Results 51 to 60 of about 912,674 (282)

A Theory of Auto-Scaling for Resource Reservation in Cloud Services

open access: yesACM SIGMETRICS Performance Evaluation Review, 2021
We consider a distributed server system consisting of a large number of servers, each with limited capacity on multiple resources (CPU, memory, disk, etc.). Jobs with different rewards arrive over time and require certain amounts of resources for the duration of their service. When a job arrives, the system must decide whether to admit it or reject it,
Konstantinos Psychas, Javad Ghaderi
openaire   +4 more sources

Towards Auto-Scaling of Serverless Data Pipelines [PDF]

open access: yes, 2023
The ever-increasing number of IoT devices generates massive data, and collecting data from heterogeneous sources and processing it without any bottleneck is challenging.
Das, Rajan Raj
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Proactive Auto-Scaling Approach of Production Applications Using an Ensemble Model

open access: yesIEEE Access, 2023
The resource usage behaviors of application workloads are currently the primary concern of cloud providers offering hosting services. These services should be able to adapt to workload changes by automatically provisioning and de-provisioning resources ...
Mohamed Samir   +2 more
doaj   +1 more source

Stream Data Load Prediction for Resource Scaling Using Online Support Vector Regression

open access: yesAlgorithms, 2019
A distributed data stream processing system handles real-time, changeable and sudden streaming data load. Its elastic resource allocation has become a fundamental and challenging problem with a fixed strategy that will result in waste of resources or a ...
Zhigang Hu, Hui Kang, Meiguang Zheng
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Cloud Resource Management With Turnaround Time Driven Auto-Scaling

open access: yesIEEE Access, 2017
Cloud resource management research and techniques have received relevant attention in the last years. In particular, recently numerous studies have focused on determining the relationship between server-side system information and performance experience ...
Xiaolong Liu   +4 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

A hybrid auto-scaling technique for clouds processing applications with service level agreements

open access: yesJournal of Cloud Computing: Advances, Systems and Applications, 2017
This research focuses on the automatic provisioning of cloud resources by an intermediary enterprise. This enterprise provides a virtual private cloud for a single client enterprise by using resources from a public cloud.
Anshuman Biswas   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy