Results 11 to 20 of about 23,203 (49)
Nature Communications, 2022 The authors developed an optical imaging approach for mapping cortical functions through the intact skull in marmoset monkeys. Detailed functions and topographies were revealed in visual, auditory, and somatosensory cortices at mesoscopic scales.
Xindong Song +7 more
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Frontiers in Aging Neuroscience, 2012 Older adults frequently complain that while they can hear a person talking, they cannot understand what is being said; this difficulty is exacerbated by background noise. Peripheral hearing loss cannot fully account for this age-related decline in speech-
Alexandra eParbery-Clark +10 more
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Music training relates to the development of neural mechanisms of selective auditory attention
Developmental Cognitive Neuroscience, 2015 Selective attention decreases trial-to-trial variability in cortical auditory-evoked activity. This effect increases over the course of maturation, potentially reflecting the gradual development of selective attention and inhibitory control.
Dana L. Strait +3 more
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μLED‐based optical cochlear implants for spectrally selective activation of the auditory nerve
EMBO Molecular Medicine, 2020 Electrical cochlear implants (eCIs) partially restore hearing and enable speech comprehension to more than half a million users, thereby re‐connecting deaf patients to the auditory scene surrounding them.
Alexander Dieter +10 more
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Computational and Structural Biotechnology Journal, 2022 When hearing fails, electrical cochlear implants (eCIs) partially restore hearing by direct stimulation of spiral ganglion neurons (SGNs). As light can be better confined in space than electrical current, optical CIs (oCIs) provide more spectral ...
Lakshay Khurana +3 more
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Neural Plasticity, 2021 Throughout life, sensory systems adapt to the sensory environment to provide optimal responses to relevant tasks. In the case of a developing system, sensory inputs induce changes that are permanent and detectable up to adulthood.
Kateryna Pysanenko +5 more
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Frontiers in Molecular Neuroscience, 2021 Optogenetic stimulation of type I spiral ganglion neurons (SGNs) promises an alternative to the electrical stimulation by current cochlear implants (CIs) for improved hearing restoration by future optical CIs (oCIs).
Antoine Tarquin Huet +13 more
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Near physiological spectral selectivity of cochlear optogenetics
Nature Communications, 2019 Cochlear implant spectral resolution is limited by current spread from each stimulation electrode. Here the authors compare optogenetic, electric and acoustic stimulation in gerbils and demonstrate improved spectral resolution of optogenetic over ...
Alexander Dieter +4 more
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RIM-Binding Proteins Are Required for Normal Sound-Encoding at Afferent Inner Hair Cell Synapses
Frontiers in Molecular Neuroscience, 2021 The afferent synapses between inner hair cells (IHC) and spiral ganglion neurons are specialized to faithfully encode sound with sub-millisecond precision over prolonged periods of time.
Stefanie Krinner +10 more
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Towards the optical cochlear implant: optogenetic approaches for hearing restoration
EMBO Molecular Medicine, 2020 Cochlear implants (CIs) are considered the most successful neuroprosthesis as they enable speech comprehension in the majority of half a million CI users suffering from sensorineural hearing loss.
Alexander Dieter +2 more
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