Results 101 to 110 of about 5,328 (197)

Repurposing auranofin combined with colistin to effectively combat fish-pathogenic Edwardsiella piscicida

Aquaculture Reports
Edwardsiella piscicida (E. piscicida) is an important opportunistic fish pathogen, and infects various species of cultured fish posing a great challenge to the aquaculture industry globally.
Jinfang Lu, Yangbin Shi, Yajing Pan, Hans-Peter Grossart, Luyu Mei, Danli Xie, Wanchun Guan, He Zhang, Yongliang Lou   +8 more
doaj   +1 more source

Repurposing Approach Identifies Auranofin with Broad Spectrum Antifungal Activity That Targets Mia40-Erv1 Pathway

, 2017
Current antifungal therapies have limited effectiveness in treating invasive fungal infections. Furthermore, the development of new antifungal is currently unable to keep pace with the urgent demand for safe and effective new drugs.
Pete E. Pascuzzi, Seleem, Mohamed N, Tony R. Hazbun, Mohamed N. Seleem, Shankar Thangamani, Larisa Avramova, Maland, Matthew, Thangamani, Shankar, Matthew Maland, Carla M. Koehler, Koehler, Carla E, Hazbun, Tony R, Koehler, Carla M, Haroon Mohammad, Pascuzzi, Pete E, Avramova, Larisa, Mohammad, Haroon   +16 more
core   +1 more source

A biochemical investigation of auranofin nephrotoxicity by high field proton nuclear magnetic resonance spectroscopy

, 1991
High-field proton NMR spectroscopic analysis of urine and plasma has been employed to study the biochemical effects and nephrotoxic action of an intramuscular dose of auranofin in rats.
Grootveld, Martin, Naughton, Declan, Grootveld, M, Blake, D, Blake, David, Claxson, A, Claxson, Andrew   +6 more
core  

Auranofin and iodoquinol as promising repurposing drugs against filamentous fungi: antifungal activity and cellular alterations. [PDF]

Microbiol Spectr
Xisto MIDdS, Rollin-Pinheiro R, da Rosa PCM, Souza Santos Jd, Irmão NFdS, Abib JAA, Rochetti VP, de Castro Almeida Y, Santos Freitas GMPd, Cypriano J, Barreto-Bergter E.   +10 more
europepmc   +1 more source

Cysteine-reactive mitigators of small vessel disease-related NOTCH3 mutants. [PDF]

Sci Rep
Cartee NMP, Zhang X, Lee SJ, Wang MM.
europepmc   +1 more source

Auranofin attenuates TOPBP1-mediated ATR replication stress response and improves chemotherapeutic response in breast tumor models. [PDF]

J Clin Invest
Ma S, Han Y, Gu R, Chen Q, Guo Q, Yue Y, Cao C, Liu L, Yang Z, Qin Y, Yang Y, Zhang K, Liu F, Liu L, Yang N, Hao J, Yang J, Yao Z, Mao X, Shi L.   +19 more
europepmc   +1 more source

Correction: PRKCI mediates radiosensitivity via the Hedgehog/GLI1 pathway in cervical cancer. [PDF]

Front Oncol
Wu Z, Huang C, Li R, Li H, Lu H, Lin Z.
europepmc   +1 more source

Structure-Based Strategy Reveals a Novel Ligand Binding Site in <i>Staphylococcus aureus</i> Catabolite Control Protein A: Implications for Transcriptional Regulation and Drug Design. [PDF]

ACS Omega
Farias AB, Sisco MC, de Oliveira Cerqueira E Costa M, Perez-Rueda E, Nicolás MF.   +4 more
europepmc   +1 more source

Development of Gold Auranofin Analogues against Multidrug Resistant Bacteria Including Neisseria Gonorrhoeae [PDF]

Denne oppgaven vil presentere en gjennomgang av nyere forskning på medikamentet Auranofin,som ble godkjent av det amerikanske legemiddelverket (FDA) som et antiaritmetisk legemiddel.
Simensen, Andreas Hegland
core  

Retraction: Thioredoxin Glutathione Reductase as a Novel Drug Target: Evidence from Schistosoma japonicum. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source