Results 81 to 90 of about 1,645,147 (283)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Density functional theory and DFT+U study of transition metal porphines adsorbed on Au(111) surfaces and effects of applied electric fields

, 2006
We apply Density Functional Theory (DFT) and the DFT+U technique to study the adsorption of transition metal porphine molecules on atomistically flat Au(111) surfaces.
Batista, Victor S., Chandross, Michael E., Leung, Kevin, Medforth, Craig J., Rempe, Susan B., Schultz, Peter A., Sproviero, Eduardo M.   +6 more
core   +1 more source

Relaxation and reconstruction on (111) surfaces of Au, Pt, and Cu [PDF]

, 2003
We have theoretically studied the stability and reconstruction of (111) surfaces of Au, Pt, and Cu. We have calculated the surface energy, surface stress, interatomic force constants, and other relevant quantities by ab initio electronic structure ...
A.R. Sandy, B. Hammer, C.E. Bach, Ch. Wöll, D. Šokčević, F.C. Frank, G. Grübel, H. Bulou, H. Ibach, I. Galanakis, I. Galanakis, J. Frenkel, J.C. Boettger, L. Vitos, M. Bott, M. Hohage, M. Mansfield, N. Materer, N. Takeuchi, P. Lazić, R. Brako, R. Ravelo, R.J. Needs, S. Narasimhan, U. Harten, V. Repain, W. Haiss, Ž. Crljen   +27 more
core   +2 more sources

Melamine Structures on the Au(111) Surface

The Journal of Physical Chemistry C, 2008
We report on a joint experimental and theoretical study of the ordered structures of melamine molecules formed on the Au(111)-(22 x root 3) surface. Scanning tunneling microscopy (STM) images taken under UHV conditions reveal two distinct monolayers one of which has never been reported before on gold.
Fabien Silly, Adam Q. Shaw, Martin R. Castell, G. A. D. Briggs, Manuela Mura, Natalia Martsinovich, Lev Kantorovich   +6 more
openaire   +4 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Thioglycolic acid on the gold (111) surface and Raman vibrational spectra

, 2010
The interaction of thioglycolic acid with the Au(111) surface is investigaged, and it is found that at the low coverage the molecule lies down on the substrate.
Williams, Quinton L., Wu, Ruqian, Zhou, Jian-Ge   +2 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Germanene: a novel two-dimensional Germanium allotrope akin to Graphene and Silicene [PDF]

, 2014
Using a gold (111) surface as a substrate we have grown in situ by molecular beam epitaxy an atom-thin, ordered, two-dimensional multi-phase film. Its growth bears strong similarity with the formation of silicene layers on silver (111) templates.
Cahangirov, S., Dávila, M. E., Lay, G. Le, Rubio, A., Xian, L.   +4 more
core   +4 more sources

Imaging of Electron Potential Landscapes on Au(111) [PDF]

Physical Review Letters, 2002
The Hohenberg-Kohn theorem states that the ground state electron density completely determines the external potential acting on an electron system. Inspired by this fundamental theorem, we developed a novel approach to map directly the electron potential in surface systems: linear response theory applied to the total electron density as measured with ...
Bürgi, L., Brune, H., Kern, K.
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source