Results 111 to 120 of about 3,278 (226)

TopCas: Topology‐Gated Cas12a via DNA‐RNA Chimeric Circular crRNA for Amplification‐Free Nucleic Acid Detection and Conditional Gene Editing

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
The TopCas platform utilizes an engineered DNA‐RNA chimeric circular crRNA to establish topology‐gated control over CRISPR‐Cas12a activity, enabling target‐triggered self‐catalytic amplification (preamplification‐free). This system seamlessly integrates highly sensitive molecular diagnostics with conditionally controlled gene editing, demonstrating ...
Shun Zhang   +7 more
wiley   +1 more source

Enumeration of Autocatalytic Subsystems in Large Chemical Reaction Networks. [PDF]

open access: yesJ Chem Theory Comput
Golnik R   +3 more
europepmc   +1 more source

Practical Lithium–Sulfur Batteries: An Integrated Design Roadmap from High‐Loading Cathodes to High‐Energy Pouch Cells

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
This review presents an integrated design roadmap for practical lithium–sulfur batteries, moving beyond isolated material breakthroughs to the synergistic combination of three interdependent frontiers: Scale‐Up, Electrolyte‐Cathode Synergy, and AI/ML Data‐Driven Design.
Shihzad Shakil   +6 more
wiley   +1 more source

Light‐Controlled Peptide Self‐Assembly: From Physicochemical Principles to Emerging Biomedical Applications

open access: yesAggregate, Volume 7, Issue 6, June 2026.
This review surveys recent advances in light‐controlled peptide self‐assembly for the design of smart soft matter. It summarizes the underlying physicochemical principles, including thermodynamic control for reshaping free‐energy landscapes, and nonequilibrium control to produce kinetically trapped states and dissipative structures.
Lidong Chen   +7 more
wiley   +1 more source

Geometric Stabilization of Biomolecular Chirality in Open Systems

open access: yesChirality, Volume 38, Issue 6, June 2026.
Entropic topology favors orientation‐preserving deformations in molecular configuration space, leading to a spontaneous statistical bias toward right‐handed α$$ \alpha $$‐helices. The figure illustrates how configurations with positive determinant (dextral) occupy a larger accessible volume of microstates, providing a purely geometric‐entropic ...
Vicente Domínguez‐Arca
wiley   +1 more source

A Pseudo‐Two‐Dimensional Reaction–Diffusion Model for Rational Design of Antibacterial–Antioxidant Ag–ZnO/Fucoidan Nanocomposites

open access: yesEngineering Reports, Volume 8, Issue 6, June 2026.
A pseudo‐two‐dimensional (P2D) reaction–diffusion framework is proposed to model reactive oxygen species (ROS) generation, transport, and scavenging in Ag–ZnO/Fucoidan nanocomposites. Spatially segregated ROS source (Ag–ZnO) and sink (fucoidan) domains are embedded into a one‐dimensional computational model, capturing nonlinear feedback between site ...
Mohamed Abu Shuheil   +8 more
wiley   +1 more source

Processing–Structure–Degradation Relationships in Additively Manufactured and Cast PLA/PCL Blends

open access: yesMacromolecular Materials and Engineering, Volume 311, Issue 6, June 2026.
Electrohydrodynamic printing (E‐writing mode) and solution casting are used to fabricate PLA/PCL systems with different structures, enabling a direct comparison of processing‐ structure‐degradation relationships. The results show that morphology plays a key role in controlling rheological behavior, mechanical properties, and biodegradation, providing a
Fatemeh Sadat Mahdavi   +24 more
wiley   +1 more source

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