Results 31 to 40 of about 49,586 (211)

On the annihilators and attached primes of top local cohomology modules [PDF]

open access: yes, 2014
Let \frak a be an ideal of a commutative Noetherian ring R and M a finitely generated R-module. It is shown that {\rm Ann}_R(H_{\frak a}^{{\dim M}({\frak a}, M)}(M))= {\rm Ann}_R(M/T_R({\frak a}, M)), where T_R({\frak a}, M) is the largest submodule of M
Atazadeh, Ali   +2 more
core   +2 more sources

Models of incremental concept formation [PDF]

open access: yes, 1988
Given a set of observations, humans acquire concepts that organize those observations and use them in classifying future experiences. This type of concept formation can occur in the absence of a tutor and it can take place despite irrelevant and ...
Fisher, Douglas   +2 more
core   +1 more source

Systemic ATTR-amyloidosis, a Rare Form of Internal Organ Damage

open access: yesРациональная фармакотерапия в кардиологии, 2019
The article presents the case report of a rare hereditary form of systemic ATTR-amyloidosis in Russian patient with a discussion of approaches to the diagnosis and treatment of this form, also based on the own experience in the management of such ...
V. V. Rameev   +12 more
doaj   +1 more source

Therapeutic Efficacy and Safety Profile of Eplontersen in Hereditary Transthyretin-Mediated Amyloidosis: A Systematic Review. [PDF]

open access: yesHealth Sci Rep
ABSTRACT Background Hereditary transthyretin‐mediated amyloidosis (hATTR) is a disorder that affects several body systems and can result in life‐threatening conditions like cardiomyopathy and polyneuropathy. For treatment of hATTR in the new medical realm, there is a breakthrough discovery of a medicine called Eplontersen, which targets the underlying ...
Patel ZV   +8 more
europepmc   +2 more sources

Making serine integrases work for us [PDF]

open access: yes, 2017
DNA site-specific recombinases are enzymes (often associated with mobile DNA elements) that catalyse breaking and rejoining of DNA strands at specific points, thereby bringing about precise genetic rearrangements.
Stark, W. Marshall
core   +1 more source

Recombinational cloning with plant gateway vectors [PDF]

open access: yes, 2007
International ...
Karimi, Mansour   +2 more
core   +3 more sources

Prevalence of transthyretin amyloidosis among heart failure patients with preserved ejection fraction in Japan

open access: yesESC Heart Failure, 2023
Aims Heart failure with preserved ejection fraction (HFpEF), which is caused by wide various conditions, has become a major public health problem. Transthyretin amyloid cardiomyopathy (ATTR‐CM), which is thought to be an underdiagnosed disease, can cause
Takanori Naito   +15 more
doaj   +1 more source

Structural basis for transthyretin amyloid formation in vitreous body of the eye

open access: yesNature Communications, 2021
Systemic ATTR amyloidosis causes the abnormal accumulation of ATTR fibrils formed from the human plasma protein transthyretin (TTR) in multiple organs including the eye.
Irina Iakovleva   +5 more
doaj   +1 more source

An Empirical Study and Analysis of Generalized Zero-Shot Learning for Object Recognition in the Wild

open access: yes, 2016
Zero-shot learning (ZSL) methods have been studied in the unrealistic setting where test data are assumed to come from unseen classes only. In this paper, we advocate studying the problem of generalized zero-shot learning (GZSL) where the test data's ...
Changpinyo, Soravit   +3 more
core   +1 more source

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