Results 161 to 170 of about 8,070 (210)

Targeting the Glucose-Insulin Link in Head and Neck Squamous Cell Carcinoma Induces Cytotoxic Oxidative Stress and Inhibits Cancer Growth. [PDF]

open access: yesCancer Res Commun
Mazambani S   +17 more
europepmc   +1 more source

Auranofin

Clinics in Rheumatic Diseases, 1984
It has been widely accepted for a number of years that chrysotherapy is a valuable therapeutic agent in the treatment of progressive rheumatoid disease. This therapeutic benefit has, to some extent, been offset by the potential toxicity associated with gold compounds. The development of a gold compound with a greater therapeutic to toxicity ratio would
M, Ferrari, M T, Piro
  +7 more sources

Auranofin‐induced vasomotor reaction

Arthritis & Rheumatism, 1992
AbstractVasomoto reactions after administraton of gold sodium thiomalate (GST)are well recognized, ut such reacti9os have not bn reported to ccur in assocation woth oral gold treatment. We descrbe a woman with rheumatoid arthritis who exprienced typical nitritoid reactions after treatment with GST, and later, with auranofin.
S M, Proudman, L G, Cleland
openaire   +2 more sources

Roentgenographic findings during auranofin treatment

The American Journal of Medicine, 1983
Roentgenograms of hands and wrists from rheumatoid arthritis patients treated with auranofin for 12 and 24 months were scored for severity of erosive disease. Scores were analyzed by a method in which a calculated mean annual rate of erosion prior to treatment was compared with the annualized rate during therapy.
J P, Gofton, W, O'Brien
openaire   +2 more sources

The cellular pharmacology of auranofin

Seminars in Arthritis and Rheumatism, 1987
A URANOFIN (AF) [SKF 39162; (l-thioB-D-glucopyranose 2,3,4,6_tetraacetatoS)(triethylphosphine)gold], an orally active chrysotherapeutic agent, has recently been registered in 43 countries for use in the treatment of rheumatoid arthritis (RA).‘,’ Although substantial amounts of information relating to the chemical, pharmacologic, and clinical aspects of
R M, Snyder, C K, Mirabelli, S T, Crooke
openaire   +2 more sources

Polymorphism of auranofin

International Journal of Pharmaceutics, 1985
Abstract Two forms of auranofin, designated as A and B, have been identified. These two forms are identical in composition and differ only in their crystalline morphology. Contrary to usual expectations, form A, having the lower melting temperature, also has the lower apparent equilibrium solubility.
S LINDENBAUM   +4 more
openaire   +1 more source

Auranofin: Experience to date

The American Journal of Medicine, 1983
Auranofin, an oral gold-containing medication for the treatment of rheumatoid arthritis, has unique chemical, pharmacologic, and kinetic characteristics. Clinical improvement is achieved with lower blood gold levels than with parenteral gold compounds.
openaire   +2 more sources

Upgrade of an old drug: Auranofin in innovative cancer therapies to overcome drug resistance and to increase drug effectiveness

Medicinal Research Reviews, 2022
Tania Gamberi   +2 more
exaly  

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