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Genome-Wide CRISPR Screening Reveals That mTOR Inhibition Initiates Ferritinophagy and Ferroptosis in Head and Neck Cancer. [PDF]
Cancer ResKoshizuka K +11 more
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Role of thioredoxin reductase (TrxB) in oxidative stress response of <i>Francisella tularensis</i> live vaccine strain. [PDF]
J BacteriolHiggs M +4 more
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Clinics in Rheumatic Diseases, 1984
It has been widely accepted for a number of years that chrysotherapy is a valuable therapeutic agent in the treatment of progressive rheumatoid disease. This therapeutic benefit has, to some extent, been offset by the potential toxicity associated with gold compounds. The development of a gold compound with a greater therapeutic to toxicity ratio would
M, Ferrari, M T, Piro
+7 more sources
It has been widely accepted for a number of years that chrysotherapy is a valuable therapeutic agent in the treatment of progressive rheumatoid disease. This therapeutic benefit has, to some extent, been offset by the potential toxicity associated with gold compounds. The development of a gold compound with a greater therapeutic to toxicity ratio would
M, Ferrari, M T, Piro
+7 more sources
The cellular pharmacology of auranofin
Seminars in Arthritis and Rheumatism, 1987A URANOFIN (AF) [SKF 39162; (l-thioB-D-glucopyranose 2,3,4,6_tetraacetatoS)(triethylphosphine)gold], an orally active chrysotherapeutic agent, has recently been registered in 43 countries for use in the treatment of rheumatoid arthritis (RA).‘,’ Although substantial amounts of information relating to the chemical, pharmacologic, and clinical aspects of
R M, Snyder, C K, Mirabelli, S T, Crooke
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International Journal of Pharmaceutics, 1985
Abstract Two forms of auranofin, designated as A and B, have been identified. These two forms are identical in composition and differ only in their crystalline morphology. Contrary to usual expectations, form A, having the lower melting temperature, also has the lower apparent equilibrium solubility.
S LINDENBAUM +4 more
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Abstract Two forms of auranofin, designated as A and B, have been identified. These two forms are identical in composition and differ only in their crystalline morphology. Contrary to usual expectations, form A, having the lower melting temperature, also has the lower apparent equilibrium solubility.
S LINDENBAUM +4 more
openaire +1 more source
The American Journal of Medicine, 1983
Auranofin, an oral gold-containing medication for the treatment of rheumatoid arthritis, has unique chemical, pharmacologic, and kinetic characteristics. Clinical improvement is achieved with lower blood gold levels than with parenteral gold compounds.
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Auranofin, an oral gold-containing medication for the treatment of rheumatoid arthritis, has unique chemical, pharmacologic, and kinetic characteristics. Clinical improvement is achieved with lower blood gold levels than with parenteral gold compounds.
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Auranofin: Bane or bonanza for the nonrheumatologist
The American Journal of Medicine, 1983The availability of an oral gold preparation in the treatment of rheumatoid arthritis, with a claim to being effective yet safer than parenteral gold, will most certainly attract the attention of physicians and patients who previously would not have used chrysotherapy.
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