Results 131 to 140 of about 5,372 (258)
Improvement of BsAPA Aspartic Protease Thermostability via Autocatalysis-Resistant Mutation
An aspartic protease gene (Bsapa) was cloned from Bispora sp. MEY-1 and expressed in Pichia pastoris. The recombinant BsAPA showed maximal activity at pH 3.0 and 75 °C and remained stable at 70 °C and below, indicating the thermostable nature of BsAPA ...
Xiaoyun Su (139853) +9 more
core +1 more source
Artificial particulate matter with high iron content and varied iron speciation accelerates cellulose acetate degradation, increasing chemical instability during aging. These findings identify a previously underexplored deterioration pathway and demonstrate that airborne pollutant composition can critically influence the preservation of historical ...
Francesca Azolini +3 more
wiley +1 more source
Assessment of Stoichiometric Autocatalysis across Element Groups
Autocatalysis has been proposed to play critical roles during abiogenesis. These proposals are at odds with a limited number of known examples of abiotic (and, in particular, inorganic) autocatalytic systems that might reasonably function in a prebiotic ...
Zhen Peng (539724) +3 more
core +2 more sources
Chronic intermittent hypoxia induced downregulation of PINK1, leading to deficient mitophagy, accumulation of damaged mitochondria and excessive ROS production, which further promoted the NLRP3 inflammasome complex assembly to trigger pyroptosis and the IL‐1β/IL‐18 release in renal tubular epithelial cells.
Yuwei Zhang, Hongyan Tai
wiley +1 more source
Sulfide capture of Co and Ni after peroxymonosulfate-assisted autocatalysis of EDTA complexes
EDTA-enhanced Co and Ni extraction from low-grade ultramafic ore deposits can be promising if coupled to a concentration process for those elements. This study evaluates the efficiency of autocatalysis and decomplexation of metal-EDTA chelates using ...
Jennifer L. Houghton +3 more
doaj +1 more source
3D Cellular Automata of Polymer Structural Response to Solvent Quality
A minimal three‐dimensional cellular automaton captures solvent‐dependent polymer collapse, θ‐like scaling, swelling, and aggregation through simple local interaction rules. Radius‐of‐gyration scaling identifies the θ regime, while multichain simulations reveal that free chain ends and periodic self‐connection strongly govern structural reorganization,
Vasilii Korotenko +2 more
wiley +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Abstract Non‐standard amino acids (ncAAs) together with synthetic additions (like caps and linkers) are of wide interest for protein design and pharmaceutical optimization, as they can improve physicochemical properties and possibly reshape protein structure. Their inclusion in experimental structures has not been explored systematically.
Alex Waldherr +2 more
wiley +1 more source
Stability conditions of chemical networks in a linear framework
Autocatalytic chemical reaction networks can collectively replicate or maintain their constituents despite degradation reactions only above a certain threshold, which we refer to as the decay threshold.
Armand Despons +2 more
doaj +1 more source
An ideal electrolyte additive, particularly for Si‐based anodes, should (i) promote the formation of an effective SEI, i.e., passivating and suppressing LiPF6/SiOx‐contact, (ii) minimize active Li loss (ALL) through efficient SEI formation, (iii) ideally enable “SEI‐waste” recovery and/or (iv) undergo sacrificial oxidation for prelithiation purposes ...
Anindityo Arifiadi +13 more
wiley +1 more source

