Results 191 to 200 of about 251,978 (341)

Prothrombotic Activation of Platelet Pannexin 1 Channels in Antiphospholipid Syndrome

Arthritis &Rheumatology, Accepted Article.
Background ATP is released from platelets through both degranulation and pannexin‐1 (PANX1) channels. ATP then activates P2X receptors to amplify platelet activation via calcium‐dependent signaling. Objective To evaluate the role of platelet PANX1 channels in the pathophysiology of antiphospholipid syndrome (APS), an acquired thrombo‐inflammatory ...
Bruna de Moraes Mazetto Fonseca, Somanathapura K. NaveenKumar, Srilakshmi Yalavarthi, Kavya Sugur, Thalia G. Newman, Claire K. Hoy, Cyrus Sarosh, Jordan K. Schaefer, Ajay Tambralli, Jacqueline A. Madison, Yu Zuo, Fernanda Orsi, Michael Holinstat, Jason S. Knight   +13 more
wiley   +1 more source

Autoantibody landscape and functional role of anti-C-C motif chemokine receptor 8 autoantibodies in systemic sclerosis: post-hoc analysis of a B-cell depletion trial. [PDF]

Nat Commun
Matsuda KM, Chen YY, Ebata S, Iwadoh K, Kotani H, Kuzumi A, Yoshizaki-Ogawa A, Lan CE, Yu HS, Sumida H, Sato S.   +10 more
europepmc   +1 more source

Bardet-Biedl Syndrome, Crohn Disease, Primary Sclerosing Cholangitis, and Autoantibody Positive Thyroiditis: A Case Report and A Review of a Cohort of BBS Patients [PDF]

, 2012
Ugur Halac, Denise Herzog
openalex   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Evidence that Brain-Reactive Autoantibodies Contribute to Chronic Neuronal Internalization of Exogenous Amyloid-β1-42 and Key Cell Surface Proteins During Alzheimer’s Disease Pathogenesis

, 2020
Eric L. Goldwaser, Nimish K. Acharya, Hao Wu, George Godsey, Abhirup Sarkar, Cassandra DeMarshall, Mary C. Kosciuk, Robert G. Nagele   +7 more
openalex   +2 more sources

Diagnostic features of pemphigus vulgaris in patients with pemphigus foliaceus: detection of both autoantibodies, long-term follow-up and treatment responses [PDF]

, 2001
Naveed Sami, Kailash C. Bhol, A. R. Ahmed   +2 more
openalex   +1 more source

Supplementary Figure 3 from Autoantibodies Drive Heart Damage Caused by Concomitant Radiation and PD-1 Blockade

, 2023
Bo Yan, D. Craig Hooper, Zhiyong Yuan, Changli Wang, Yulong Chen, Bo Lu   +5 more
openalex   +1 more source

Interleukin (IL)‐5, Eosinophils and IL‐5 Pathway Inhibitors in Eosinophilic Granulomatosis with Polyangiitis.

Arthritis &Rheumatology, Accepted Article.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

Detection and Validation of Influenza Virus Hemagglutinin Specific, Cross‐Reactive, and Heteroclitic B Cells Induced by a Combination Vaccine Adjuvant

Cytometry Part A, EarlyView.
ABSTRACT Inherent cross‐reactivity for shared epitopes is thought to be critical for vaccines, since this is likely the only way in which a vaccine can be anticipatory, similar to immune responses induced by natural infections. However, measuring antigen‐specific and cross‐reactive B cells remains technically challenging due to low abundance of these ...
Egest J. Pone, Jiin Felgner, Jenny Hernandez‐Davies, Johannes S. Gach, Tyler Albin, D. Huw Davies   +5 more
wiley   +1 more source

Reconsidering the diagnostic potential of thyroperoxidase autoantibodies in chronic spontaneous urticaria. [PDF]

World Allergy Organ J
Aphale P, Shekhar H, Dokania S.
europepmc   +1 more source