Results 111 to 120 of about 144,099 (322)

Attractor – a new turning point in drug discovery

open access: yesDrug Design, Development and Therapy, 2019
Xucan Hou, Meng Li, Congmin Jia, Xianbao Zhang, Yun WangDepartment of Traditional Chinese Medicine Information Fusion and Utilization, Beijing University of Chinese Medicine, Beijing, People’s Republic of ChinaCorrespondence: Yun WangDepartment of ...
Hou X, Li M, Jia C, Zhang X, Wang Y
doaj  

Attracting Diverse Students to Field Experiences Requires Adequate Pay, Flexibility, and Inclusion [PDF]

open access: hybrid, 2021
Alex J. Jensen   +13 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

SELF-EQUALITY AS A STRATEGY OF SPONTANEOUS TEXT GENERATION

open access: yesВестник Кемеровского государственного университета, 2017
The article deals with the results of the psycholinguistic experiment which prove the influence of the self-equality strategy in the process of spontaneous reaction text generation as a reaction on the stimulus “human life”.
G. G. Moskaltchuk
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Wild pseudohyperbolic attractor in a four-dimensional Lorenz system [PDF]

open access: green, 2021
Sergey S. Gonchenko   +2 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Attractors in black

open access: yesFortschritte der Physik, 2008
AbstractWe review recent results in the study of attractor horizon geometries (with non‐vanishing Bekenstein‐Hawking entropy) of dyonic extremal d = 4 black holes in supergravity. We focus on 𝒩 = 2, d = 4 ungauged supergravity coupled to a number nVof Abelian vector multiplets, outlining the fundamentals of the special Kähler geometry of the vector ...
Belluci, Stefano   +2 more
openaire   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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