Results 91 to 100 of about 19,741 (278)

A Reference Model for Authentication and Authorisation Infrastructures Respecting Privacy and Flexibility in b2c eCommerce [PDF]

open access: yes, 2006
Authentication and Authorisation Infrastructures (AAIs) are gaining momentum throughout the Internet. Solutions have been proposed for various scenarios among them academia, GRID computing, company networks, and above all eCommerce applications. Products
Nowey, Thomas   +5 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Probability timed automata for investigating communication processes

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2015
Exploitation characteristics behaves as a decreasing valors factor (DVF) which can be connected with degradation processes. It is a structure that consists of independent attributes which represent situations generally connected with a given exploitation
Piech Henryk, Grodzki Grzegorz
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Um middleware para compartilhamento de documentos sigilosos em nuvens computacionais [PDF]

open access: yes, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Ciência da Computação, Florianópolis, 2014Diversas empresas tem investido no uso da tecnologia da computação em nuvem para o armazenamento ...
Souza, Rick Lopes de
core  

A distributed authentication and authorization scheme for in-network big data sharing

open access: yesDigital Communications and Networks, 2017
Big data has a strong demand for a network infrastructure with the capability to support data sharing and retrieval efficiently. Information-centric networking (ICN) is an emerging approach to satisfy this demand, where big data is cached ubiquitously in
Ruidong Li   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

A New Era of Cryptography: Quantum Cryptography [PDF]

open access: yes, 2017
Security is the first priority in today digital world for secure communication between sender and receiver. Various Cryptography techniques are developed time to time for secure communication.
Bhandari, Sandeepak
core  

A Novel Efficient Pairing-Free CP-ABE Based on Elliptic Curve Cryptography for IoT

open access: yesIEEE Access, 2018
Ciphertext-policy attribute-based encryption (CP-ABE) is a promising cryptographic technique that integrates data encryption with access control for ensuring data security in IoT systems.
Sheng Ding, Chen Li, Hui Li
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

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