Results 121 to 130 of about 237,743 (361)
Antibodies against neuronal receptors and synaptic proteins are associated with autoimmune encephalitides (AE) that produce movement and psychiatric disorders.
M. Platt, D. Agalliu, T. Cutforth
semanticscholar +1 more source
Mucosal‐Associated Invariant T Cells in Rheumatic Diseases
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek+7 more
wiley +1 more source
Environment, Autoantibodies, and Autoimmunity [PDF]
Susceptibility to autoimmune disease is multifactorial and includes genetic predisposition, gender, ethnicity, age, and environment. While no single factor has been identified as preeminent, the role of the environment has garnered increasing interest.
openaire +4 more sources
The Production of Thyroid Autoantibodies in Mice [PDF]
Frank J. Twarog, Noel R. Rose
openalex +1 more source
Autoantibodies in systemic autoimmune diseases: specificity and pathogenicity.
In this Review we focus on the initiation of autoantibody production and autoantibody pathogenicity, with a special emphasis on the targeted antigens. Release of intracellular antigens due to excessive cell death or to ineffective clearance of apoptotic ...
J. Suurmond, B. Diamond
semanticscholar +1 more source
Antiphospholipid Syndrome: An Antibody‐Mediated Disease With Emerging Therapeutic Opportunities
Antiphospholipid syndrome (APS) is an autoimmune thromboinflammatory disease characterized by vascular thrombosis, pregnancy morbidity, and other manifestations driven by antiphospholipid autoantibodies. In this review, we present a clinical case that illustrates some diagnostic and therapeutic challenges in managing severe, relapsing APS ...
Thalia G. Newman, Jason S. Knight
wiley +1 more source
Chylomicronemia from GPIHBP1 autoantibodies
Some cases of chylomicronemia are caused by autoantibodies against glycosylphosphatidylinositol-anchored HDL binding protein 1 (GPIHBP1), an endothelial cell protein that shuttles LPL to the capillary lumen.
Kazuya Miyashita+11 more
doaj
AUTOANTIBODIES TO COLON IN GERMFREE RATS MONOCONTAMINATED WITH CLOSTRIDIUM DIFFICILE [PDF]
Sten Hammarström+3 more
openalex +1 more source
Expert Perspective: Diagnosis and Treatment of Castleman Disease
Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen+2 more
wiley +1 more source
Target Proteins in Human Autoimmunity: Cytochromes P450 and Udp-Glycoronosyltransferases
Cytochromes P450 (CYPs) and UDP-glucuronosyltransferases (UGTs) are targets of autoantibodies in several hepatic and extrahepatic autoimmune diseases.
Petra Obermayer-Straub+2 more
doaj +1 more source