Results 21 to 30 of about 6,998 (166)

Hemolytic uremic syndrome related to Shiga-like toxin-producing Escherichia coli with encephalitis hiding a human herpesvirus-6 infection: a case report

Journal of Medical Case Reports, 2021
Background Cardiac and neurological involvement in hemolytic uremic syndrome are life-threatening complications. The most frequent complications of cardiac involvement in hemolytic uremic syndrome are myocarditis and cardiac dysfunction due to fluid ...
Sophie Mounier, Arthur Gavotto, Julie Tenenbaum, Pierre Meyer, Marc Fila, Julien Baleine   +5 more
doaj   +1 more source

Genetics of Atypical Hemolytic Uremic Syndrome (aHUS) [PDF]

Seminars in Thrombosis and Hemostasis, 2014
Hemolytic uremic syndrome (HUS) is a rare, life-threatening disease characterized by thrombocytopenia, microangiopathic hemolytic anemia, and acute renal failure. The atypical form of HUS (aHUS), representing 5 to 10% of cases, lacks the association with infection by Shiga toxin producing Escherichia coli strains that characterizes the commonest ...
Rodriguez de Cordoba, Santiago, Subias Hidalgo, Marta, Pinto, Sheila, Tortajada Alonso, Agustín   +3 more
openaire   +4 more sources

Atypical hemolytic uremic syndrome

Journal of Allergy and Clinical Immunology
Hemolytic uremic syndromes are a heterogeneous group of conditions with differing underlying pathophysiology. These all result in pathologic features of thrombotic microangiopathy (TMA), which cause endothelial damage and organ injury. TMAs manifest with a microangiopathic hemolytic anaemia, thrombocytopenia, and commonly acute kidney injury.
Patrick R. Walsh, David Kavanagh
  +5 more sources

Phenotypic manifestation of homozygous partial deletion of the chromosome 1 segment spanning CFHR3 region

Медицинская иммунология, 2020
This article presents two clinical cases of patients with a homozygous deletion of segment of chromosome 1, which covers regions of genes associated with complement factor H, in particular CFHR3.
I. A. Tuzankina, M. A. Bolkov, N. S. Zhuravleva, Yu. O. Vaseneva, Kh. Shinvari, O. V. Schipacheva   +5 more
doaj   +1 more source

Hemolytic uremic syndrome (HUS) – case report

Journal of Education, Health and Sport, 2020
Introduction Hemolytic uremic syndrome (HUS) is characterized by hemolytic anemia, thrombocytopenia and acute renal failure. In 90% of children, HUS most often develops after an intestinal infection caused by verotoxin-producing E. coli. The remaining 10%
Aleksandra Borkowska, Anna Sobstyl, Aleksandra Chałupnik, Zuzanna Chilimoniuk, Maciej Dobosz, Szymon Marosz   +5 more
doaj   +1 more source

Small-molecule factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome

Haematologica, 2017
Paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome are diseases of excess activation of the alternative pathway of complement that are treated with eculizumab, a humanized monoclonal antibody against the terminal complement ...
Xuan Yuan, Eleni Gavriilaki, Jane A. Thanassi, Guangwei Yang, Andrea C. Baines, Steven D. Podos, Yongqing Huang, Mingjun Huang, Robert A. Brodsky   +8 more
doaj   +1 more source

Atypical hemolytic-uremic syndrome in children

Инновационная медицина Кубани, 2022
Background: Atypical hemolytic-uremic syndrome (aHUS) is a rare progressive form of systemic thrombotic microangiopathy (TMA), which develops due to uncontrolled activation of the alternative pathway of the complement system and is characterized by a ...
A. V. Burlutskaya, A. V. Statova, D. V. Ustyuzhaninа, Yu. V. Pisotskaya   +3 more
doaj   +1 more source

Pregnancy in Women with Atypical Hemolytic Uremic Syndrome [PDF]

Nephron, 2021
<b><i>Background:</i></b> Pregnancy outcomes in patients with atypical hemolytic uremic syndrome (aHUS) are not well-documented. Here, we present characteristics of and outcomes for patients with aHUS who became pregnant while enrolled in the Global aHUS Registry.
Eric, Rondeau, Gianluigi, Ardissino, Marie-Pierre, Caby-Tosi, Imad, Al-Dakkak, Fadi, Fakhouri, Benjamin, Miller, Marie, Scully   +6 more
openaire   +2 more sources

Case Series of 3 Patients Diagnosed With Atypical Hemolytic Uremic Syndrome Successfully Treated With Steroids, Plasmapheresis, and Rituximab

Canadian Journal of Kidney Health and Disease, 2017
Rationale: Atypical hemolytic uremic syndrome, which has a high probability of chronic kidney disease, morbidity, and mortality, needs to be promptly recognized when patients present with microangiopathic hemolysis.
Jeffery M. Patterson, Lauren Bolster, Loree Larratt   +2 more
doaj   +1 more source

Successful use of eculizumab to treat atypical hemolytic uremic syndrome in patients with inflammatory bowel disease

Thrombosis Journal, 2019
Background Atypical hemolytic uremic syndrome is a rare group of disorders that have in common underlying complement amplifying conditions. These conditions can accelerate complement activation that results in a positive feedback cycle.
Ramy M. Hanna, Noah Merin, Richard M. Burwick, Lama Abdelnour, Umut Selamet, Beshoy Yanny, Patrick Bui, Mary Fouad, Ira Kurtz   +8 more
doaj   +1 more source