Results 41 to 50 of about 2,929,561 (349)

Autistic traits in trichotillomania

Brain and Behavior, 2022
Introduction Although many variables have been examined as potentially contributing to the manifestation of trichotillomania (TTM), little research has focused on problems in social interactions.
Jon E. Grant, Samuel R. Chamberlain
doaj   +1 more source

Network Desynchronization with Sine Waves: from Synchrony to Asynchrony by Periodic Stimulation

Advanced Science, EarlyView.
Exogenous alternating current fields are explored and interact with cerebral cortex slow waves in vitro and in silico. Varying frequency and amplitude of sine waves result in distinct network dynamics, from phase‐locking and entrainment to desynchronization. These responses occupy specific regions within the parameter space.
Joana Covelo, Martina Cortada, Gianni V. Vinci, Maurizio Mattia, Maria V. Sanchez‐Vives   +4 more
wiley   +1 more source

Role of Gut Microbiome in Autism Spectrum Disorder and Its Therapeutic Regulation

Frontiers in Cellular and Infection Microbiology, 2022
Autism spectrum disorder (ASD) is a neurological disorder that affects normal brain development. The recent finding of the microbiota–gut–brain axis indicates the bidirectional connection between our gut and brain, demonstrating that gut microbiota can ...
M. Taniya, Hea-Jong Chung, Abdullah Al Mamun, Safaet Alam, Md. Abdul Aziz, N. Emon, Md. Minarul Islam, Seokwoo Hong, B. R. Podder, Anjuman Ara Mimi, Suzia Aktar Suchi, Jian Xiao   +11 more
semanticscholar   +1 more source

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Advanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song, Yifan Wang, Lili Wang, Chang Guo, Shiqi Liu, Yi Rong, Jiawen Tian, Chao Peng, Yuying Shao, Zhixiong Ma, Na Li, Jingliang Zhang, Zijun Peng, Xu Yan, Hangwei Fa, Xinyue Ma, Jie Dong, Jinping Ji, Chen Yang, Haocheng Chen, Jing Liang, Qi Sun, Yang Yang, Weining Ma, Zhuo Huang   +24 more
wiley   +1 more source

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

Advanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich, Jing Wang, Ferdinand Althammer, Tim Schubert, Nina Kluck, Valery Grinevich, Stefanie Schmitteckert, Christian P. Schaaf, Gudrun A. Rappold   +8 more
wiley   +1 more source

Autism and ADHD in Tuberous Sclerosis

Pediatric Neurology Briefs, 1994
In a population-based psychiatric study of 28 patients with tuberous sclerosis (TS) at the University of Goteborg, Sweden, 24 had autistic symptoms and 17 met all DSM-III-R criteria for autistic disorder (AD).
J Gordon Millichap
doaj   +1 more source

Determination of Knowledge of Caregivers about Dietary Practices of Autistic Children

BioMedica, 2020
Background and Objective: Autism belongs to a complex neurodevelopmental disorder. The lack of knowledge about dietary practices of autistic caregivers is perceived as the triggering factor of ‘Autistic Spectrum Disorder (ASD).
Maryam Yaseen, Bahisht Rizwan, Iqra Gulzar, Ramsha Khalid, Sheza Tanveer, Zoya Abid, Sana Farooq   +6 more
doaj   +1 more source

The functional neuroanatomy of social behaviour: changes in cerebral blood flow when people with autistic disorder process facial expressions.

Brain : a journal of neurology, 2000
Although high-functioning individuals with autistic disorder (i.e. autism and Asperger syndrome) are of normal intelligence, they have life-long abnormalities in social communication and emotional behaviour.
Hugo D. Critchley, E. Daly, E. Bullmore, S. Williams, T. V. Amelsvoort, D. Robertson, Andrea D. Rowe, M. Phillips, G. McAlonan, P. Howlin, D. Murphy   +10 more
semanticscholar   +1 more source

Sleep Deprivation Aggravates Periodontitis Through Trigeminal‐Periodontal Neuroimmune Pathway Mediated by the AChE‐ACh‐α7nAChR Axis

Advanced Science, EarlyView.
Sleep deprivation (SD) exacerbates ligature‐induced periodontitis (LIP) through the trigeminal nerve‐periodontal neuroimmune pathway mediated by the acetylcholinesterase (AChE)‐acetylcholine (ACh)‐α7 nicotinic receptor (α7nAChR) axis. While electroacupuncture (EA) alleviates the condition of LIP combined with SD by activating the α7nAChR.
Kehao Liu, Qi Huang, Mingcong Yang, Ziyu Huang, Kamoran Tuerhong, Yue Zu, Ying Xie, Xuehui Hu, Qianyu Zhang, Ping He, Nannan Huang, Rong Zhang, Yuzhou Li, Sheng Yang   +13 more
wiley   +1 more source

The Effect of Autistic Traits on Social Orienting in Typically Developing Individuals

Frontiers in Psychology, 2020
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by wide ranging and heterogeneous changes in social and cognitive abilities, including deficits in orienting attention during early processing of stimuli. Investigators
Guoyao Lin, Guoyao Lin, Yanling Cui, Jiajing Zeng, Liang Huang   +4 more
doaj   +1 more source