Results 151 to 160 of about 1,136,055 (336)
Targeted Mitochondrial ECSIT Overexpression Attenuates MASH by Increasing OTUD3 Expression
Advanced Science, EarlyView.Mitochondrial ECSIT expression is reduced during MASH pathogenesis. Overexpression of mitochondrial ECSIT mitigates steatohepatitis and maintains hepatic metabolic homeostasis. Mechanistically, ECSIT enhances intramitochondrial OTUD3 expression to stabilize SIRT3 through deubiquitination, thus preserving mitochondrial function and impeding disease ...
Yuqing Jiang +11 more
wiley +1 more source
Leadership and the paradox of authenticity [PDF]
, 2016 This is the author version of a chapter accepted for publication by Routledge.In 2003, Bill George (former CEO of Medtronic Plc an S&P 500 constituent) argued that “Due to the current crisis, complexities and challenges facing our society and ...
Adarves-Yorno, Inmaculada
core
Advanced Science, EarlyView.Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu +8 more
wiley +1 more source
cuteHap: Haplotype‐Aware Structural Variant Detection in Phased Long‐Read Sequencing Data
Advanced Science, EarlyView.cuteHap is a haplotype‐aware structural variant detection method designed for phased long‐read sequencing. By employing self‐adaptive clustering and credibility‐prioritized beam search algorithms, cuteHap generates accurate haplotype‐resolved calls and outperforms state‐of‐the‐art tools.
Shuqi Cao +7 more
wiley +1 more source
Advanced Science, EarlyView.Inspired by the regulation mechanism of window blinds, this study designs an electromagnetic wave‐absorbing metamaterial. By introducing the magneto‐electric coupling concept and integrating it with an artificial intelligence‐based data‐driven collaborative optimization strategy, the material optimizes impedance matching performance and enhances loss ...
Zhe Wang +9 more
wiley +1 more source
Revista Brasileira de EnfermagemObjectives: to identify the dominant dimensions of the authentic leadership of nurses in a private hospital network and to verify the association with job satisfaction and accreditation.
Sonia Aparecida Batista +4 more
doaj +2 more sources
Dimensions of authentic leadership in the Middle Eastern context: Are these leaders really authentic? [PDF]
, 2016 The economic crisis and the various business scandals have placed a call for leaders who are responsible, ethical, do not deceive others,and lead in an authentic way.
Marinakou, Evangelia, Nikolic, B
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Effect of Educational Program about Authentic Leadership and Mindfulness Factors on Head Nurses Practice Self – Evaluation [PDF]
, 2020 Sabah Abd Elmawla +2 more
openalex +1 more source
Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases
Advanced Science, EarlyView.This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo +5 more
wiley +1 more source