Results 131 to 140 of about 235,603 (337)

Clinical and serological features of systemic sclerosis in a multicenter African American cohort: Analysis of the genome research in African American scleroderma patients clinical database. [PDF]

open access: yes, 2017
Racial differences exist in the severity of systemic sclerosis (SSc). To enhance our knowledge about SSc in African Americans, we established a comprehensive clinical database from the largest multicenter cohort of African American SSc patients assembled
Boin, Francesco   +28 more
core   +1 more source

Targeted Degradation of sGRP78 Alleviates the Immunosuppressive Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
Soluble GRP78 (sGRP78) is identified as a novel tumor‐derived soluble factor that induces regulatory T cells (Treg). sGRP78 serves as an excellent serological biomarker for predicting the efficacy of neoadjuvant therapy in breast cancer patients. sGRP78 specifically binds to B cells, inducing the expression of IL‐10 and PD‐L1, thereby promoting Treg ...
Zhenghao Wu   +10 more
wiley   +1 more source

Studies on Autoantibodies in Human Sera [PDF]

open access: bronze, 1953
Alexander S. Wiener   +2 more
openalex   +1 more source

Identifying Key Questions and Challenges in Microchimerism Biology

open access: yesAdvanced Science, EarlyView.
This study identifies key unanswered questions about microchimerism, the presence of cells from one individual living in another. Experts highlight how these cells may affect health, pregnancy, and disease. This study outlines research priorities and challenges in detecting and studying these rare microchimeric cells, aiming to guide future discoveries
Kristine J. Chua   +31 more
wiley   +1 more source

Flightless I Alters the Inflammatory Response and Autoantibody Profile in an OVA-Induced Atopic Dermatitis Skin-Like Disease

open access: yesFrontiers in Immunology, 2018
Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease characterized by excessive inflammation and disrupted skin barrier function. Although the etiology of AD is not completely understood, clinical and basic studies suggest increasing ...
Zlatko Kopecki   +4 more
doaj   +1 more source

Lack of extensive mutations in the VH5 genes used in common B cell chronic lymphocytic leukemia. [PDF]

open access: yes, 1993
B cell chronic lymphocytic leukemia (CLL) is a malignancy of the CD5+ B cells. Prior studies indicated that CLL B cells generally express immunoglobulin (Ig) VH and VL genes with little or no somatic mutations.
Kipps, TJ, Rassenti, LZ
core  

Autoantibody Epitope Spreading in the Pre-Clinical Phase Predicts Progression to Rheumatoid Arthritis

open access: yesPLoS ONE, 2012
Rheumatoid arthritis (RA) is a prototypical autoimmune arthritis affecting nearly 1% of the world population and is a significant cause of worldwide disability.
J. Sokolove   +14 more
semanticscholar   +1 more source

Autoimmune Hepatobiliary Disease and Cryoglobulins in Peripheral Blood

open access: yesAmerican Journal of Hematology, EarlyView.
Cryoglobulins in Autoimmune Hepatobiliary Disease.
Anna Shestakova   +2 more
wiley   +1 more source

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