Results 21 to 30 of about 8,784 (177)
Eculizumab in Atypical Hemolytic–Uremic Syndrome [PDF]
New England Journal of Medicine, 2013 To the Editor: With regard to the article by Legendre et al. (June 6 issue)(1): assessment of the 37 patients with atypical hemolytic-uremic syndrome is difficult, since the process of selection seems opaque, particularly for the 20 patients in trial 2.
Christophe M, Legendre +2 more
openaire +9 more sources
Atypical hemolytic uremic syndrome: a case report [PDF]
Journal of Medical Case Reports, 2020 Background Thrombotic microangiopathy is a pathological condition comprised of microvascular thrombosis involving any organ of the body leading to thrombocytopenia, Coombs-negative hemolytic anemia, and end-organ damage.
B. M. D. B. Basnayake +7 more
doaj +3 more sources
Atypical hemolytic-uremic syndrome in children
Инновационная медицина Кубани, 2022 Background: Atypical hemolytic-uremic syndrome (aHUS) is a rare progressive form of systemic thrombotic microangiopathy (TMA), which develops due to uncontrolled activation of the alternative pathway of the complement system and is characterized by a ...
A. V. Burlutskaya +3 more
doaj +3 more sources
Atypical hemolytic uremic syndrome
Pediatrics International, 1995 AbstractThe pathogenesis of atypical uremic syndrome (HUS), which is rarely encountered in childhood, is poorly understood and its mortality and morbidity rates are high. A wide variety of therapeutic approaches has been attempted and the literature contains numerous conflicting reports about the results of these approaches.
KAVUKÇU S. +3 more
core +6 more sources
Pediatric Atypical Hemolytic Uremic Syndrome Advances [PDF]
Cells, 2021 Atypical hemolytic uremic syndrome (aHUS) is a rare disorder characterized by dysregulation of the alternate pathway. The diagnosis of aHUS is one of exclusion, which complicates its early detection and corresponding intervention to mitigate its high ...
Rupesh Raina +9 more
doaj +3 more sources
An Atypical Cause Of Atypical Hemolytic Uremic Syndrome
Marshall Journal of Medicine, 2016 Atypical hemolytic syndrome is an extremely rare, life threatening, progressive disease. Approximately one to two cases per million are seen annually in the US (3,4).
Abhinav Sharma +3 more
doaj +2 more sources
Successful use of eculizumab to treat atypical hemolytic uremic syndrome in patients with inflammatory bowel disease [PDF]
Thrombosis Journal, 2019 Background Atypical hemolytic uremic syndrome is a rare group of disorders that have in common underlying complement amplifying conditions. These conditions can accelerate complement activation that results in a positive feedback cycle.
Ramy M. Hanna +8 more
doaj +2 more sources
Atypical hemolytic-uremic syndrome, manifesting without thrombocytopenia (clinical case)
Известия высших учебных заведений. Поволжский регион: Медицинские наукиBackground. Atypical hemolytic uremic syndrome is an ultra-rare (orphan) disease from the group of thrombotic microangiopathies of progressive course, which is caused by uncontrolled activation of the alternative complement pathway of hereditary or ...
A.A. Dyachkova +3 more
doaj +2 more sources
Eculizumab experience in an adult patient with atypical hemolytic uremic syndrome
Saudi Journal of Kidney Diseases and Transplantation, 2017 Atypical hemolytic-uremic syndrome is a disease characterized by nonimmune hemolytic anemia, thrombocytopenia, and renal failure. In this study, we present a case of a patient with atypical hemolytic-uremic syndrome treated successfully with eculizumab ...
Funda Sari +6 more
doaj +2 more sources
Skin Involvement in Atypical Hemolytic Uremic Syndrome
American Journal of Kidney Diseases, 2014 Skin involvement in atypical hemolytic uremic syndrome (aHUS) is very uncommon and therefore often unrecognized as a specific symptom of aHUS. We describe 3 cases of patients with aHUS who developed skin lesions that completely recovered when disease-specific treatment was established.
ARDISSINO, GIAN LUIGI +6 more
openaire +4 more sources