Results 31 to 40 of about 6,703,622 (155)

IgA mediated anti-glomerular basement membrane disease with associated circulating anti-neutrophil cytoplasm antibodies [PDF]

Journal of Nephropathology
Anti-glomerular basement membrane (anti-GBM) disease is an aggressive small vessel vasculitis usually mediated by IgG autoantibodies. We describe the case of a 73-year-old male with rapidly progressive renal failure that was diagnosed with IgA mediated ...
Patricia Alves, Mário Góis, Tiago Pereira, Dulce Carvalho, Fernando Nolasco   +4 more
doaj   +1 more source

Seronegative Atypical Anti-Glomerular Basement Membrane Glomerulonephritis Associated With Thrombotic Microangiopathy: Case Report and Literature Analysis

Journal of Investigative Medicine High Impact Case Reports, 2023
Anti-glomerular basement membrane (GBM) antibody nephritis is defined by linear immunofluorescence staining of GBM by immunoglobulin G (IgG), typically associated with GBM rupture, fibrinoid necrosis, and crescent formation.
Sasmit Roy MD, Jean Hou MD, Prabal Chourasia MD, Anish Yalamanchili BSc, Debargha Basuli MD, Praveen Kumar Errabelli MD, Samanvitha Sai Yarram BSc, Raul Ayala MD, Sreedhar Adapa MD   +8 more
doaj   +1 more source

Clinical-Pathological Features and Outcome of Atypical Anti-glomerular Basement Membrane Disease in a Large Single Cohort

Frontiers in Immunology, 2020
Background: Atypical cases of anti-glomerular basement membrane (GBM) disease had absent circulating antibodies but linear IgG deposits along GBM in the kidneys.
Cong-rong Shen, Cong-rong Shen, Cong-rong Shen, Cong-rong Shen, Cong-rong Shen, Xiao-yu Jia, Xiao-yu Jia, Xiao-yu Jia, Xiao-yu Jia, Xiao-yu Jia, Zhao Cui, Zhao Cui, Zhao Cui, Zhao Cui, Zhao Cui, Xiao-juan Yu, Xiao-juan Yu, Xiao-juan Yu, Xiao-juan Yu, Xiao-juan Yu, Ming-hui Zhao, Ming-hui Zhao, Ming-hui Zhao, Ming-hui Zhao, Ming-hui Zhao, Ming-hui Zhao   +25 more
doaj   +1 more source

Anti-Glomerular Basement Membrane Disease [PDF]

, 2018
Anti–glomerular basement membrane (GBM) disease often presents with rapidly progressive glomerulonephritis with or without lung hemorrhage. It is rare to present with lung hemorrhage alone.
Kavita Gulati, Gulati, Kavita, McAdoo, Stephen P, Stephen P. McAdoo   +3 more
core   +1 more source

Heavy chain deposition disease presenting with raised anti-GBM antibody levels; a case report

BMC Nephrology, 2020
Background Monoclonal immunoglobulin deposition disease (MIDD) is a rare condition accounting for
Michael Turner, Anna Crawford, Claire Winterbottom, Oliver Flossmann, Bassam Alchi, Maria Soares, Umanath Bhandary   +6 more
doaj   +1 more source

Co-injection of anti-HS antibodies during anti-GBM-induced glomerulonephritis induces a transient increase in albuminuria and decline in renal function.

, 2021
Blood urea nitrogen (BUN) levels after (A) 2 hours, (B) 1 day and (C) 4 days. Urinary albumin concentration after 2 hours (D) and urinary albumin:creatinine ratios after (E) 1 day and (F) 4 days anti-GBM-induced glomerulonephritis.
Toin H. van Kuppevelt (10013111), Nathalie J. H. G. Passmann (11873757), Markus A. Loeven (3368984), Jasper J. van Gemst (3368987), Bart Smeets (170582), Johan van der Vlag (45996), Jo H. Berden (11873763), Ton J. Rabelink (8695392), Angelique L. W. M. M. Rops (11873760)   +8 more
core   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

A case of bizarre posttransplant anti-glomerular basement membrane disease

Central European Journal of Immunology, 2019
The non-collagenous (NC1) domain of 3 and 5 chains of type IV collagen are eminent targets of abnormal immune response in anti-glomerular basement membrane (anti-GBM) disease, which can be diagnosed by the presence of strong linear IgG staining along ...
Anna Olewicz-Gawlik, Jan Żeromski, Monika Świerczewska, Ilona Idasiak-Piechocka, Magdalena Pawlik, Dorota Sikorska, Husam Samara, Andrzej Oko, Jan Sikora, Grzegorz Dworacki   +9 more
doaj   +1 more source

Nephrotic syndrome due to minimal-change disease superimposed on anti-glomerular basement membrane antibody positive glomerulonephritis; a case report

BMC Nephrology, 2020
Background The prognosis for renal function in anti-GBM glomerulonephritis (anti-GBM GN) is extremely poor, and when renal impairment progresses severely, it is difficult to expect improvement. In addition, it is also known that once the disease activity
Yuko Shibata, Kazuhito Fukuoka, Riyo Yokota, Heryon Lee, Hikaru Sayo, Noriko Ikegaya, Kiyotaka Mori, Jin Yamamoto, Aya Isomura, Kiyotaka Nagahama, Hiroaki Shimoyamada, Takahisa Kawakami, Yoshinori Komagata, Shinya Kaname   +13 more
doaj   +1 more source

Laboratory solution to diagnose and monitor atypical IgG4-mediated anti-GBM disease

Clinical Chemistry and Laboratory Medicine (CCLM)
Abstract Objectives Diagnosing atypical IgG4-mediated anti-glomerular basement membrane (anti-GBM) disease is challenging because conventional serological assays poorly detect IgG4 antibodies. Here we study which commercial assays are affected and we describe proof-of-concept of improved IgG4 ...
Joannes F M, Jacobs, Annechien J A, Lambeck, Rosa G M, Lammerts, Anne-Els, van de Logt, Jan-Stephan, Sanders, Mark, Lenssen, Mark, Eijgelsheim, Ingeborg, Bajema, Eric J, Steenbergen, Wibe, Hoefsloot, Wilbert A G, van der Meijden, Renate G, van der Molen   +11 more
openaire   +3 more sources