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Atypical bovine spongiform encephalopathy (BSE) has recently been identified in Europe, North America, and Japan. It is classified as H-type and L-type BSE according to the molecular mass of the disease-associated prion protein (PrPSc).
Okada Hiroyuki +9 more
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Bovine Spongiform Encephalopathy in the UK: An Update
Bovine Spongiform Encephalopathy, BSE, was first diagnosed in England in November 1986. It is a slow disease and the incubation period varies between two and five years, and so mainly affects cows.
Edmondson, Peter W.
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This report presents the results of surveillance on transmissible spongiform encephalopathies (TSE) in bovine animals, sheep, goats, cervids and other species, and genotyping in sheep, carried out in 2018 by 28 Member States (MS) according to legislation,
European Food Safety Authority (EFSA)
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Prevalence of the prion protein gene E211K variant in U.S. cattle
Background In 2006, an atypical U.S. case of bovine spongiform encephalopathy (BSE) was discovered in Alabama and later reported to be polymorphic for glutamate (E) and lysine (K) codons at position 211 in the bovine prion protein gene (Prnp) coding ...
Chase Chad C +16 more
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Below, by the following five topics, are some questions and answers related to this situation:Topics:1. Bovine spongiform encephalopathy (BSE)2. Other human and animal transmissible spongiform encephalopathies (TSEs)3. Creutzfeldt-Jakob disease (CJD) and
Detwiler, Linda A.
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After the detection of bovine spongiform encephalopathy (BSE), and a zoonotic transmissible spongiform encephalopathy (TSE) caused by the pathological prion protein (PrPSc) in two goats, the investigation of goat prions became of greater interest ...
Sonja Ernst +12 more
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The Molecular Pathology of Prion Diseases [PDF]
Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of invariably fatal neurodegenerative disorders. Uniquely, they may present as sporadic, inherited, or infectious forms, all of which involve conversion of the normal ...
Vassallo, Neville +2 more
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Epidemiology of bovine spongiform encephalopathy in Northern Ireland 1988 to 1995
Epidemiology of bovine spongiform encephalopathy in Northern Ireland 1988 to 1995.
Hueston, W. D., Denny, G. O.
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This report of EFSA presents the results of surveillance activities on transmissible spongiform encephalopathies (TSEs) in bovine animals, sheep and goats as well as genotyping data in sheep, carried out in 2015 in the EU and in three non‐Member States ...
European Food Safety Authority (EFSA) +6 more
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Atypical and classic bovine spongiform encephalopathy
This chapter describes the prion diseases of cattle, or bovine transmissible spongiform encephalopathies (BoTSEs). “Classic” bovine spongiform encephalopathy (C-BSE), the major prion protein disorder of Bovidae, was first described in 1986.
Casalone, Cristina +3 more
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