Results 41 to 50 of about 52,259 (246)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Authentication of Insect-Based Products in Food and Feed: A Benchmark Survey

Insects
The consumption and farming of insects are gaining global attention as sustainable alternatives to conventional protein sources. Industrial processing of insects into powders or pastes complicates species identification, raising concerns about product ...
Aline Marien, Benjamin Dubois, Olivier Fumière, Abigaël Anselmo, Julien Maljean, Clémence Debailleul, Jean-François Morin, Frédéric Debode   +7 more
doaj   +1 more source

Quantification and Classification of Corn and Sunflower Oils as Adulterants in Olive Oil Using Chemometrics and FTIR Spectra

The Scientific World Journal, 2012
Commercially, extra virgin olive oil (EVOO) is subjected to be adulterated with low-price oils having similar color to EVOO. Fourier transform infrared (FTIR) spectroscopy combined with chemometrics has been successfully used for classification and ...
Abdul Rohman, Y. B. Che Man
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Authentication and authenticated key exchanges [PDF]

Designs, Codes and Cryptography, 1992
We discuss two-party mutual authentication protocols providing authenticated key exchange, focusing on those using asymmetric techniques. A simple, efficient protocol referred to as the station-to-station (STS) protocol is introduced, examined in detail, and considered in relation to existing protocols. The definition of a secure protocol is considered,
Whitfield Diffie, Paul C. Van Oorschot, Michael J. Wiener   +2 more
openaire   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

ToAM: a task-oriented authentication model for UAVs based on blockchain

EURASIP Journal on Wireless Communications and Networking, 2021
The pervasive cooperation of a group of UAVs has attracted increasing attention due to the reduced cost and widespread availability. When working in an untrusted or adversarial environment, the mutual authentication of UAVs in the cooperative process is ...
Aiguo Chen, Kun Peng, Zexin Sha, Xincen Zhou, Zhen Yang, Guoming Lu   +5 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Research on efficient cross trust-domain group authentication with conditional privacy of vehicle platoon under blockchian architecture

Tongxin xuebao, 2023
In order to balance the security and efficiency of vehicle platoon cross trust-domain identity authentication, an efficient cross trust-domain group authentication scheme with conditional privacy of vehicle platoon under blockchian architecture was ...
Yingjie XIA, Siyu ZHU, Xuejiao LIU
doaj   +2 more sources