Results 121 to 130 of about 2,098,315 (321)

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Satellite observations of type 3 solar radio bursts at low frequencies [PDF]

Type III solar radio bursts were observed from 10 MHz to 10 KHz by satellite experiments above the terrestrial plasmasphere. Solar radio emission in this frequency range results from excitation of the interplanetary plasma by energetic particles ...
Fainberg, J., Stone, R. G.
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Anticancer Activity against Brain Cancer Using Ni (II), Cu (II), Pd (II) and Au (III) Complexes Derived from Novel Mannich Base

, 2023
Tamara Q. Manhee, Ammar J. Alabdali, N Farrell, A Lyka, C Verma, M Hossain, A Nanda, K Ali, A Alimuddin, W Zafar, S Sumrra, Z Chohan, C Prasanna, A Sharma, K Maria, H.-L Dimitra, G Maria, A El-Gendy, H El-Banna, E Buravlev, I Abdel-Rahman, H Patel, K Patel, H Patel, C Kalaivanan, N Zulfareen, A Al-Shammari, Y Liu, C Spinu, A Kriza, T Yousef, G Abu El-Reash, R Morshedy, P Panchal, S Shupack, B Bosnich, Jeslin Kanaga Inba, P   +37 more
openalex   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Cyclometalated (N,C) Au(III) Complexes: The Impact of Trans Effects on Their Synthesis, Structure, and Reactivity. [PDF]

Acc Chem Res, 2023
Holmsen MSM, Nova A, Tilset M.
europepmc   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Selective hydrometallurgical recovery of gold by using low-cost biomass waste: Kiwi peel

Adsorption Science & Technology
Utilization of kiwi peel (KP) is proposed for gold recovery from electronic wastes (e-wastes). KP was simply modified by dehydration pretreatment with concentrated sulfuric acid.
Dan Yu, Xiaomei Guo, Yang Liu
doaj   +1 more source

Crystal structures of seven mixed-valence gold compounds of the form [(R1R2R3PE)2AuI]+[AuIIIX4]− (R = tert-butyl or isopropyl, E = S or Se, and X = Cl or Br)

Acta Crystallographica Section E: Crystallographic Communications
During our studies of the oxidation of gold(I) complexes of trialkylphosphane chalcogenides, general formula R1R2R3PEAuX, (R = tert-butyl or isopropyl, E = S or Se, X = Cl or Br) with PhICl2 or elemental bromine, we have isolated a set of seven mixed ...
Daniel Upmann, Dirk Bockfeld, Peter G. Jones, Eliza Târcoveanu   +3 more
doaj   +1 more source