Results 11 to 20 of about 2,158,008 (249)

Lung transplant outcomes for recipients with alpha-1 antitrypsin deficiency, by use of alpha-1 antitrypsin augmentation therapy

JHLT Open
Background: For patients with alpha-1 antitrypsin (AAT) deficiency, AAT augmentation therapy can be an important part of care. However, for those who require a lung transplant (LT), there is currently only limited information to guide the use of AAT ...
Atharv V. Oak, MEng, Jessica M. Ruck, MD, PhD, Alfred J. Casillan, MD, PhD, Armaan F. Akbar, BS, Ramon A. Riojas, MD, PhD, Pali D. Shah, MD, Jinny S. Ha, MD, MHS, Sara Strout, PharmD, Allan B. Massie, PhD, Dorry L. Segev, MD, PhD, Christian A. Merlo, MD, MPH, Errol L. Bush, MD   +11 more
doaj   +3 more sources

Alpha-1 antitripsyn deficiency and augmentation therapy in pregnancy: two case reports

Frontiers in Medicine
Alpha-1 antitrypsin deficiency (AATD) is an inherited condition characterized by reduced plasma levels of alpha-1 antitrypsin (AAT), often leading to pulmonary diseases primarily emphysema and/or chronic obstructive pulmonary disease (COPD), but also ...
Anna Annunziata, Giuseppe Fiorentino, Antonietta Coppola, Rosa Cauteruccio, Laura Ferrentino, Luigi Fiorentino, Cecilia Calabrese   +6 more
doaj   +3 more sources

Alpha-1 Antitrypsin Augmentation Therapy

COPD: Journal of Chronic Obstructive Pulmonary Disease, 2013
The therapy of alpha-1 antitrypsin deficiency (AATD) is an example of a medical triumph over a common hereditary disease. Based on the understanding of the pathogens of the disease as a deficiency in liver production of alpha-1 antitrypsin (AAT) resulting from inherited genetic variation in both parental AAT genes, the knowledge that A1AT functions ...
Ronald Crystal, Mark Wewers
exaly   +3 more sources

Augmentation therapy in alpha-1 antitrypsin deficiency: advances and controversies

Therapeutic Advances in Respiratory Disease, 2010
Alpha-1 antitrypsin (AAT) deficiency is a hereditary condition characterized by low levels of AAT in plasma and hence diffusion into tissues. One of the most relevant characteristics of the disease is the development of panacinar emphysema due to an ...
Adriano R. Tonelli, Mark L. Brantly
doaj   +3 more sources

Memantine as an Augmentation Therapy for Anxiety Disorders

Case Reports in Psychiatry, 2012
Objective. Glutamate, an excitatory neurotransmitter in the central nervous system (CNS), may play a role in the development of anxiety. Memantine partially blocks N-methyl-D-aspartate (NMDA) receptors' glutamate channels located in the CNS.
Thomas L. Schwartz, Umar A. Siddiqui, Shafi Raza   +2 more
doaj   +3 more sources

Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency

Biologics: Targets & Therapy, 2009
Irina Petrache1, Joud Hajjar1, Michael Campos21Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA; 2Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Miller School of Medicine ...
Irina Petrache, Joud Hajjar, Michael Campos   +2 more
doaj   +1 more source

D-cycloserine augmentation in behavioral therapy for obsessive-compulsive disorder: a meta-analysis

Drug Design, Development and Therapy, 2015
Jing Xia,1 Yanqiu Du,2 Jiyang Han,1 Guo Liu,1 Xumei Wang11Department of Psychiatry, Shengjing Hospital of China Medical University, Heping District Shenyang, Liaoning, People’s Republic of China; 2Department of Medicine, Shenyang Ninth People’
Xia J, Du Y, Han J, Liu G, Wang X
doaj   +1 more source

α1 Antitrypsin deficiency: current best practice in testing and augmentation therapy

Therapeutic Advances in Respiratory Disease, 2014
α1 Antitrypsin deficiency (AATD) increases the risk of chronic obstructive pulmonary disease (COPD), liver disease and other conditions. Although it is not a rare disease, it is a condition rarely diagnosed because of unawareness by most healthcare ...
Michael A. Campos, Jorge Lascano
doaj   +2 more sources

Atypical antipsychotics as augmentation therapy in anorexia nervosa. [PDF]

PLoS ONE, 2015
Anorexia nervosa (AN) is a life-threatening and difficult to treat mental illness with the highest mortality rates of any psychiatric disorder. We aimed to garner preliminary data on the real-world use of olanzapine and aripiprazole as augmentation ...
Enrica Marzola, Nadia Desedime, Cristina Giovannone, Federico Amianto, Secondo Fassino, Giovanni Abbate-Daga   +5 more
doaj   +3 more sources

Cellular immunity augmentation in mainstream oncologic therapy

Cancer Biology & Medicine, 2017
Anticancer immunotherapy has undergone a long evolving journey for decades, and has been dramatically applied to mainstream treatments in oncology in recent 5 years. This progress represents an advanced milestone following cytotoxic medicine and targeted
Daohong Chen, Xiaoshi Zhang
doaj   +4 more sources