Results 111 to 120 of about 137,428 (335)
Genetic analysis of self-associating immunoglobulin G rheumatoid factors from two rheumatoid synovia implicates an antigen-driven response. [PDF]
, 1992 Although much has been learned about the molecular basis of immunoglobulin M (IgM) rheumatoid factors (RFs) in healthy individuals and in patients with mixed cryoglobulinemia and rheumatoid arthritis, little is known about the genetic origins of the ...
Carson, DA +7 more
core
Studies on Autoantibodies in Human Sera [PDF]
, 1953 Alexander S. Wiener +2 more
openalex +1 more source
Editorial: Autoantibodies [PDF]
Frontiers in Immunology, 2019 Holmdahl, Rikard +2 more
openaire +3 more sources
Arthritis &Rheumatology, Accepted Article.Objectives Rheumatoid arthritis (RA) is usually preceded and likely mediated by autoantibodies to citrullinated proteins (ACPAs) that recognize citrulline residues on multiple proteins. Conversion of arginine into citrulline is performed by enzymes called peptidyl arginine deiminases (PADs).
Philippe P. Pagni +10 more
wiley +1 more source
CAQ Corner: Immune‐mediated complications
, 2022 Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley +1 more source
Anti-idiotypic Antibodies against BP-IgG Prevent Type XVII Collagen Depletion
Frontiers in Immunology, 2017 Bullous pemphigoid (BP) mainly targets type XVII collagen (COL17). Intravenous immunoglobulin (IVIg) is used to treat numerous autoimmune diseases, including BP. The major mechanism of action for IVIG is thought to be its immunomodulatory effect. However,
Mayumi Kamaguchi +7 more
doaj +1 more source
B cell reductive therapy with rituximab in the treatment of rheumatoid arthritis. [PDF]
, 2009 The approach to treating autoimmune disorders is currently undergoing a significant change in focus. As therapies are developed that are more precise in targeting the pathogenesis for these diseases, patients experience significantly fewer side effects ...
Sands, Jacob, Tuscano, Joseph M
core +2 more sources
Arthritis &Rheumatology, Accepted Article.Objectives The effect of the shared epitope (SE), and valine at position 11 (Val11) of HLA‐DRB1, on the activation of CD4+ T cells, is expected to be diminished by abatacept, a co‐stimulation blocker. However, published evidence on the value of genetic stratification for abatacept treatment is conflicting.
Chuan Fu Yap +14 more
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background Angiotensin II type 1 receptor (AT1R) autoantibody (AT1‐AA) was first identified as a causative factor in preeclampsia. Unlike physiological ligand angiotensin II (Ang II), AT1‐AA can induce vasoconstriction in a sustained manner, causing a ...
Jingwei Bian +9 more
doaj +1 more source