Results 131 to 140 of about 126,557 (260)

TSTScope Unifies Single‐Cell Multi‐Omics to Identify Functional T Cell States Predictive of Immunotherapy Response

open access: yesAdvanced Science, EarlyView.
TSTScope is an interpretable AI framework that integrates single‐cell transcriptomes with TCR information through curated gene‐program constraints. By linking receptor context to functional T cell states, it reveals response‐associated tumor‐specific T cell programs in lung cancer immunotherapy cohorts and defines an MPR score associated with ...
Shiwei Cao   +8 more
wiley   +1 more source

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

open access: yesAdvanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang   +18 more
wiley   +1 more source

Benchmarking National Communications Regulatory Authority websites 2010

open access: yes, 2013
This paper provides an executive overview of the communications sector’s National Regulatory Authorities’ (NRAs’) website benchmark results for Africa in 2010, which were evaluated between March and April 2010. The analysis ranks the online component of information provision and facilitation of regulatory processes. This study follows previous regional
openaire   +1 more source

Livestock Multi‐Omics Integration: A Systematic Framework From Statistical Association to Causal Interpretation

open access: yesAdvanced Science, EarlyView.
A three‐tier livestock multi‐omics framework resolves four typical analytical pitfalls. Moving from statistical association through machine learning preprocessing to triple‐modal causal inference, it converts omics results into genomic selection and gene editing strategies to achieve One Health, underpinned by multi‐omics data, multimodal sequencing ...
Jiying Wen   +5 more
wiley   +1 more source

Benchmark indicators for African national regulatory authority websites

open access: yes, 2013
This survey of African national regulatory websites ranks the online component of information provision and facilitation of regulatory processes. This study follows a previous regional survey conducted in 2004-05 which examined the extent to which regulators were using websites to inform and communicate with the public – including consumers and ...
openaire   +1 more source

Quantum‐Like Dynamics in Whole‐Brain Models of the Human Connectome

open access: yesAdvanced Science, EarlyView.
Quantum‐like dynamics in the human brain. The level of quantum‐like behavior in a non‐quantum system of coupled oscillators is regulated by the spectral gap of the coupling graph. Whole‐brain modelling using QL fits the empirical data significantly better and has a lower model‐derived energy cost than the non‐QL model.
Gustavo Deco   +5 more
wiley   +1 more source

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