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WCN24-1000 OUTCOMES OF ATYPICAL HEMOLYTIC UREMIC SYNDROME

Kidney International Reports
Narayan Prasad, Vamsi Veeranki, Jeyakumar Meyyappan, Ravi Shankar Kushwaha, Manas Ranjan Patel, Dharmendra Bhadauria, Anupama Kaul, Monika Yachha   +7 more
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Proteinuria and Exposure to Eculizumab in Atypical Hemolytic Uremic Syndrome

American Society of Nephrology. Clinical Journal, 2023
Visual Abstract Background Eculizumab is a monoclonal antibody for the treatment of atypical hemolytic uremic syndrome (aHUS). Kidney damage, a common condition in patients with aHUS, may result in proteinuria.
Mendy Ter Avest, Hilbert Steenbreker, R. Bouwmeester, Caroline Duineveld, K. Wijnsma, L. P. van den Heuvel, S. Langemeijer, J. Wetzels, N. C. van de Kar, R. ter Heine   +9 more
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Atypical hemolytic uremic syndrome

Pediatrics International, 1995
AbstractThe pathogenesis of atypical uremic syndrome (HUS), which is rarely encountered in childhood, is poorly understood and its mortality and morbidity rates are high. A wide variety of therapeutic approaches has been attempted and the literature contains numerous conflicting reports about the results of these approaches.
İRKEN G., KAVUKÇU S., OLGUN N., GÜÇLÜ A.   +3 more
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Plasmatherapy in Atypical Hemolytic Uremic Syndrome [PDF]

Seminars in Thrombosis and Hemostasis, 2010
Plasmatherapy has become empirically first-line treatment in atypical hemolytic uremic syndrome (aHUS), although no prospective controlled trials have been conducted. Patients with mutations that induce complete or partial factor H (FH) quantitative deficiency may be controlled by plasma infusions (PI), but plasma exchanges appear more efficient than ...
Theresa Kwon, Chantal Loirat, Anne-Laure Sellier-Leclerc, Arnaud Garnier   +3 more
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Atypical hemolytic uremic syndrome

Current Opinion in Hematology, 2010
The last few years revealed a molecular distinction between thrombotic thrombocytopenic purpura, a disease characterized by a lack of ADAMTS13 activity, and atypical hemolytic uremic syndrome (aHUS), a disease of complement overactivation. Many different predisposing genetic factors resulting in complement overactivation have been described in aHUS ...
Kavanagh D, Goodship THJ
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Atypical Hemolytic–Uremic Syndrome

New England Journal of Medicine, 2009
The hemolytic–uremic syndrome, which is characterized by nonimmune hemolytic anemia, thrombocytopenia, and renal impairment, occurs most frequently in young children. Most cases are secondary to infection with Escherichia coli O157:H7 and other Shiga-toxin–producing strains.
Marina Noris, Giuseppe Remuzzi
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An Atypical Case of Atypical Hemolytic Uremic Syndrome

Journal of Pediatric Hematology/Oncology, 2019
We present the case of a 2-month-old infant presenting with pallor and laboratory results showing: hemoglobin 5.1 (10 to 1.5) g/dL, MCV 94.7 (75 to 105) fL, leukocytes 17.4 (7 to 15) ×103/μL, platelets 259 (150 to 450) ×103/μL, hyperbilirubinemia and renal dysfunction.
Johan Vande Walle, Evelyn Dhont, Tine François, Werner Keenswijk   +3 more
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Eculizumab for Atypical Hemolytic Uremic Syndrome in Pregnancy

Obstetrics & Gynecology, 2013
Atypical hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy often caused by mutations in complement genes. During pregnancy, disease outcome is poor both for mother and fetus. Since 2009, the humanized monoclonal antibody eculizumab has been successfully used in the treatment of atypical HUS in nonpregnant patients.A 26-year-old woman with
G. Ardissino, M. W. Ossola, G.M. Baffero, A. Rigotti, M. Cugno   +4 more
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Skin Involvement in Atypical Hemolytic Uremic Syndrome

American Journal of Kidney Diseases, 2014
Skin involvement in atypical hemolytic uremic syndrome (aHUS) is very uncommon and therefore often unrecognized as a specific symptom of aHUS. We describe 3 cases of patients with aHUS who developed skin lesions that completely recovered when disease-specific treatment was established.
ARDISSINO, GIAN LUIGI, F. Tel, S. Testa, A. V. Marzano, R. Lazzari, S. Salardi, A. Edefonti   +6 more
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Hypertensive choroidopathy in atypical hemolytic-uremic syndrome

European Journal of Ophthalmology, 2019
Purpose: We present the case of a 22-year-old woman, diagnosed as having atypical hemolytic uremic syndrome with a hypertensive crisis, who presented a bilateral serous retinal detachment. Case Description: A 22-year-old woman, diagnosed as having atypical hemolytic uremic syndrome, was referred for blurred vision in both eyes, evolving over 7 days ...
Polito M. S., Machetta F., Fea A. M., Eandi C. M.   +3 more
openaire   +4 more sources