Results 281 to 290 of about 24,341 (292)

Atypical hemolytic uremic syndrome in the Tunisian population

International Urology and Nephrology, 2010
Hemolytic uremic syndrome consists of a triad of acquired hemolytic anemia, thrombocytopenia and renal failure.Our objectives were to determine epidemiology, clinical and laboratory characteristics of patients with atypical hemolytic uremic syndrome (aHUS) to determine the relationship between the complement protein deficit and aHUS in the Tunisian ...
Pilar Sánchez-Corral, Habib Skhiri, Jemni Ben Chibani, Amel Haj Khelil, Abdellatif Achour, Nadia Leban, Mezri Elmay, Dalel Touati, Gérard Lefranc, Margarita López-Trascasa, Ramzy Lakhdhar, Sabra Aloui   +11 more
openaire   +3 more sources

Real-world safety profile of eculizumab in patients with paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, or generalized myasthenia gravis: an integrated analysis of post-marketing surveillance in Japan

International journal of hematology, 2023
J. Nishimura, T. Kawaguchi, Shuichi Ito, H. Murai, Akihiko Shimono, Takahisa Matsuda, Yuji Fukamizu, H. Akiyama, H. Hayashi, T. Nakano, S. Maruyama   +10 more
semanticscholar   +1 more source

Refractory Atypical Hemolytic Uremic Syndrome

Blood, 2012
Abstract Abstract 4635 Atypical hemolytic uremic syndrome is a rare but often lethal disease if not diagnosed and treated early. The mainstay of treatment has been plasma exchange, though eculizumab has recently been approved for treatment.
Rebecca Redman, Beth C. Riley, Ju-Hsien Chao   +2 more
openaire   +2 more sources

Atypical hemolytic uremic syndrome: a clinical conundrum

Pediatric Nephrology, 2016
Patients negative for Shiga toxin-producing E. coli (STEC) are categorized as having atypical hemolytic uremic syndrome (HUS) and are associated with an increased risk for complement mutations and poorer prognosis compared with typical HUS. However, STEC identification is limited by the natural history of HUS.The current study is aimed at identifying ...
Rossana Baracco, Amrish Jain, Gaurav Kapur, Prabesh Bajracharya, Tej K. Mattoo   +4 more
openaire   +3 more sources

Posttransplant recurrence of atypical hemolytic uremic syndrome

Journal of Nephrology, 2012
Hemolytic uremic syndrome (HUS) is a rare disease characterized by microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. It is usually secondary to infections by strains of Escherichia coli (STEC) that produce Shiga-like toxin. In about 10% of patients, no STEC infections are reported.
Marta Alberti, Marina Noris, Elisabetta Valoti   +2 more
openaire   +2 more sources

Atypical hemolytic uraemic syndrome

Medicina Clínica (English Edition), 2015
The hemolytic uremic syndrome (HUS) is a clinical entity characterized by thrombocytopenia, non-immune hemolytic anemia and renal impairment. Kidney pathology shows thrombotic microangiopathy (TMA) with endothelial cell injury leading to thrombotic occlusion of arterioles and capillaries.
Miquel Blasco Pelicano, Josep M. Campistol Plana, Santiago Rodríguez de Córdoba   +2 more
openaire   +3 more sources

Eculizumab treatment of atypical hemolytic uremic syndrome

Expert Opinion on Orphan Drugs, 2012
Introduction: This review focuses on the use of an orphan drug eculizumab (Soliris®; Alexion Pharmaceuticals Inc.), for the treatment of an extremely rare disease, atypical hemolytic uremic syndrome (aHUS). aHUS is associated with very high mortality and morbidity rates.
Lawrence Copelovitch, Rebecca L. Ruebner, Bernard S. Kaplan   +2 more
openaire   +2 more sources

Systematic review of atypical hemolytic uremic syndrome biomarkers

Pediatric nephrology (Berlin, West), 2022
R. Raina, S. Sethi, M. Dragon-Durey, Amrit Khooblall, Divya Sharma, P. Khandelwal, R. Shapiro, O. Boyer, H. Yap, A. Bagga, C. Licht   +10 more
semanticscholar   +1 more source

The treatment of atypical hemolytic uremic syndrome with eculizumab in pediatric patients: a systematic review

Pediatric nephrology (Berlin, West), 2022
Raquel Medeiros de Souza, B. H. M. Correa, P. H. M. Melo, P. A. Pousa, Tamires Sara Campos de Mendonça, Lucas Gustavo Castelar Rodrigues, A. C. Simões e Silva   +6 more
semanticscholar   +1 more source

An international consensus approach to the management of atypical hemolytic uremic syndrome in children

Pediatric nephrology (Berlin, West), 2015
C. Loirat, F. Fakhouri, G. Ariceta, N. Beşbaş, M. Bitzan, A. Bjerre, R. Coppo, F. Emma, Sally Johnson, D. Karpman, D. Landau, C. Langman, Anne-Laure Lapeyraque, C. Licht, C. Nester, C. Pecoraro, M. Riedl, N. Kar, J. Walle, M. Vivarelli, V. Frémeaux-Bacchi, F. International   +21 more
semanticscholar   +1 more source