Results 41 to 50 of about 8,784 (177)

Transplantation in Atypical Hemolytic Uremic Syndrome [PDF]

Seminars in Thrombosis and Hemostasis, 2010
Atypical hemolytic uremic syndrome (aHUS) is a disease characterized by overactivation of complement. Recurrence following renal transplantation is determined by a genetic predisposition. Genetic screening of all individuals with aHUS should be performed prior to listing for transplantation. Individuals with isolated mutations in MCP have a low risk of
Kavanagh D, Richards A, Goodship T, Jalanko H   +3 more
openaire   +3 more sources

Influenza B-Associated Atypical Hemolytic Uremic Syndrome [PDF]

Revista Portuguesa de Nefrologia e Hipertensão, 2022
Hemolytic uremic syndrome (HUS) triggered by influenza virus (iHUS) is rare. Influenza A infections have been described to trigger atypical HUS (aHUS) in individuals with an underlying genetic complement dysregulation. To date there are only few reports
Lia Mano, Telma Francisco, Joana Gaspar, Gabriela Pereira, Raquel Santos, Margarida Abranches   +5 more
doaj   +1 more source

The genetics of atypical hemolytic uremic syndrome [PDF]

Medizinische Genetik, 2018
Abstract Atypical hemolytic uremic syndrome (aHUS) is a disorder characterized by thrombocytopenia and microangiopathic hemolytic anemia due to endothelial injury. aHUS is felt to be caused by defective complement regulation due to underlying genetic mutations in complement regulators or activators, most often of the alternative pathway.
Feitz, W.JC., van de Kar, N.CA.J., Orth-Höller, D., van den Heuvel, L.PJ.W., Licht, C.   +4 more
openaire   +3 more sources

Atypical Hemolytic Uremic Syndrome

Pediatric Clinics of North America, 2018
Atypical hemolytic uremic syndrome is a rare life-threatening disease of unregulated complement activation. Untreated, the prognosis is generally poor; more than one-half of patients die or develop end-stage renal disease within 1 year. Atypical hemolytic uremic syndrome is characterized by thrombotic microangiopathy with evidence of hemolysis ...
Bradley P. Dixon, Ralph A. Gruppo
  +7 more sources

Pregnancy-Induced Atypical Hemolytic Uremic Syndrome. [PDF]

Cureus
Atypical hemolytic uremic syndrome (aHUS) is a rare form of thrombotic microangiopathy that causes anemia, thrombocytopenia, and acute renal failure. In aHUS, a triggering event can lead to dysregulation of the complement immune system, leading to a cascade of events resulting in clot formation, capillary thrombosis, and renal dysfunction.
Den Boef A, Parekh S, O'Brien MC, Liu S, Jacob R.   +4 more
europepmc   +3 more sources

Hemolytic uremic syndrome related to Shiga-like toxin-producing Escherichia coli with encephalitis hiding a human herpesvirus-6 infection: a case report

Journal of Medical Case Reports, 2021
Background Cardiac and neurological involvement in hemolytic uremic syndrome are life-threatening complications. The most frequent complications of cardiac involvement in hemolytic uremic syndrome are myocarditis and cardiac dysfunction due to fluid ...
Sophie Mounier, Arthur Gavotto, Julie Tenenbaum, Pierre Meyer, Marc Fila, Julien Baleine   +5 more
doaj   +1 more source

Atypical hemolytic uremic syndrome

Journal of Allergy and Clinical Immunology
Hemolytic uremic syndromes are a heterogeneous group of conditions with differing underlying pathophysiology. These all result in pathologic features of thrombotic microangiopathy (TMA), which cause endothelial damage and organ injury. TMAs manifest with a microangiopathic hemolytic anaemia, thrombocytopenia, and commonly acute kidney injury.
Patrick R. Walsh, David Kavanagh
  +5 more sources

Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome

, 2021
Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement ...
Alfonso Jose Gonzalez-Vergara (10467822), John Fredy Nieto-Rios (5788220), Diana Carolina Bello-Marquez (4750176), Lina Maria Serna-Higuita (5788226)   +3 more
core   +1 more source

Delayed and sequencial hemolytic uremic syndrome as a complication of Gemcitabine therapy

, 2022
Gemcitabine is a widely used drug in the treatment of diverse malignancies and its use has been approved by the US Food and Drug Administration. This drug has been associated with a rare adverse event, the Hemolytic Uremic Syndrome (HUS), characterized ...
Paulo Marcelo Gehm Hoff, Renata Colombo Bonadio, Paulo Henrique Amor-Divino, Rafaela Lopes da Silva Naves, Thaís Sampaio Corrêa de Almeida   +4 more
core   +1 more source

Phenotypic manifestation of homozygous partial deletion of the chromosome 1 segment spanning CFHR3 region

Медицинская иммунология, 2020
This article presents two clinical cases of patients with a homozygous deletion of segment of chromosome 1, which covers regions of genes associated with complement factor H, in particular CFHR3.
I. A. Tuzankina, M. A. Bolkov, N. S. Zhuravleva, Yu. O. Vaseneva, Kh. Shinvari, O. V. Schipacheva   +5 more
doaj   +1 more source