Results 101 to 110 of about 32,819 (308)

Attractor classes and master graphs.

, 2022
A sampling of attractor classes from the full classification for n = 5 oriented graphs with no sinks. Each attractor emerges from multiple graphs which, once properly aligned, fit neatly into families that can be summarized by “master graphs” with ...
Samantha Moore (7147367), Carina Curto (269950), Caitlyn Parmelee (12197572), Katherine Morrison (3476588)   +3 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Disappearance of cancer attractor.

, 2018
(A) The landscape with the cancer attractor (a = 1.5, b = 0.05). (B) For a = 1.5, the cancer attractor disappears when the inhibition rate b is increased to 1.2.
Xiaomeng Zhang (182897), Ket Hing Chong (5091098), Jie Zheng (31208)   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Attractor

, 2017
The Theatre and Dance Platform holds a digital copy (PDF) of the archived ticket in the Lucy Guerin Inc collection.Ticket for Lucy Guerin and Gideon Obarzanek's Attractor at CAP UCLA, Royce Hall, Los Angeles, 2 November ...
UCLA Royce Hall
core   +2 more sources

Photoplethysmogram beat detection using Symmetric Projection Attractor Reconstruction

Frontiers in Physiology
Many methods have been proposed to detect beats in photoplethysmogram (PPG) signals. We present a novel method which uses the Symmetric Projection Attractor Reconstruction (SPAR) method to generate an attractor in a two dimensional phase space from the ...
Callum Pettit, Peter H. Charlton, Philip J. Aston   +2 more
doaj   +1 more source

Visualizing the transition to chaos in the Lorenz system

, 2006
The Lorenz system still fascinates many people because of the simplicity of the equations that generate such complicated dynamics on the famous butterfly attractor.
Osinga, HM, Doedel, EJ, Doedel, E.J., Krauskopf, B   +3 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

On the underlying assumptions of threshold Boolean networks as a model for genetic regulatory network behavior

Frontiers in Genetics, 2013
Boolean networks (BoN) are relatively simple and interpretable models of gene regulatorynetworks. Specifying these models with fewer parameters while retaining their ability to describe complex regulatory relationships is an ongoing methodological ...
Van eTran, Matthew Nicholson McCall, Helene eMcMurray, Anthony eAlmudevar   +3 more
doaj   +1 more source

Two-parameter locus of boundary crisis: mind the gaps!

, 2010
Boundary crisis is a mechanism for destroying a chaotic attractor when one parameter is varied. In a two-parameter setting the locus of boundary crisis is associated with curves of homo- or heteroclinic tangency bifurcations of saddle periodic orbits. It
Osinga, Hinke M, Rankin, J
core