Results 61 to 70 of about 139,183 (310)
Biomedicines, 2023 (1) Background: SARS-CoV-2 infection has been linked to diverse clinical manifestations in humans, including cardiovascular complications. Functional autoantibodies targeting G-protein-coupled receptors have emerged as potential contributors to these ...
Gerd Wallukat +4 more
doaj +1 more source
Immunosuppressive Drugs in Early Systemic Sclerosis and Prevention of Damage Accrual
Arthritis Care &Research, EarlyView.Objective Organ damage in patients with systemic sclerosis (SSc) in individual organs such as the lungs may be prevented by receiving immunosuppressive drugs (ISs). A new measure of global organ damage, the Scleroderma Clinical Trials Consortium Damage Index (SCTC‐DI), has allowed us to investigate whether receiving ISs may reduce global organ damage ...
Murray Baron +29 more
wiley +1 more source
Scientific Reports, 2023 Patients with rheumatoid arthritis (RA) can test either positive or negative for circulating anti-citrullinated protein antibodies (ACPA) and are thereby categorized as ACPA-positive (ACPA+) or ACPA-negative (ACPA−), respectively. In this study, we aimed
Kevin Y. Cunningham +17 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective We aimed to assess differences in baseline characteristics, efficacy, and safety of advanced therapies between male and female patients with axial spondyloarthritis (axSpA) in randomized controlled trials (RCTs). Methods We conducted a systematic literature search for RCTs assessing the efficacy of advanced therapies in patients with axSpA ...
Angel Gao +5 more
wiley +1 more source
European Journal of Immunology, Volume 53, Issue 1, January 2023., 2023 B lineage cells have been identified as therapeutic targets in autoimmune diseases. In the current review article, we provide an overview of novel strategies to target B lineage cells in autoimmune diseases, with a focus on inflammatory rheumatic diseases.
Ana Merino‐Vico +3 more
wiley +1 more source
Estimating AutoAntibody Signatures to Detect Autoimmune Disease Patient Subsets [PDF]
arXiv, 2017 Autoimmune diseases are characterized by highly specific immune responses against molecules in self-tissues. Different autoimmune diseases are characterized by distinct immune responses, making autoantibodies useful for diagnosis and prediction. In many diseases, the targets of autoantibodies are incompletely defined.
arxiv
Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles
Advanced Science, EarlyView.Macrophages play a critical role in several pathophysiological diseases by being involved in the activation of adaptive and innate immune responses. The repolarization of macrophages using gold nanoparticles functionalized with glycans for a more selective targeting toward a restorative phenotype leads to an amelioration of the events.
Jennifer Fernandez Alarcon +25 more
wiley +1 more source
European Journal of Immunology, Volume 52, Issue 12, Page 1972-1979, December 2022., 2022 To investigate atopic immune reactions in response to SARS‐CoV‐2 mRNA vaccinations or mild infections serum IgE and cytokines were analyzed. An atopic environment prone to reactions against aeroallergens was revealed in convalescents but not vaccinated.
Stefan Meltendorf +13 more
wiley +1 more source
Advanced Science, EarlyView.A patented GSK‐3β inhibitor (GSK‐3βi), new benzothiazepinone compounds (BTZs), YC‐4‐3, can modulate the inflammatory status of macrophages in primary immune thrombocytopenia (ITP), and improve the thrombocytopenia in murine ITP models by directly interacting with endoplasmic reticulum (ER) stress response.
Pengcheng Xu +10 more
wiley +1 more source
, 2022 Journal of Cutaneous Immunology and Allergy, Volume 5, Issue 6, Page 227-228, December 2022.
Noritaka Oyama +3 more
wiley +1 more source