Results 71 to 80 of about 52,259 (246)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Keyless Authentication and Authenticated Capacity
IEEE Transactions on Information Theory, 2018 We consider the problem of keyless message authentication over noisy channels in the presence of an active adversary. Different from the existing models, in our model, the legitimate users do not have any pre-shared key for authentication. Instead, we use the noisy channel connecting the legitimate users for authentication.
Wenwen Tu, Lifeng Lai
openaire +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
A Novel Protocol Using Captive Portals for FIDO2 Network Authentication
Applied SciencesFIDO2 authentication is starting to be applied in numerous web authentication services, aiming to replace passwords and their known vulnerabilities. However, this new authentication method has not been integrated yet with network authentication systems ...
Martiño Rivera-Dourado +3 more
doaj +1 more source
Research on User Identity Authentication Based on Two-way Confirmation in Data Transmission
MATEC Web of Conferences, 2018 User identity authentication is the foundation of data transmission in the complicated network environment. Moreover, the key issue is the effective identity authentication of both sides in data transmission.
Li Qin +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Al-Khawarizmi Engineering Journal, 2012 The aim of this work is to study the influence of the type of fiber glass –mat on fatigue behavior of composite material which is manufactured from polyester and E-glass (woven roving, chopped strand mat (CSM)) as a laminate with a constant fiber volume ...
Hussain J. Al-Alkawi +2 more
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source