Results 41 to 50 of about 655,529 (373)
Archives of Pediatrics & Adolescent Medicine, 1912 The term "atrophy of infants" was formerly used to designate a disease sui generis . It was characterized clinically by the fact that children, who had developed well up to a certain time, gradually began to fail and eventually died, presenting the picture of a progressive and often extreme grade of emaciation.
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JAMA: The Journal of the American Medical Association, 1901 It may be sometimes quite impossible to discover the cause of disease, and it is not always easy to determine whether a lesion is dependent upon some other morbid process, or of primary origin. I have hesitated to believe it possible for atrophy of the retina to come on as a primary condition, without any discoverable preceding inflammation, or even ...
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A deformation-based morphometry framework for disentangling Alzheimer's disease from normal aging using learned normal aging templates [PDF]
, 2023 Alzheimer's Disease and normal aging are both characterized by brain atrophy. The question of whether AD-related brain atrophy represents accelerated aging or a neurodegeneration process distinct from that in normal aging remains unresolved. Moreover, precisely disentangling AD-related brain atrophy from normal aging in a clinical context is complex ...
arxiv +1 more source
Simultaneous column-based deep learning progression analysis of atrophy associated with AMD in longitudinal OCT studies [PDF]
arXiv, 2023 Purpose: Disease progression of retinal atrophy associated with AMD requires the accurate quantification of the retinal atrophy changes on longitudinal OCT studies. It is based on finding, comparing, and delineating subtle atrophy changes on consecutive pairs (prior and current) of unregistered OCT scans.
arxiv
Noninvasive optical estimation of CSF thickness for brain-atrophy monitoring [PDF]
Biomedical Optics Express 9 (2018) 4094-4112, 2018 Dementia disorders are increasingly becoming sources of a broad range of problems, strongly interfering with normal daily tasks of a growing number of individuals. Such neurodegenerative diseases are often accompanied with progressive brain atrophy that, at late stages, leads to drastically reduced brain dimensions.
arxiv +1 more source
Nature Reviews Neurology, 2020 Early evaluation of treatment response and prediction of disease evolution are key issues in the management of people with multiple sclerosis (MS). In the past 20 years, MRI has become the most useful paraclinical tool in both situations and is used ...
J. Sastre-Garriga +20 more
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Cancer cell-derived exosomal miR-425-3p induces white adipocyte atrophy
Adipocyte, 2022 White adipose tissue wasting plays a critical role in the development and progression of cancer cachexia. However, the mechanism behind the loss of adipose tissue remains ill-defined.
Anwen Liu +4 more
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High-dimensional single-index Bayesian modeling of brain atrophy [PDF]
Bayesian Analysis (2019), 2017 We propose a model of brain atrophy as a function of high-dimensional genetic information and low dimensional covariates such as gender, age, APOE gene, and disease status. A nonparametric single-index Bayesian model of high dimension is proposed to model the relationship with B-spline series prior on the unknown functions and Dirichlet process scale ...
arxiv +1 more source
Self-Supervised CSF Inpainting with Synthetic Atrophy for Improved Accuracy Validation of Cortical Surface Analyses [PDF]
arXiv, 2023 Accuracy validation of cortical thickness measurement is a difficult problem due to the lack of ground truth data. To address this need, many methods have been developed to synthetically induce gray matter (GM) atrophy in an MRI via deformable registration, creating a set of images with known changes in cortical thickness.
arxiv