Results 111 to 120 of about 84,826 (242)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Change in negative attention bias mediates the association between attention bias modification training and depression symptom improvement. [PDF]

J Consult Clin Psychol, 2021
Beevers CG, Hsu KJ, Schnyer DM, Smits JAJ, Shumake J.   +4 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Increased attention to climate change mitigation approaches leads to lower levels of climate anxiety

Discover Psychology
Climate change is a significant threat to both ecosystems and human mental health. Rising awareness of the threats posed by climate change is linked to increased psychological distress, or climate anxiety.
Joshua M. Carlson
doaj   +1 more source

Brief Repeated Attention Training for Psychological Distress: Findings from Two Experiments

Behavioral Sciences
Psychological distress is understood to be maintained by attention. We performed two experiments examining the impact of attention training (AT) on psychological distress symptoms. Experiment one (N = 336) investigated what effects might be detected in a
David Skvarc, Shannon Hyder, Laetitia Leary, Shahni Watts, Marcus Seecamp, Lewis Burns, Alexa Hayley   +6 more
doaj   +1 more source

Efficacy of attention bias modification training for depressed adults: a randomized clinical trial. [PDF]

Psychol Med, 2022
Hsu KJ, Shumake J, Caffey K, Risom S, Labrada J, Smits JAJ, Schnyer DM, Beevers CG.   +7 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Effect of internet-based attention bias modification on the anxiety of Japanese workers: A randomized controlled trial. [PDF]

J Occup Health, 2021
Tayama J, Shimazu A, Ogawa S, Nakaya N.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Attentional bias modification and attention control training in PTSD: a systematic review and meta-analysis

Therapeutic Advances in Psychopharmacology
Background: Cognitive models of post-traumatic stress disorder (PTSD) highlighted the effect of maladaptive cognitive processing in the development and maintenance of PTSD.
Fan Zhang, Chenwei Huang, Wenjie Yan, Hui Ouyang, Weizhi Liu   +4 more
doaj   +1 more source