Results 61 to 70 of about 8,251,079 (331)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Physical ageing from generalised time-translation-invariance
Nuclear Physics BA generalised form of time-translation-invariance permits to re-derive the known generic phenomenology of ageing, which arises in classical many-body systems after a quench from an initially disordered system to a temperature T≤Tc, at or below the ...
Malte Henkel
doaj +1 more source
Cloud Resource Management With Turnaround Time Driven Auto-Scaling
IEEE Access, 2017 Cloud resource management research and techniques have received relevant attention in the last years. In particular, recently numerous studies have focused on determining the relationship between server-side system information and performance experience ...
Xiaolong Liu +4 more
doaj +1 more source
Auto-scaling containerized cloud applications: a workload-driven approach
, 2022 Today, cloud computing presents new business opportunities as it offers various technological advantages including elastic computing and efficient pricing strategies. Although, cloud users have access to large amount of resources, it is yet a challenging
Sotiriadis, Stelios, Chouliaras, Spyros
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Pervasive Auto-Scaling Method for Improving the Quality of Resource Allocation in Cloud Platforms
Big Data and Cognitive ComputingCloud resource provider deployment at random locations increases operational costs regardless of the application demand intervals. To provide adaptable load balancing under varying application traffic intervals, the auto-scaling concept has been ...
Vimal Raja Rajasekar, G. Santhi
doaj +1 more source
A hybrid auto-scaling technique for clouds processing applications with service level agreements
Journal of Cloud Computing: Advances, Systems and Applications, 2017 This research focuses on the automatic provisioning of cloud resources by an intermediary enterprise. This enterprise provides a virtual private cloud for a single client enterprise by using resources from a public cloud.
Anshuman Biswas +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
TOSCA-Based and Federation-Aware Cloud Orchestration for Kubernetes Container Platform
Applied Sciences, 2019 Kubernetes, a container orchestration tool for automatically installing and managing Docker containers, has recently begun to support a federation function of multiple Docker container clusters.
Dongmin Kim +4 more
doaj +1 more source