Results 61 to 70 of about 17,377 (218)

Transthyretin amyloid cardiomyopathy in aortic stenosis patients scheduled for transcatheter aortic valve implantation

ESC Heart Failure
Aims The prevalences of aortic stenosis (AS) and transthyretin amyloid cardiomyopathy (ATTR‐CM) increase with age. Identification of occult ATTR‐CM in patients with AS can help explain out‐of‐proportion myocardial dysfunction, aid in prognostication and ...
Margrethe Flesvig Holt, August Flø, Esra Kaya, Sophie Foss Kløve, Hege Martinsen, Kristine Amlie, Petter Storsten, Thomas Misje Mathiisen, Kristoffer Russell, Christian Hesbø Eek, Helge Skulstad, Melinda Raki, Lars Gullestad, Anders Hodt, Einar Gude, Kaspar Broch   +15 more
doaj   +1 more source

Plasmin activity promotes amyloid deposition in a transgenic model of human transthyretin amyloidosis

Nature Communications, 2021
ATTR amyloidosis causes heart failure through the accumulation of misfolded transthyretin in cardiac muscle. Here the authors report a mouse model of ATTR amyloidosis and demonstrate the involvement of protease activity in ATTR amyloid deposition.
Ivana Slamova, Rozita Adib, Stephan Ellmerich, Michal R. Golos, Janet A. Gilbertson, Nicola Botcher, Diana Canetti, Graham W. Taylor, Nigel Rendell, Glenys A. Tennent, Guglielmo Verona, Riccardo Porcari, P. Patrizia Mangione, Julian D. Gillmore, Mark B. Pepys, Vittorio Bellotti, Philip N. Hawkins, Raya Al-Shawi, J. Paul Simons   +18 more
doaj   +1 more source

Generating Compressed Counterfactual Hard Negative Samples for Graph Contrastive Learning

CAAI Transactions on Intelligence Technology, EarlyView.
ABSTRACT Graph contrastive learning (GCL) relies on acquiring high‐quality positive and negative samples to learn the structural semantics of the input graph. Previous approaches typically sampled negative samples from the same training batch or an irrelevant external graph.
Haoran Yang, Hongxu Chen, Xiangyu Zhao, Sixiao Zhang, Xiangguo Sun, Qian Li, Hongzhi Yin, Guandong Xu   +7 more
wiley   +1 more source

Black Accountants' Pursuit of Partnership La quête de l'accession au statut d'associé des comptables de race noire

Contemporary Accounting Research, EarlyView.
ABSTRACT Recent AICPA surveys indicate disproportionate attrition among Black professionals attaining partnership in US public accounting firms, underscoring the need to better understand their experiences. Despite repeated calls for examination, understanding of these experiences remains limited, partly due to the difficulty in accessing the few Black
Jennifer Joe, Eldar Maksymov, Kerri‐Ann Sanderson   +2 more
wiley   +1 more source

ATTR-CM patients demographic characteristics.

ObjectivesTo identify and describe the profile of potential transthyretin cardiac amyloidosis (ATTR-CM) cases in the Brazilian public health system (SUS), using a predictive machine learning (ML) model.MethodsThis was a retrospective descriptive database
Fabio Fernandes (3386423), Isabella Zuppo Laper (17972784), Marcus Vinicius Simões (5224412), Claudenice Leite Bertoli de Souza (17972790), Ariane de Jesus Lopes de Abreu (14425084), Rafaela Vansan Ferreira (14425090), Edileide de Barros Correia (17972793), Guilherme Silva Julian (8520117), Cecilia Camacho-Hubner (17972787)   +8 more
core   +1 more source

Electrophysiologial demyelinating features in hereditary ATTR amyloidosis (遺伝性ATTRアミロイド―シスにおける電気生理学的脱髄所見） [PDF]

, 2019
信州大学(Shinshu university)博士（医学）雑誌に発表。AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS. 26(1):15-23 (2019); doi:10.1080/13506129.2018.1564903.Thesis大橋　信彦. Electrophysiologial demyelinating features in hereditary ATTR amyloidosis (遺伝性ATTRアミロイド―シスにおける電気生理学的脱髄所見）.
大橋, 信彦
core   +1 more source

Six-minute walk test as clinical end point in cardiomyopathy clinical trials, including ATTR-CM: a systematic literature review

Journal of Comparative Effectiveness Research
Aim: The six-minute walk test (6MWT) is a common measure of functional capacity in patients with heart failure (HF). Primary clinical study end points in cardiomyopathy (CM) trials, including transthyretin-mediated amyloidosis with CM (ATTR-CM), are ...
Jose Nativi-Nicolau, Ali Yilmaz, Noel Dasgupta, Richard Macey, James Cochrane, Judith Peatman, Catherine Summers, Jennifer Luth, Ronald Zolty   +8 more
doaj   +1 more source

A Comparative User Study on Control‐Flow Visualizations of Event Log Data

Computer Graphics Forum, EarlyView.
This paper compares seven commonly used control‐flow visualizations using a formal user study with 48 participants. Directly‐Follows Graphs (DFGs), Petri nets, Business Process Model and Notations, Process trees, variant timelines, Icicle plots, and Sankey visualizations are evaluated on their performance on different tasks, understandability, and user
S. van der Linden, M. C. Willemsen, M. D. Brunings, A. Vilanova, S. van den Elzen   +4 more
wiley   +1 more source

Disease progression in cardiac morphology and function in heart failure : ATTR cardiac amyloidosis versus hypertensive left ventricular hypertrophy

, 2022
BACKGROUND: Transthyretin cardiac amyloidosis (ATTR-CA) is today more frequently recognized but the rate of progression of cardiac dysfunction is not well established.
Henein, Michael Y., Pilebro, B., Henein, M. Y., Pilebro, Björn,, Lindqvist, Per,, Lindqvist, Per, Henein, Michael Y.,, Pilebro, Björn, Per Lindqvist, B. Pilebro, M. Y. Henein   +10 more
core   +1 more source

Transthyretin cardiac amyloidosis in aortic stenosis: Prevalence, diagnostic challenges, and clinical implications

Hellenic Journal of Cardiology, 2020
Transthyretin cardiac amyloidosis (ATTR-CA) is a challenging and underdiagnosed cause of heart failure. Advances in cardiac imaging have enabled noninvasive diagnosis of ATTR-CA, causing the recent upsurge in disease awareness and detection.
Giedre Balciunaite, Arnas Rimkus, Edvardas Zurauskas, Tomas Zaremba, Darius Palionis, Nomeda Valeviciene, Audrius Aidietis, Pranas Serpytis, Kestutis Rucinskas, Peter Sogaard, Sigita Glaveckaite, Aleksejus Zorinas, Vilius Janusauskas   +12 more
doaj   +1 more source