Results 21 to 30 of about 728,913 (287)
Cells, 2020 Transforming Growth Factor β (TGF-β) is involved in fibrosis as well as the regulation of muscle mass, and contributes to the progressive pathology of muscle wasting disorders. However, little is known regarding the time-dependent signalling of
Michèle M. G. Hillege +5 more
doaj +1 more source
A key role for leukemia inhibitory factor in C26 cancer cachexia [PDF]
, 2015 Cachexia is an exacerbating event in many types of cancer that is strongly associated with a poor prognosis. We have identified cytokine, signaling, and transcription factors that are required for cachexia in the mouse C26 colon carcinoma model of cancer.
Jackman, Robert W. +2 more
core +1 more source
Molecular Therapy: Nucleic Acids, 2022 FilaminC (Flnc) is a member of the actin binding protein family, which is preferentially expressed in the cardiac and skeletal muscle tissues. Although it is known to interact with proteins associated with myofibrillar myopathy, its unique role in ...
Shunshun Han +12 more
doaj +1 more source
Gigantic Stomach: A Rare Manifestation of Duchenne Muscular Dystrophy [PDF]
, 2019 Duchenne muscular dystrophy (DMD) is characterized by degeneration and atrophy of skeletal, cardiac, and smooth muscles after a latent period of apparently normal development and function. The gastrointestinal manifestations start in the second decade of
Dhaliwal, Amaninder +4 more
core +2 more sources
Frontiers in Neurology, 2020 Cerebellar damage occurs frequently in multiple sclerosis (MS) patients, with a wide exhibition of symptoms particularly as impairments of balance and gait. Recent studies implementing new postprocessing magnetic resonance imaging (MRI) techniques showed
Serena Ruggieri +10 more
doaj +1 more source
Single cell analysis reveals the involvement of the long non-coding RNA Pvt1 in the modulation of muscle atrophy and mitochondrial network [PDF]
, 2019 Long non-coding RNAs (lncRNAs) are emerging as important players in the regulation of several aspects of cellular biology. For a better comprehension of their function, it is fundamental to determine their tissue or cell specificity and to identify their
Alessio, Enrico +13 more
core +1 more source
The value of hippocampal and temporal horn volumes and rates of change in predicting future conversion to AD. [PDF]
, 2012 Hippocampal pathology occurs early in Alzheimer disease (AD), and atrophy, measured by volumes and volume changes, may predict which subjects will develop AD.
ADNI investigators +5 more
core +1 more source
The Effect of Chronic Exposure with Imidacloprid Insecticide on Fertility in Mature Male Rats [PDF]
International Journal of Fertility and Sterility, 2010 Background This study was conducted to evaluate the effect of chronic exposure to imidacloprid (IM) insecticide on male testicular tissue, sperm morphology and testosterone levels in the serum of mature male rats.
Golamreza Najafi +4 more
doaj +1 more source
Medical management of hereditary optic neuropathies. [PDF]
, 2014 Hereditary optic neuropathies are diseases affecting the optic nerve. The most common are mitochondrial hereditary optic neuropathies, i.e., the maternally inherited Leber's hereditary optic neuropathy (LHON) and dominant optic atrophy (DOA).
Barboni, Piero +4 more
core +1 more source
Obesity Augments Glucocorticoid-Dependent Muscle Atrophy in Male C57BL/6J Mice
Biomedicines, 2020 Glucocorticoids promote muscle atrophy by inducing a class of proteins called atrogenes, resulting in reductions in muscle size and strength.
Laura C. Gunder +6 more
doaj +1 more source