Brazilian Journal of Veterinary Pathology, 2013 The number of cases of Bovine Spongiform Encephalopathy (BSE) in the United Kingdom (UK) and Europe has decreased during the last years. The disease is designated as Classical BSE (C-BSE) once the prion protein involved is very constant and has genetic ...
Antonio C. Alessi
doaj +3 more sources
Detection of classical BSE prions in asymptomatic cows after inoculation with atypical/Nor98 scrapie [PDF]
Veterinary Research, 2023 The emergence of bovine spongiform encephalopathy (BSE) prions from atypical scrapie has been recently observed upon experimental transmission to rodent and swine models. This study aimed to assess whether the inoculation of atypical scrapie could induce
Marina Betancor +11 more
doaj +7 more sources
Classical BSE prions emerge from asymptomatic pigs challenged with atypical/Nor98 scrapie [PDF]
Scientific Reports, 2021 Pigs are susceptible to infection with the classical bovine spongiform encephalopathy (C-BSE) agent following experimental inoculation, and PrPSc accumulation was detected in porcine tissues after the inoculation of certain scrapie and chronic wasting ...
Belén Marín +12 more
doaj +10 more sources
Atypical BSE: Current Knowledge and Knowledge Gaps [PDF]
Food Safety (Tokyo, Japan), 2017 Atypical BSE is an invariably fatal neurologic disease of cattle caused by misfolded prion proteins with different conformations than those associated with classical BSE. Evidence suggests that these atypical BSE types are sporadic or genetic prion diseases of cattle and the relevance of these diseases, as far as natural transmissibility, is still ...
Stefanie Czub, Sándor Dudas
exaly +5 more sources
Estimation of prion infectivity in tissues of cattle infected with atypical BSE by real time-quaking induced conversion assay [PDF]
Journal of Veterinary Medical Science, 2019 Atypical bovine spongiform encephalopathy (BSE), first identified in 2004, poses a threat due to the potential to spread the disease to cattle and other animals, including humans. Here, we estimated prion titers in various tissues of cattle infected with atypical BSE using a real-time quaking-induced conversion assay that detects amyloid seeding ...
Ryuichiro Atarashi +2 more
exaly +5 more sources
Evaluation of rapid post-mortem test kits for bovine spongiform encephalopathy (BSE) screening in Japan: Their analytical sensitivity to atypical BSE prions [PDF]
Prion, 2017 A classical type of bovine spongiform encephalopathy (C-BSE), recognized in 1987, had a large impact on public health due to its zoonotic link to variant Creutzfeldt-Jakob disease by the human consumption of dietary products contaminated with the C-BSE prion.
Minoru Tobiume +2 more
exaly +5 more sources
Intra- and Interspecies Transmission of Atypical BSE - What Can We Learn from It? [PDF]
Food Saf (Tokyo), 2016 After the detection of the first cases of atypical bovine spongiform encephalopathy (BSE) more than ten years ago, the etiology, pathogenesis and agent distribution of these novel BSE forms in cattle were completely unknown.
Balkema-Buschmann A +5 more
europepmc +5 more sources
No H- and L-type cases in Belgium in cattle diagnosed with bovine spongiform encephalopathy (1999-2008) aging seven years and older [PDF]
BMC Veterinary Research, 2010 Background The bovine spongiform encephalopathy (BSE) epidemic presented homogeneity of the phenotype. This classical BSE (called C-type) was probably due to the contamination of the food chain by a single prion strain.
Van Muylem Patrick +9 more
doaj +2 more sources
Atypical BSE (BASE) transmitted from asymptomatic aging cattle to a primate. [PDF]
PLoS ONE, 2008 BACKGROUND: Human variant Creutzfeldt-Jakob Disease (vCJD) results from foodborne transmission of prions from slaughtered cattle with classical Bovine Spongiform Encephalopathy (cBSE).
Emmanuel E Comoy +15 more
doaj +4 more sources
Atypical variants of bovine spongiform encephalopathy: rare diseases with consequences for BSE surveillance and control [PDF]
Schweiz Arch Tierheilkd, 2016 Occurring for the first time in 1986 in the United Kingdom, bovine spongiform encephalopathy (BSE), the so-called “mad-cow disease”, has had unprecedented consequences in veterinary public health.
Serra, Fabienne Heirangi +2 more
core +6 more sources