Results 41 to 50 of about 402,338 (287)

Determining the role of tumor-derived leukemia inhibitory factor in cancer cachexia using a genetic approach [PDF]

, 2018
Cachexia is a multifactorial metabolic wasting syndrome that affects a large percentage of cancer patients and results in the involuntary loss of skeletal muscle and adipose tissue.
Ganey, John
core  

Treatment algorithm for infants diagnosed with spinal muscular atrophy through newborn screening [PDF]

, 2018
Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by the degeneration of alpha motor neurons in the spinal cord, leading to muscular atrophy.
Connolly, Anne, Crawford, Thomas O, Darras, Basil, Day, John, Finkel, Richard, Glascock, Jacqueline, Haidet-Phillips, Amanda, Howell, R. Rodney, Jarecki, Jill, Ker, Douglas, Klinger, Katherine, Kuntz, Nancy, Prior, Thomas, Sampson, Jacinda, Shieh, Perry B   +14 more
core   +2 more sources

Isolated Subtle Neurological Abnormalities in Mild Cognitive Impairment Types [PDF]

, 2020
Background: Isolated, subtle neurological abnormalities (ISNA) are commonly seen in aging and have been related to cerebral small vessel disease (SVD) and subcortical atrophy in neurologically and cognitively healthy aging subjects.
Azzarello, Delia, Camarda, Cecilia, Camarda, Rosolino, Cilluffo, Giovanna, Grassedonio, Emanuele, Pipia, Carmela, Sottile, Gianluca, Torelli, Paola   +7 more
core   +1 more source

Impact of α-synuclein fibril structure on seeding activity in experimental models of Parkinson’s disease

npj Parkinson's Disease
The central pathogenesis of Parkinson’s disease involves the misfolding and aggregation of α-synuclein (α-syn). There is a widespread belief that α-syn can propagate in a prion-like manner, and α-syn preformed fibrils (PFFs) have been widely used to ...
Junichiro Ohira, Masanori Sawamura, Kenichi Kawano, Risa Sato, Tomoyuki Taguchi, Tomoyuki Ishimoto, Jun Ueda, Masashi Ikuno, Shu-ichi Matsuzawa, Katsumi Matsuzaki, Ryosuke Takahashi, Hodaka Yamakado   +11 more
doaj   +1 more source

Inorganic Arsenic Exposure Decreases Muscle Mass and Enhances Denervation-Induced Muscle Atrophy in Mice

Molecules, 2020
Arsenic is a toxic metalloid. Infants with a low birth-weight have been observed in areas with high-level arsenic in drinking water ranging from 463 to 1025 μg/L.
Chang-Mu Chen, Min-Ni Chung, Chen-Yuan Chiu, Shing-Hwa Liu, Kuo-Cheng Lan   +4 more
doaj   +1 more source

Two distinct aetiologies of cardia cancer, evidence from premorbid serological markers of gastric atrophy and Helicobacter pylori status [PDF]

, 2007
Background: Non-cardia gastric adenocarcinoma is positively associated with Helicobacter pylori infection and atrophic gastritis. The role of H pylori infection and atrophic gastritis in cardia cancer is unclear.
Aase, S., Derakhshan, M.H., Fyfe, V., Hansen, S., Jellum, E., McColl, K.E.L., Melby, K.K., Vollset, S.E.   +7 more
core   +2 more sources

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Comparative Evaluation of Pattern of Anterior Loop of Mandibular Canal in Dentulous and Edentulous Patients Using Cone Beam Computed Tomography: A Cross-Sectional Study

Journal of Indian Academy of Oral Medicine and Radiology
Background: Previous literature has discussed the prevalence of various patterns of anterior loops in male and female populations. We rarely encounter studies examining the patterns of anterior loops in dentulous and edentulous patients.
Kalyani Khairnar, Chetan Bhadage, Ajay Bhoosreddy, Madhura Barve   +3 more
doaj   +1 more source

Volumetric Assessment of Extratemporal Structures in Patients With Temporal Lobe Epilepsy

International Clinical Neuroscience Journal, 2022
Background: We assessed the presence of brain volume loss in the extratemporal structures in patients with temporal lobe epilepsy (TLE). The associations between brain volume loss in these structures and epilepsy duration, magnetic resonance imaging (MRI)
Marjan Asadollahi, Elham Rahimian, Ali Akbar Asadi-Pooya, Majid Tahsini, Hans-Jürgen Huppertz, Nayyereh Akbari, Leila Simani   +6 more
doaj   +1 more source

Rates of lobar atrophy in asymptomatic MAPT mutation carriers. [PDF]

, 2019
IntroductionThe aim of this study was to investigate the rates of lobar atrophy in the asymptomatic microtubule-associated protein tau (MAPT) mutation carriers.MethodsMAPT mutation carriers (n = 14; 10 asymptomatic, 4 converters from ...
Boeve, Bradley F, Boxer, Adam L, Brushaber, Danielle, Chen, Qin, Dheel, Christina, Fields, Julie, Forsberg, Leah, Gavrilova, Ralitza, Gearhart, Debra, Graff-Radford, Jonathan, Graff-Radford, Neill R, Jack, Clifford R, Jones, David T, Kantarci, Kejal, Knopman, David S, Kremers, Walter K, Lapid, Maria, LEFFTDS Consortium, Lesnick, Timothy G, Rademakers, Rosa, Rosen, Howie, Senjem, Matthew, Syrjanen, Jeremy, Tosakulwong, Nirubol, Wszolek, Zbigniew K   +24 more
core   +2 more sources