Results 91 to 100 of about 32,506 (196)

Eprodisate for the treatment of renal disease in AA amyloidosis [PDF]

, 2007
Background: Amyloid A (AA) amyloidosis is a complication of chronic inflammatory conditions that develops when proteolytic fragments of serum amyloid A protein (SAA) are deposited in tissues as amyloid fibrils.
Dember, L.M., Hazenberg, B.P.C., Garceau, D., Puéchal, X., Livneh, A., Lesnyak, O., Skinner, Martha, Lesnyak, Olga, Livneh, Avi, Butrimiene, I., Merlini, G., Hauck, Wendy, Obici, L., Dember, Laura M., Gorevic, Peter D., Skinner, M., Butrimiene, Irena, Hawkins, Philip N., Balshaw, Robert, Hazenberg, Bouke P. C.; id_orcid, Lachmann, Helen J., Obici, Laura, Gorevic, P.D., Puechal, Xavier, Hazenberg, Bouke P. C., Hawkins, P.N., Garceau, Denis, Balshaw, R., Lachmann, H.J., Merlini, Giampaolo, Hauck, W.   +30 more
core  

ATTR-CM in Patients With Clinically Significant Plasma Cell Dyscrasias

JACC: Case Reports
Background: Suspicion and diagnosis of transthyretin cardiac amyloidosis (ATTR-CM) in patients with clinically significant plasma cell disorders is challenging.
Bhavya Ancha, MD, Emily Brown, MGC, CGC, Mark Ranek, PhD, Nicole Lollo, CRNP, Carol Ann Huff, MD, Syed Abbas Ali, MBBS, Christian B. Gocke, MD, PhD, Phillip Imus, MD, Claire Brookmeyer, MD, Charles Steenbergen, Jr., MD, PhD, Michael Polydefkis, MD, Joban Vaishnav, MD   +11 more
doaj   +1 more source

Amyloid fibril polymorphism in the heart and liver of a patient with polyneuropathic ATTRv-V122Δ amyloidosis

Communications Biology
ATTR amyloidosis is a phenotypically heterogeneous disease characterized by the pathological deposition of transthyretin in the form of amyloid fibrils into various organs.
Yasmin Ahmed, Binh An Nguyen, Candace Kelly, Shumaila Afrin, Virender Singh, Bret M. Evers, John M. Shelton, Christian Lopez Escobar, Preeti Singh, Rose Pedretti, Lanie Wang, Parker Bassett, Maria del Carmen Fernandez-Ramirez, Maja Pekala, Andrew Lemoff, Barbara Kluve-Beckerman, Lorena Saelices   +16 more
doaj   +1 more source

Detection of ATTR aggregates in the plasma of polyneuropathic patients with ATTR-V30M amyloidosis

Amyloid
Detection of ATTR aggregates in the plasma of polyneuropathic patients with ATTR-V30M ...
Pedretti, Rose, Wang, Lanie, Grodin, Justin L., Masri, Ahmad, Kelly, Jeffery, Saelices, Lorena   +5 more
openaire   +2 more sources

Heart transplantation in hereditary ATTR amyloidosis [PDF]

Orphanet Journal of Rare Diseases, 2015
Systemic amyloidosis related to mutation of TTR gene can be complicated with Familial Amyloid Cardiomyopathy (TTR-FAC), a severe and life threatening form of heart failure with preserved ejection fraction, with a poor prognosis. To date there is no proven effective specific treatment against TTR-FAC, and the usual treatments of chronic heart failure ...
openaire   +1 more source

Coexistence of Light Chain and Transthyretin Cardiac Amyloidosis

JACC: Case Reports
Although most patients with cardiac amyloidosis are diagnosed with either light chain (AL) or transthyretin (ATTR) disease, coexisting amyloid subtypes can occur.
Abhishek Gami, MD, John Woller, MD, Paul Scheel, MD, Syed Abbas Ali, MBBS, Carol Ann Huff, MD, Charles Steenbergen, Jr., MD, PhD, Marc Halushka, MD, PhD, Kavita Sharma, MD, Michael Polydefkis, MD, Joban Vaishnav, MD   +9 more
doaj   +1 more source

野生型转甲状腺素蛋白心脏淀粉样变性病例1例

Zhongguo shiyan zhenduanxue, 2023
转甲状腺素蛋白心脏淀粉样变(transthyretin cardiac amyloidosis, ATTR-CA)是除外免疫球蛋白轻链心脏淀粉样变(immunoglobulin light chain amyloidosis, AL-CA)最常见的心脏淀粉样变(cardiac amyloidosis, CA)[1]。ATTR-CA患者生活质量差、生存率低[2]。
翟书慧, 王丹, 赵绮旎, 刘龙
doaj  

Myocardial perfusion imaging-derived left ventricular strain: Regional abnormalities associated with transthyretin cardiac amyloidosis

American Heart Journal Plus
Background: Transthyretin (ATTR) cardiac amyloidosis is associated with an apical-sparing strain pattern on TTE. We hypothesize that strain indices derived from myocardial perfusion imaging (MPI) can identify this abnormality.
Steven Lewis, Jingwen Huang, Nidhi Patel, Russell Folks, James Galt, C. David Cooke, Ziduo Zheng, Rebecca Zhang, Ernest Garcia, Jonathon Nye, Marina Piccinelli, Valeria Moncayo, Kunal Bhatt, Adam Mitchell   +13 more
doaj   +1 more source

Cryo-EM structure of a transthyretin-derived amyloid fibril from a patient with hereditary ATTR amyloidosis

, 2019
ATTR amyloidosis is one of the worldwide most abundant forms of systemic amyloidosis. The disease is caused by the misfolding of transthyretin protein and the formation of amyloid deposits at different sites within the body.
Wiese, Sebastian, Engler, Jonas, Zacharias, Martin, Schmidt, Matthias, Fändrich, Marcus, Agarwal, Shubhangi, Fritz, Günter, Westermark, Per, Adak, Volkan   +8 more
core   +1 more source

Cardiac amyloidosis in a Swiss autopsy cohort – distribution and clinical relevance

Swiss Medical Weekly
AIMS: Cardiac amyloidosis (CA) characterised by myocardial amyloid accumulation is likely underdiagnosed. The distribution and extent of myocardial amyloid deposits remain unclear.
Albert Baschong, Sara Ersözlü, Frank Ruschitzka, Andreas J. Flammer, Christoph A. Meier, Zsuzsanna Varga, Holger Moch, Umberto Maccio   +7 more
doaj   +1 more source