Results 31 to 40 of about 2,158,008 (249)

Liver-directed SERPINA1 gene therapy attenuates progression of spontaneous and tobacco smoke-induced emphysema in α1-antitrypsin null mice [PDF]

, 2022
α1-antitrypsin deficiency is a rare genetic condition that can cause liver and/or lung disease. There is currently no cure for this disorder, although repeated infusions of plasma-purified protein may slow down emphysema progression.
Zieger, Marina, Greer, Cynthia, Flotte, Terence R, Mueller, Christian, Borel, Florie, Blackwood, Meghan, Gernoux, Gwladys   +6 more
core   +1 more source

Alpha-1 Antitrypsin Augmentation Therapy Improves Survival in Severely Deficient Patients with Predicted FEV1 Between 10% and 60%: A Retrospective Analysis of the NHLBI Alpha-1 Antitrypsin Deficiency Registry

International Journal of COPD, 2020
Franck F Rahaghi,1 Richard Monk,2 Viswanathan Ramakrishnan,3 Tatsiana Beiko,2 Charlie Strange2 1Department of Pulmonary and Critical Care, Cleveland Clinic Florida, Weston, FL, USA; 2Division of Pulmonary, Critical Care, Allergy and Sleep Medicine ...
Rahaghi FF, Monk R, Ramakrishnan V, Beiko T, Strange C   +4 more
doaj  

Management of lung disease in alpha-1 antitrypsin deficiency: what we do and what we do not know

Therapeutic Advances in Chronic Disease, 2021
Management of lung disease in patients with alpha-1 antitrypsin deficiency (AATD) includes both non-pharmacological and pharmacological approaches. Lifestyle changes with avoidance of environmental pollutants, including tobacco smoke, improving exercise ...
Igor Barjaktarevic, Michael Campos
doaj   +1 more source

Image augmentation techniques for convolutional neural network [PDF]

, 2022
openUna delle più grandi sfide per le Reti Neurali Convoluzionali, soprattutto ora che vengono utilizzate ampiamente in svariati contesti, è la mancanza di training set adeguati per sessioni di training robuste e meno prone ad overfitting.
BRAVIN, RICCARDO
core  

Progression and Augmentation Therapy in PiSZ and PiZZ Alpha-1 Antitrypsin Deficiency: A Longitudinal Functional and Densitometric Study

Biomolecules
Background: Alpha-1 antitrypsin deficiency (AATD) is a genetic disorder associated with an increased risk of developing chronic obstructive pulmonary disease (COPD) with variable phenotypic expression among different genotypes. While the PiZZ genotype is
Soha Esmaili, Juan Luis Rodríguez Hermosa, Gianna Vargas Centanaro, José Luis Álvarez-Sala, Iman Esmaili, Myriam Calle Rubio   +5 more
doaj   +1 more source

Frequency and Pattern of Worldwide Ocular Gene Therapy Clinical Trials up to 2022

Biomedicines, 2023
The purpose of this study is to describe worldwide gene therapy clinical trials aimed at treating ophthalmic disorders. Information regarding all worldwide clinical trials was collected through 15 different sources, including ClinicalTrials.gov.
Hossein Ameri, Niranjana Kesavamoorthy, Dara N. Bruce   +2 more
doaj   +1 more source

Recommendations for the Implementation of the Self-Administration of Alpha-1 Antitrypsin

International Journal of COPD, 2023
María Torres-Durán,1 José Luis López-Campos,2,3 Myriam Calle Rubio,4 Carmen Montero-Martínez,5 Ana Priegue Carrera,6 Rosanel Amaro Rodríguez,7 Miriam Barrecheguren,8 María Ángeles Barrio Guirado,9 Francisco Javier Callejas-González,10 Francisco Casas ...
Torres-Durán M, López-Campos JL, Calle Rubio M, Montero-Martínez C, Priegue Carrera A, Amaro Rodríguez R, Barrecheguren M, Barrio Guirado MA, Callejas-González FJ, Casas-Maldonado F, Diab-Cáceres L, García-Meseguer P, Hernández-Pérez JM, Lázaro-Asegurado L, Martínez-González C, Martínez Rivera C, Michel FJ, Montoro-Ronsano JB, Sánchez R, Ortiz-Pica M, Parra I, Quintero García JP, Ruiz-Serrano-de la Espada MDR, Tortajada-Goitia B, Miravitlles M   +24 more
doaj  

Impact of heterogeneities on lateral penumbra in uniform scanning proton therapy [PDF]

, 2013
Purpose: In the treatment planning of uniform scanning proton therapy, an aperture block is designed for each beam with a margin, which typically includes the lateral penumbra measured in water (homogenous) medium.
Rana, Suresh; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City, Singh, Hardev; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City   +1 more
core   +1 more source

Data augmentation approaches for polyp segmentation [PDF]

, 2022
openImage augmentation, and in general data augmentation techniques, can greatly improve the performances of deep neural networks through the creation of artificial patterns, in fact the presence of these new patterns helps the network to generalise thus
DORIZZA, ALBERTO
core  

Augmentation of Nutrition by Nanotechnology

, 2021
Nowadays, nanotechnology, by its helpful application to the food industry, has found ways for improving the health of both humans and animals. From all their benefits, we can selectively mention that nanoparticles provide antimicrobial activities and ...
Sonea, Cosmin, Mircea Lupusoru, Lupusoru, Mircea, Cosmin Sonea, Ioan Opris, Opris, Ioan   +5 more
core   +1 more source