose tissue are always of great interest, and among many described, the applications of sodium deoxycholate (DS) or deoxycholic acid, known as intralipotherapy, have stood out in recent years, following approval by the FDA for ...
Marisa Gonzaga da Cunha   +4 more
doaj   +1 more source

Prospective longitudinal atrophy in Alzheimer’s disease correlates with the intensity and topography of baseline tau-PET

open access: yesScience Translational Medicine, 2020
Tau imaging with [18F]flortaucipir predicts the severity and topography of subsequent MRI cortical atrophy in patients with Alzheimer’s disease. Predictive PET Understanding the dynamic of the two major hallmark of Alzheimer’s disease (AD), tau protein ...
R. La Joie   +21 more
semanticscholar   +1 more source

Biomechanical evaluation of custom-made short implants with wing retention applied in severe atrophic maxillary posterior region restoration: A three-dimensional finite element analysis

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Severe bone atrophy in the maxillary posterior region poses a big challenge to implant restoration. Digitally designed and customized short implants with wing retention provide a safer and minimally invasive implant restoration scheme in such ...
Zhen Yang   +11 more
doaj   +1 more source

Polyphenols and Their Effects on Muscle Atrophy and Muscle Health

open access: yesMolecules, 2021
Skeletal muscle atrophy is the decrease in muscle mass and strength caused by reduced protein synthesis/accelerated protein degradation. Various conditions, such as denervation, disuse, aging, chronic diseases, heart disease, obstructive lung disease ...
T. Nikawa, Anayt Ulla, Iori Sakakibara
semanticscholar   +1 more source

LGMD D2 TNPO3-Related: From Clinical Spectrum to Pathogenetic Mechanism

open access: yesFrontiers in Neurology, 2022
Limb-girdle muscular dystrophies (LGMDs) are clinically and genetically heterogeneous diseases presenting with a wide clinical spectrum. Autosomal dominant LGMDs represent about 10–15% of LGMDs and include disorders due to defects of DNAJB6, transportin ...
Roberta Costa   +8 more
doaj   +1 more source

MAGNIMS consensus recommendations on the use of brain and spinal cord atrophy measures in clinical practice

open access: yesNature Reviews Neurology, 2020
Early evaluation of treatment response and prediction of disease evolution are key issues in the management of people with multiple sclerosis (MS). In the past 20 years, MRI has become the most useful paraclinical tool in both situations and is used ...
J. Sastre-Garriga   +20 more
semanticscholar   +1 more source

Supraphysiologic Administration of GDF11 Induces Cachexia in Part by Upregulating GDF15

open access: yesCell Reports, 2018
Summary: The age-related effects of GDF11 have been a subject of controversy. Here, we find that elevated GDF11 causes signs of cachexia in mice: reduced food intake, body weight, and muscle mass.
Juli E. Jones   +10 more
doaj   +1 more source

Discussion of Breast Atrophy in One Case

open access: yesEuropean Journal of Breast Health, 2013
Breast atrophy can occur due to various reasons and it may be a cosmetic problem for women. The main etiological factors are hormonal insufficiency, hormonal axis suppression, virilizing tumors, and the use of anabolic hormones.
Tufan Egeli   +3 more
doaj   +1 more source

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