Results 101 to 110 of about 151,970 (246)
Arthritis &Rheumatology, EarlyView.Objective The transition from asymptomatic antinuclear antibody (ANA) positivity to systemic autoimmune rheumatic disease (SARD) is associated with increased production of proinflammatory factors such as tumor necrosis factor α (TNFα). Here we investigate whether the relative absence of inflammation in asymptomatic ANA+ individuals (ANA+NS) results ...
Carolina Muñoz‐Grajales +8 more
wiley +1 more source
CD8+ immunoregulatory cells in the graft‐versus‐host reaction: CD8 T cells activate dendritic cells to secrete interleukin‐12/interleukin‐18 and induce T helper 1 autoantibody [PDF]
, 2003 Alistair Noble +2 more
openalex +1 more source
Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease
Arthritis &Rheumatology, EarlyView.Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman +2 more
wiley +1 more source
Alu Overexpression Leads to an Increased Double‐Stranded RNA Signature in Dermatomyositis
Arthritis &Rheumatology, EarlyView.Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the noncoding genome in disease pathogenesis.
Rayan Najjar +2 more
wiley +1 more source
Nucleoprotein Autoantibodies in Lupus Erythematosus
, 1985 Thomas T. Provost +2 more
openalex +1 more source
Autoantibody formation after alloimmunization inducing bystander immune hemolysis [PDF]
, 2009 Márcia Maria Peruzzi Elia da Mota +6 more
openalex +1 more source
Arthritis &Rheumatology, EarlyView.Objective International criteria for antiphospholipid syndrome (APS) include lupus anticoagulant (LA), anticardiolipin (aCL) IgG and IgM, and anti–β2‐glycoprotein I (β2GPI) IgG and IgM. However, evidence supporting their prognostic value or treatment efficacy in improving live birth rates is limited.
Megumi Nonobe +8 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Keratinocyte‐derived interferon (IFN) κ is chronically overexpressed in human nonlesional systemic lupus erythematosus (SLE) skin. Recent evidence suggests that epidermal signals instruct the immune system in SLE, but whether epidermal IFNκ alone is sufficient to drive lupus phenotypes has not been investigated.
Benjamin Klein +14 more
wiley +1 more source
Could maternal autoantibodies against folate receptor-membrane proteins cause spontaneous abortion or congenital heart defects? [PDF]
, 2006 Alan Neuman +7 more
openalex +1 more source