Results 101 to 110 of about 237,743 (361)

The antibody repertoire of autoimmune sensory neuronopathies targets pathways of the innate and adaptive immune system. An autoantigenomic approach

Journal of Translational Autoimmunity
Sensory neuronopathies (SNN) encompass diverse etiologies, with autoimmunity playing a major role through both cellular and humoral responses. To investigate the humoral autoantibody repertoire in autoimmune SNN, we conducted a retrospective cohort study
Christian P. Moritz, Yannick Tholance, Nadia Boutahar, Coralie Borowczyk, Anne-Emmanuelle Berger, Stéphane Paul, Jean-Christophe Antoine, Jean-Philippe Camdessanché   +7 more
doaj  

A novel platform for isotype-specific testing of autoantibodies.

PLoS ONE, 2019
The objective of this study was to test if a novel platform could be used for isotype-specific autoantibody testing in humans. Further, we evaluated if testing with this novel platform enables earlier detection of insulin autoantibodies in individuals ...
Kaylene L Carter, Anckia Treurnicht, Kara L Davis, Rajiv B Kumar, Brian J Feldman   +4 more
doaj   +1 more source

Recognition of Glycine Versus Nonglycine Citrulline Motifs Dictating the HLA Class II Association of Anticitrullinated Protein Antibodies: Insights From Autoantibody Profiling of 6,900 Scandinavian Patients With Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA)–associated anticitrullinated protein antibodies (ACPAs) target various antigens by binding short citrulline amino acid motifs, resulting in heterogeneous ACPA profiles among patients. Here we analyzed ACPA patterns by recognized citrulline motifs in relation to the RA risk factors HLA‐DRB1 shared epitope (SE) alleles
Linda Mathsson Alm, Helga Westerlind, Isabel Gehring, Monika Hansson, Nasim Ghasemzadeh, Jessica Rojas‐Restrepo, Saedis Saevarsdottir, Joe Sexton, Siri Lillegraven, Espen Haavardsholm, Bente Glintborg, Hilde Berner Hammer, Tore K. Kvien, Merete Lund Hetland, Leonid Padyukov, Swedish Rheumatology Quality Register Biobank Study Group (SRQb), The Danish Rheumatologic Biobank Study Group, Johan Askling, Caroline Grönwall   +18 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Ageing and Autoantibodies

Autoimmunity, 1988
Immune responsiveness decreases with age, while the production of autoantibodies increases, indicating that these are end results of perturbations in the regulatory mechanisms of the immune system. The effects of ageing on the immune system are reviewed.
Yaron Tomer, Yehuda Shoenfeld
openaire   +3 more sources

Antineutrophil cytoplasmic autoantibodies in uveitis [PDF]

Acta Medica Iranica, 2000
Antineutrophil cytoplasmic autoantibodies were detected in patients with some autoimmune and vascular disease such as Wegner’s granulomatosis polyarthritis nodosa and systemic lupus erythematosus.
"Vodjgani M, Baghbani HN, Hajati J "
doaj   +2 more sources

Initial screening for neuronal autoantibodies and their putative impact on survival in patients with small‐cell lung cancer

Thoracic Cancer
Introduction Small‐cell lung cancer (SCLC) may be associated with neuronal autoantibodies and paraneoplastic neurological syndromes. It has been suggested that neuronal autoantibodies, especially antineuronal nuclear antibody type 1 (Hu) autoantibodies ...
Anne With Mikkelsen, Anna Christine Nilsson, Helene Broch Tenstad, Soeren Thue Lillevang, Nasrin Asgari   +4 more
doaj   +1 more source

Dynamic disorganization of synaptic NMDA receptors triggered by autoantibodies from psychotic patients

Nature Communications, 2017
The identification of circulating autoantibodies against neuronal receptors in neuropsychiatric disorders has fostered new conceptual and clinical frameworks.
J. Jezequel, E. Johansson, J. Dupuis, V. Rogemond, H. Gréa, Blanka Kellermayer, N. Hamdani, Emmanuel Le Guen, C. Rabu, Marilyn Lepleux, M. Spatola, Elodie Mathias, Delphine Bouchet, A. Ramsey, R. Yolken, R. Tamouza, J. Dalmau, J. Honnorat, M. Leboyer, L. Groc   +19 more
semanticscholar   +1 more source

Time‐Dependent Effect of Prophylactic Trimethoprim‐Sulfamethoxazole on the Incidence of Serious Infections in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: A Target Trial Emulation Study

Arthritis &Rheumatology, EarlyView.
Objective The objective of this study was to investigate the effect of prophylactic trimethoprim‐sulfamethoxazole (TMP‐SMX) on the incidence of serious infections in patients with antineutrophil cytoplasmic antibody–associated vasculitis (AAV). Methods This multicenter cohort study was designed to emulate a target trial that studied 296 patients with ...
Yun Kyu Kim, Jeffrey R. Curtis, Se Rim Choi, Jina Yeo, Min Jung Kim, Yun Jong Lee, Eun Bong Lee, Jun Won Park   +7 more
wiley   +1 more source

Preferential Reactivity of Dipeptidyl Peptidase-IV Inhibitor-Associated Bullous Pemphigoid Autoantibodies to the Processed Extracellular Domains of BP180

Frontiers in Immunology, 2019
Bullous pemphigoid (BP) is a common autoimmune blistering disease in which autoantibodies target the hemidesmosomal components BP180 and/or BP230 in basal keratinocytes.
Yosuke Mai, Wataru Nishie, Kentaro Izumi, Hiroshi Shimizu   +3 more
doaj   +1 more source