Results 101 to 110 of about 4,141 (163)

Au(III) Schiff base complexes as oxidoreductase inhibitors against carbapenem- and colistin-resistant Gram-negative bacteria via targeting redox active motifs. [PDF]

Redox Biol
Chen X, Lv L, Xu J, Shi J, Chen X, Zi G, Wu Y, Sun S, Pang Y, Song Q, Ma L, Wei S, Ma T, Liu W.   +13 more
europepmc   +1 more source

Virological and Immunological Outcomes of Combined Therapeutic Interventions and Dendritic Cell Therapy in People With HIV. [PDF]

J Infect Dis
Ndhlovu LC, Giron LB, Galinskas J, Premeaux TA, Pang APS, Dias D, de Almeida Baptista MV, Shytaj IL, Maricato JT, Ferreira PRA, Gosuen G, Corley MJ, Friday CM, Bowler SA, Della Libera E, Sucupira MC, Hunter JR, Janini LM, Schechter M, Savarino A, Diaz RS, SPARC Working Group .   +21 more
europepmc   +1 more source

Recharacterization of the Tumor Suppressive Mechanism of RSL3 Identifies the Selenoproteome as a Druggable Pathway in Colorectal Cancer. [PDF]

Cancer Res
DeAngelo SL, Zhao L, Dziechciarz S, Shin M, Solanki S, Balia A, El-Derany MO, Castillo C, Qin Y, Das NK, Bell HN, Paulo JA, Zhang Y, Rossiter NJ, McCulla EC, He J, Talukder I, Ng BW, Schafer ZT, Neamati N, Mancias JD, Koutmos M, Shah YM.   +22 more
europepmc   +1 more source

ChaC1-based drug screenings identify a synergistic lethal effect of auranofin and proteasome inhibitors in hepatocellular carcinoma cells. [PDF]

Cell Death Discov
Yu C, Liu J, Jian H, Wen B, Jiang M, Zhang B, Lin M, Lin J, Dai Z, Zhong CQ, Zheng M.   +10 more
europepmc   +1 more source

In Vitro Cytochrome P450 Interaction Profile and ADME Characterisation of Gold(I)-Triphenylphosphine Complexes with 6-Alkoxy-9-deazapurine Ligands. [PDF]

Pharmaceutics
Medvedíková M, Vančo J, Trávníček Z, Anzenbacher P.   +3 more
europepmc   +1 more source

Structure-based identification of a non-covalent thioredoxin reductase inhibitor with proven ADMET suitability. [PDF]

J Enzyme Inhib Med Chem
Lamanna G, Augello G, Ronga L, Tesauro D, Silvestri I, Azzolina A, Cervello M, Mangiatordi GF, Saviano M.   +8 more
europepmc   +1 more source

Anti-staphylococcal activity of the auranofin-analogous PEt₃AuCl: antibacterial, anti-biofilm and anti-virulence effect on clinically relevant staphylococci. [PDF]

Front Cell Infect Microbiol
Mazzantini D, Amato B, Zineddu S, de Azevedo-França JA, Maisetta G, Ghelardi E, Esin S, Messori L, Batoni G.   +8 more
europepmc   +1 more source

Thiol Scarcity in Cerebrospinal Fluid Renders Leptomeningeal Acute Lymphoblastic Leukaemia Therapeutically Vulnerable to Ferroptosis

Gajic N, Christie R, Lam S, Ackermann T, Himonas E, Josephs-Spaulding J, Manoharan A, Assmann V, Martin J, Collings A, Dunn K, Shokry E, Uribe AH, Burns S, O'Connor D, Mansour MR, Sumpton D, Helgason GV, Voorde JV, Tardito S, Tait SW, Halsey C.   +21 more
europepmc   +1 more source

The PKCι-β-arrestin2 axis disrupts SORLA retrograde trafficking, driving its degradation and amyloid pathology in Alzheimer's disease. [PDF]

Mol Neurodegener
Rehman H, Yan S, Saggu S, Aida M, Zhang F, Shu Y, Jones A, Trang A, Dew E, Zhi W, Claeboe ET, Baucum AJ, Wu G, Jiao K, Wang Q.   +14 more
europepmc   +1 more source

LC-MS Evaluation of the Redox Trypanothione Balance in <i>Leishmania infantum</i> Parasites. [PDF]

Antioxidants (Basel)
Villarubias T, Royo J, Perio P, Bourgeade-Delmas S, Sudor J, Valentin A, Terrisse AD, Reybier K.   +7 more
europepmc   +1 more source