Results 91 to 100 of about 32,819 (308)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
THE ATTRACTOR AND THE QUANTUM STATES [PDF]
International Journal of Quantum Information, 2009 The dissipative dynamics anticipated in the proof of 't Hooft's existence theorem — "For any quantum system there exists at least one deterministic model that reproduces all its dynamics after prequantization" — is constructed here explicitly. We propose a generalization of Liouville's classical phase space equation, incorporating dissipation and ...
openaire +2 more sources
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
CoRR, 2017 Let $S$ be a string of length $n$. In this paper we introduce the notion of \emph{string attractor}: a subset of the string's positions $[1,n]$ such that every distinct substring of $S$ has an occurrence crossing one of the attractor's elements. We first show that the minimum attractor's size yields upper-bounds to the string's repetitiveness as ...
openaire +2 more sources
Attractor Bifurcation for Extended Fisher-Kolmogorov Equation [PDF]
, 2013 We consider the asymptotic stability and attractor bifurcation of the extended Fisher-Kolmogorov equation on the one-dimensional domain with Dirichlet or periodic boundary conditions.
Honglian You, Rong Yuan, Ziheng Zhang
core +1 more source
Unifying attractor and non-attractor models of inflation under a single soft theorem
, 2023 We study the generation of local non-Gaussianity in models of canonical single field inflation when their backgrounds are either attractor or non-attractor.
Palma, Gonzalo A. +2 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Attractor landscapes visualisation
, 2022 Figures depicting the concept of attractor landscapes.
matti heino (4788948)
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Oncogenesis- kaleidoscopic and multi-level reality
Journal of Mind and Medical Sciences, 2019 Oncogenesis is an extremely complex phenomenon. The mechanisms by which cancer is induced is only partially known. Consequently, therapeutic targets may be uncertain and results are often unsatisfactory.
Firmilian Calotă +3 more
doaj +1 more source