Results 111 to 120 of about 107,710 (292)

Photoplethysmogram beat detection using Symmetric Projection Attractor Reconstruction

Frontiers in Physiology
Many methods have been proposed to detect beats in photoplethysmogram (PPG) signals. We present a novel method which uses the Symmetric Projection Attractor Reconstruction (SPAR) method to generate an attractor in a two dimensional phase space from the ...
Callum Pettit, Peter H. Charlton, Philip J. Aston   +2 more
doaj   +1 more source

On the underlying assumptions of threshold Boolean networks as a model for genetic regulatory network behavior

Frontiers in Genetics, 2013
Boolean networks (BoN) are relatively simple and interpretable models of gene regulatorynetworks. Specifying these models with fewer parameters while retaining their ability to describe complex regulatory relationships is an ongoing methodological ...
Van eTran, Matthew Nicholson McCall, Helene eMcMurray, Anthony eAlmudevar   +3 more
doaj   +1 more source

Cosmological Scaling Solutions of Multiple Tachyon Fields with Inverse Square Potentials

, 2004
We investigate cosmological dynamics of multiple tachyon fields with inverse square potentials. A phase-space analysis of the spatially flat FRW models shows that there exists power-law cosmological scaling solutions.
Aguirregabiria J M Lazkoz R, Bazeia D, Bento M C, Calcagni G, Guo Z K, Guo Z K, Heard I P C, Jones N T, Jones N T, Kluson J, Kofman L, Liddle A R, Liddle A R, Majumdar M Davis A C, Paul B C Sami M, Piao Y S, Sen A, Sen A, Yuan-Zhong Zhang, Zong-Kuan Guo   +19 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Distance in Visual Memory Phase Space Predicts Skill Acquisition Time: Evidence from Simulations of a Deep Neural Network

Mathematics
It is proposed that the process of learning may be represented as a trajectory within the phase space of long-term memory. The research uses an artificial neural network design to explore, in theory, if starting from different points within the phase ...
Philippe Chassy
doaj   +1 more source

SELF-EQUALITY AS A STRATEGY OF SPONTANEOUS TEXT GENERATION

Вестник Кемеровского государственного университета, 2017
The article deals with the results of the psycholinguistic experiment which prove the influence of the self-equality strategy in the process of spontaneous reaction text generation as a reaction on the stimulus “human life”.
G. G. Moskaltchuk
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Attractors in black

Fortschritte der Physik, 2008
AbstractWe review recent results in the study of attractor horizon geometries (with non‐vanishing Bekenstein‐Hawking entropy) of dyonic extremal d = 4 black holes in supergravity. We focus on 𝒩 = 2, d = 4 ungauged supergravity coupled to a number nVof Abelian vector multiplets, outlining the fundamentals of the special Kähler geometry of the vector ...
Belluci, Stefano, Ferrara, Sergio, Marrani, Alessio   +2 more
openaire   +3 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source