Results 61 to 70 of about 251,978 (341)

A Case of Statin-Associated Autoimmune Myopathy. [PDF]

open access: yes, 2017
A 70-year-old previously independent man developed progressive proximal leg weakness resulting in a fall at home suffering traumatic brain injury. He was prescribed a statin medication two years prior, but this was discontinued on admission to the ...
Dokukin, Andrei N   +6 more
core   +3 more sources

Autoantibodies [PDF]

open access: yesJournal of the American Society of Nephrology, 2011
Serologic identification of circulating autoantibodies has proven useful in the diagnosis of patients with autoimmune disorders. In vitro and in vivo [1][1][][2][][3][][4]–[5][5] observations suggest that some autoantibodies are more than just serologic markers; they also participate in ...
Aleeza J, Roth, Ronald J, Falk
openaire   +2 more sources

Cancer Risk in Patients With Systemic Sclerosis: A Nationwide Cohort Study in South Korea 2004 to 2021

open access: yesArthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is a rare autoimmune disease characterized by tissue fibrosis, vasculopathy, and immune dysregulation. Our objectives were to quantify the overall and site‐specific cancer risks in patients with SSc compared to the general population, examine temporal trends in cancer incidence following SSc diagnosis, and explore ...
Jihyun Na   +4 more
wiley   +1 more source

Patients with ACPA-positive and ACPA-negative rheumatoid arthritis show different serological autoantibody repertoires and autoantibody associations with disease activity

open access: yesScientific Reports, 2023
Patients with rheumatoid arthritis (RA) can test either positive or negative for circulating anti-citrullinated protein antibodies (ACPA) and are thereby categorized as ACPA-positive (ACPA+) or ACPA-negative (ACPA−), respectively. In this study, we aimed
Kevin Y. Cunningham   +17 more
doaj   +1 more source

Anti-Saccharomyces cerevisiae antibodies in patients with inflammatory bowel disease and their first-degree relatives: Potential clinical value [PDF]

open access: yes, 2002
Anti-Saccharomyces cerevisiae antibodies (ASCA) have been described as specific markers in Crohn's disease and their healthy first-degree relatives. 171 patients with Crohn's disease, their 105 first-degree relatives, 145 patients with ulcerative colitis
Folwaczny, Christian   +5 more
core   +1 more source

Autoantibodies as Biomarker and Therapeutic Target in Systemic Sclerosis

open access: yesBiomedicines, 2022
Systemic sclerosis (SSc) is a rare connective tissue disorder characterized by immune dysregulation evoking the pathophysiological triad of inflammation, fibrosis and vasculopathy. In SSc, several alterations in the B-cell compartment have been described,
Hanna Graßhoff   +3 more
doaj   +1 more source

γδ T cells affect IL-4 production and B-cell tolerance [PDF]

open access: yes, 2014
γδ T cells can influence specific antibody responses. Here, we report that mice deficient in individual γδ T-cell subsets have altered levels of serum antibodies, including all major subclasses, sometimes regardless of the presence of αβ T cells.
Andrew Getahun   +22 more
core   +1 more source

Trends in Dermatopolymyositis Mortality, 1999–2022: A Nationwide Population‐Based Study, United States

open access: yesArthritis Care &Research, EarlyView.
We report the national burden of dermatopolymyositis mortality over the past quarter century using the US national vital statistics data. Age‐standardized mortality rates for dermatopolymyositis decreased at an annual rate of 3.8% each year, which was higher than the annual percent decrease for deaths from all other causes.
Elizabeth Matz, Ram R. Singh
wiley   +1 more source

Occurence of autoantibodies in healthy Omani individuals

open access: yesSultan Qaboos University Medical Journal, 2001
Objectives: To investigate the occurence of various autoantibodies in the Omani population. Method: Sera from 392 healthy Omani individuals comprising 183 pregnant women and 209 blood donors (183 men and 26 women) were investigated.
Ali A. Al-Jabri, Elizabeth R Richens
doaj  

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