Results 161 to 170 of about 778,558 (294)

Originality, Authorship, and Accountability in AI-Enabled Pharmaceutical Design. [PDF]

Clin Pharmacol Drug Dev
Hubbard MF, M Issa A, Fossler MJ.
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Retraction: Histological Patterns of Mycophenolate Mofetil-Induced Gastrointestinal Mucosal Injury in Renal Transplant Recipients. [PDF]

Cureus
Chaudhary N, Sachan S, Ansari A, Nigam N, Rao RN, Kaul A.   +5 more
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Bilateral photic retinopathy following firework exposure. [PDF]

Am J Ophthalmol Case Rep
King TC, Lin T, Lee KAV, de Lima Farah Agi J.   +3 more
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Retraction Note: Heat transfer analysis of Cu and Al₂O₃ dispersed in ethylene glycol as a base fluid over a stretchable permeable sheet of MHD thin-film flow. [PDF]

Sci Rep
Zeeshan, Khan I, Weera W, Mohamed A.
europepmc   +1 more source

The Moral Economies of American Authorship Reputation, Scandal, and the Nineteenth-Century Literary Marketplace

The Moral Economies of American Authorship argues that the moral character of authors became a kind of literary property within mid-nineteenth-century America's expanding print marketplace, shaping the construction, promotion, and reception of texts as ...
Ryan, Susan M.
core  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Bilateral ciliary body cysts mimicking peripheral bullous retinal detachment: Diagnosis by ultrasound biomicroscopy and glaucomatous implications. [PDF]

Am J Ophthalmol Case Rep
Bounetta S, Vermot-Desroches V, Weinzaepfel E, Rahmi A, Mathis T, Kodjikian L, Denis P.   +6 more
europepmc   +1 more source