Results 71 to 80 of about 2,874,302 (373)

Serotonergic Modulation of Sensory Representation in a Central Multisensory Circuit Is Pathway Specific

Cell Reports, 2017
Many studies have explored how neuromodulators affect synaptic function, yet little is known about how they modify computations at the microcircuit level.
Zheng-Quan Tang, Laurence O. Trussell
doaj   +1 more source

Hearing Without Ears [PDF]

, 2014
We report on on-going work investigating the feasibility of using tissue conduction to evince auditory spatial perception. Early results indicate that it is possible to coherently control externalization, range, directionality (including elevation ...
Lennox, Peter, McKenzie, Ian, Wiggins, Bruce   +2 more
core   +2 more sources

Drug-induced stress granule formation protects sensory hair cells in mouse cochlear explants during ototoxicity [PDF]

, 2019
Stress granules regulate RNA translation during cellular stress, a mechanism that is generally presumed to be protective, since stress granule dysregulation caused by mutation or ageing is associated with neurodegenerative disease.
Dawson, Sally J., Gale, Jonathan E., Gonçalves, Ana Cláudia, Haq, Naila, Pelletier, Jerry, Porco, John A., Towers, Emily R.   +6 more
core   +2 more sources

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

Molecular Regulation of Auditory Hair Cell Death and Approaches to Protect Sensory Receptor Cells and/or Stimulate Repair Following Acoustic Trauma

Frontiers in Cellular Neuroscience, 2015
Loss of auditory sensory hair cells is the most common cause of hearing loss. This review addresses the signaling pathways that are involved in the programmed and necrotic cell death of auditory hair cells that occur in response to ototoxic and traumatic
Christine T DINH, Stefania eGONCALVES, Esperanza eBAS, Thomas R VAN DE WATER, Azel eZINE, Azel eZINE   +5 more
doaj   +1 more source

The frontoparietal multiple demand network interacts with the dual pathways in auditory working memory [PDF]

, 2023
Ada W. S. Leung, Sylvain Moreno, Claude Alain   +2 more
openalex   +1 more source

Ascending projections to the medial geniculate body of the cat: evidence for multiple, parallel auditory pathways through thalamus

Journal of Neuroscience, 1983
The sources of ascending input to the medial geniculate body (MGB) of the cat were studied using the retrograde transport of horseradish peroxidase (HRP).
M Calford, L. Aitkin
semanticscholar   +1 more source

Neurobiology of dyslexia : A reinterpretation of the data [PDF]

, 2004
Theories of developmental dyslexia differ on how to best interpret the great variety of symptoms (linguistic, sensory, motor) observed in dyslexic individuals. One approach views dyslexia as a specific phonological deficit, which sometimes co-occurs with
Ramus, Franck
core   +4 more sources

Intertidal Warfare: Synergistic Allelopathy Mediates Spatial Competition between Two Marine Calcareous‐Shelled Sessile Organisms

Advanced Science, EarlyView.
This study reveals a hidden chemical weapon among calcareous‐shelled sessile organisms in the intertidal zone: the barnacle Balanus albicostatus releases a synergistic blend of palmitic acid and 1‐palmitoyl‐sn‐glycero‐3‐phosphocholine as the allelochemical with the inhibitory activity against attachment of the mussel Vignadula atrata, which may mediate
Zhuo Li, Zixin Huo, Shanshan Yao, Xianmeng Liang, Yiran Zhao, Yanxin Wang, Shifeng Guo, Caihuan Ke, Pei Su, Danqing Feng   +9 more
wiley   +1 more source

The Corticofugal Effects of Auditory Cortex Microstimulation on Auditory Nerve and Superior Olivary Complex Responses Are Mediated via Alpha-9 Nicotinic Receptor Subunit.

PLoS ONE, 2016
Background and objectiveThe auditory efferent system is a complex network of descending pathways, which mainly originate in the primary auditory cortex and are directed to several auditory subcortical nuclei.
Cristian Aedo, Gonzalo Terreros, Alex León, Paul H Delano   +3 more
doaj   +1 more source