Results 91 to 100 of about 173,798 (150)

Four types of scrapie in goats differentiated from each other and bovine spongiform encephalopathy by biochemical methods

Veterinary Research, 2019
Scrapie in goats has been known since 1942, the archetype of prion diseases in which only prion protein (PrP) in misfolded state (PrPSc) acts as infectious agent with fatal consequence.
Jan P. M. Langeveld, Laura Pirisinu, Jorg G. Jacobs, Maria Mazza, Isabelle Lantier, Stéphanie Simon, Olivier Andréoletti, Cristina Acin, Elena Esposito, Christine Fast, Martin Groschup, Wilfred Goldmann, John Spiropoulos, Theodoros Sklaviadis, Frederic Lantier, Loukia Ekateriniadou, Penelope Papasavva-Stylianou, Lucien J. M. van Keulen, Pier-Luigi Acutis, Umberto Agrimi, Alex Bossers, Romolo Nonno   +21 more
doaj   +1 more source

Scientific report on the analysis of the 2-year compulsory intensified monitoring of atypical scrapie. [PDF]

EFSA J, 2021
European Food Safety Authority (EFSA), Arnold M, Ru G, Simmons M, Vidal-Diez A, Ortiz-Pelaez A, Stella P.   +6 more
europepmc   +1 more source

The European Union summary report on surveillance for the presence of transmissible spongiform encephalopathies (TSEs) in 2017

EFSA Journal, 2018
This report presents the results of surveillance on transmissible spongiform encephalopathies (TSEs) in bovine animals, sheep, goats, cervids and other animal species, as well as genotyping in sheep, carried out in 2017 in the European Union (EU ...
European Food Safety Authority (EFSA)
doaj   +1 more source

Surveillance and simulation of bovine spongiform encephalopathy and scrapie in small ruminants in Switzerland

BMC Veterinary Research, 2010
Background After bovine spongiform encephalopathy (BSE) emerged in European cattle livestock in 1986 a fundamental question was whether the agent established also in the small ruminants' population.
Zurbriggen Andreas, Nentwig Alice, Oevermann Anna, Schwermer Heinzpeter, Häusermann Chantal, Heim Dagmar, Seuberlich Torsten   +6 more
doaj   +1 more source

Molecular Barriers to Zoonotic Transmission of Prions

Emerging Infectious Diseases, 2014
The risks posed to human health by individual animal prion diseases cannot be determined a priori and are difficult to address empirically. The fundamental event in prion disease pathogenesis is thought to be the seeded conversion of normal prion protein
Marcelo A. Barria, Aru Balachandran, Masanori Morita, Tetsuyuki Kitamoto, Rona Barron, Jean Manson, Richard Knight, James W. Ironside, Mark W. Head   +8 more
doaj   +1 more source

A single amino acid residue in bank vole prion protein drives permissiveness to Nor98/atypical scrapie and the emergence of multiple strain variants. [PDF]

PLoS Pathog, 2022
Pirisinu L, Di Bari MA, D'Agostino C, Vanni I, Riccardi G, Marcon S, Vaccari G, Chiappini B, Benestad SL, Agrimi U, Nonno R.   +10 more
europepmc   +1 more source

Circulation of Nor98 Atypical Scrapie in Portuguese Sheep Confirmed by Transmission of Isolates into Transgenic Ovine ARQ-PrP Mice. [PDF]

Int J Mol Sci, 2021
Casanova M, Machado C, Tavares P, Silva J, Fast C, Balkema-Buschmann A, Groschup MH, Orge L.   +7 more
europepmc   +1 more source

Epidemiological and genetical differences between classical and atypical scrapie cases

, 2007
The aim of this study was to analyze the epidemiology and prion protein (PrP) genetics in scrapie-affected sheep flocks in Germany. For this purpose, 224 German scrapie cases in sheep diagnosed between January 2002 and February 2006 were classified as
Georg Erhardt, Martin H. Groschup, Lühken, Gesine, Erhardt, Georg, Horst Brandt, Groschup, Martin, Eiden, Martin, Martin Eiden, Anne Buschmann, Buschmann, Anne, Brandt, Horst, Gesine Lühken   +11 more
core   +1 more source

Scientific Opinion on the evaluation of new TSE rapid tests submitted in the framework of the Commission Call for expression of interest 2007/S204‐247339

EFSA Journal, 2012
In order to be approved for use for TSE monitoring in the EU, new TSE rapid tests need to go through a specific evaluation procedure. The first three evaluation programmes were completed in 1999, 2002 and 2004.
EFSA Panel on Biological Hazards (BIOHAZ)
doaj   +1 more source

PrP genotypes of atypical scrapie cases in Great Britain

, 2006
Great Britain and elsewhere have detected atypical scrapie infection in sheep with PrP genotypes thought to be genetically resistant to the classical form of scrapie.
Mountjoy, S. J., Windl, O., Saunders, G. C., Cawthraw, S., Hope, J.   +4 more
core   +1 more source