Results 51 to 60 of about 6,703,622 (155)

Living Microbial Drugs

Chemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik, Nazlıcan Tunç, Senem Şen, Urartu Özgür Şafak Şeker   +3 more
wiley   +1 more source

Atypical Anti-Glomerular Basement Membrane Nephritis After the First Dose of the Severe Acute Respiratory Syndrome Coronavirus 2 mRNA Vaccine [PDF]

023460361801082Atypical anti-glomerular basement membrane (GBM) nephritis is a slowly progressive characterized by linear deposition of immunoglobulin (Ig) G in the GBM without circulating anti-GBM antibodies or lung involvement.
ムネムラ, チシオ, Isomoto, Hajime, 40931, 40930, 宗村, 千潮, 100001163, 1082, 40933, イソモト, ハジメ, 40932, 高田, 知朗, 100001541, 2346, 90322304, Hoi, Shotaro, 100000438, Munemura, Chishio, タカタ, トモアキ, Takata, Tomoaki, 磯本, 一, 3618, Ogawa, Masaya   +21 more
core   +1 more source

Crescentic Glomerulonephritis with Anti-GBM and p-ANCA Antibodies [PDF]

, 2012
We are presenting a case of renal failure with anti-GBM and p-ANCA antibodies positive. Patients with dual antibodies are considered to be a vasculitis-variant of anti-GBM antibody nephritis. These patients may have atypical presentation and it may delay
Parag Vohra, Tariq Javed
core   +1 more source

Utility of serological markers in inflammatory bowel diseases: Gadget or magic? [PDF]

, 2007
The panel of serologic markers for inflammatory bowel diseases (IBD) is rapidly expanding. Although anti-Saccharomyces cerevisiae antibodies (ASCA) and atypical perinuclear antineutrophil cytoplasmic antibodies (P-ANCA) remain the most widely ...
Papp, Mária, Lakatos, Péter László, Norman, G. L., Altorjay, István   +3 more
core   +1 more source

Anti-glomerular basement membrane disease with concomitant myeloperoxidase antibodies in a pediatric patient: a case report of presentation, treatment and outcome a rare disease [PDF]

Childhood Kidney Diseases
Anti-glomerular basement membrane disease (anti-GBMD) is a rare small-vessel vasculitis presenting as rapidly progressive glomerulonephritis and/or diffuse alveolar hemorrhage. A third of patients with anti-GBMD have antineutrophil cytoplasmic antibodies
Yiressy Pina, Emily Frierson, John Hicks, Partha Chakraborty, Alvaro Orjuela, Amit Thakral   +5 more
doaj   +1 more source

Cancer Heterogeneity and Cancer Cell Plasticity: Molecular Mechanisms and Precision Therapy

MedComm, Volume 7, Issue 7, July 2026.
Tumor progression is driven by heterogeneity occurring across multiple biological scales. At the molecular level, tumor cells exhibit alterations across distinct omics layers, including genomic mutations, epigenomic reprogramming, transcriptional changes, and proteomic remodeling, collectively shaping tumor cell phenotypes and functional states.
Hanwen Hu, Zhixing Hao, Lili Li, Huiying Liu, Chenghui Yang, Zhen Wang   +5 more
wiley   +1 more source

Co-injection of anti-HS antibodies in anti-GBM-induced glomerulonephritis differentially affects glomerular PMN and macrophage influx.

, 2021
Glomerular PMN influx after (A) 2 hours, (B) 1 day and (C) 4 days, and glomerular macrophage influx after (D) 2 hours, (E) 1 day and (F) 4 days analyzed by immunofluorescence staining. Results are expressed as means ± s.e.m. from four mice in each group.
Toin H. van Kuppevelt (10013111), Nathalie J. H. G. Passmann (11873757), Markus A. Loeven (3368984), Jasper J. van Gemst (3368987), Bart Smeets (170582), Johan van der Vlag (45996), Jo H. Berden (11873763), Ton J. Rabelink (8695392), Angelique L. W. M. M. Rops (11873760)   +8 more
core   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, Volume 13, Issue 35, 24 June 2026.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Epidemiology, Impact, and Management Strategies of Anti-Glomerular Basement Membrane Disease

International Journal of Nephrology and Renovascular Disease, 2022
Muhammad Asim,1 Mohammed Akhtar2 1Division of Nephrology, Department of Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar; 2Department of Laboratory Medicine and Pathology, Hamad General Hospital, Hamad Medical Corporation, Doha ...
Asim M, Akhtar M
doaj  

Metal‐dependent regulated cell death: Molecular architecture and translational frontiers

iMeta, Volume 5, Issue 3, June 2026.
Intracellular metal dyshomeostasis orchestrates distinct regulated cell death programs, including iron‐driven ferroptosis, copper‐mediated cuproptosis, calcicoptosis, newly designated zincoptosis, mnoptosis, and coptosis. This review systematically delineates their molecular architectures—spanning from Sorafenib‐induced lipid peroxidation and ...
Haoliang Hu, Zhe Chen, Yaqi Li, Jiayi Peng, Jiangang Cao, Hong Zhou, Mengqi Wang, Yuejia Du, Hailin Wu, Huiqin Zhao, Shifang Huang, Dianmei Yu, Meiqing Liu, Olga V. Shevchenko, Natalia Yu. Matveeva, Yiyuan Yang, Kerui Huang, Deguan Lv, Junxia Min, Linxi Chen, Fudi Wang   +20 more
wiley   +1 more source